International Journal of Radiation Oncology * Biology * Physics
Volume 70, Issue 4 , Pages 1195-1201, 15 March 2008

Patterns of Practice of Palliative Radiotherapy in Africa, Part 1: Bone and Brain Metastases

  • Vinay Sharma, M.D., Ph.D.

      Affiliations

    • Johannesburg Hospital, University of Witwatersrand, Johannesburg, South Africa
    • Corresponding Author InformationReprint requests to: Vinay Sharma, M.D., Department of Radiation Oncology, Johannesburg Hospital, University of Witwatersrand, Parktown, Johannesburg, South Africa. Tel: (+27) 11-481-2124; Fax: (+27) 11-642-9185
  • ,
  • Papa Macoumba Gaye, M.Med.

      Affiliations

    • Institut Curie, Hopital Aristide le Dentec, Univesite Cheikh Anta Diop de Dakar, Dakar, Senegal
  • ,
  • Sherif Abdel Wahab, M.D.

      Affiliations

    • Ain Shams University, Abbasia, Cairo, Egypt
  • ,
  • Ntokozo Ndlovu, M.Med.

      Affiliations

    • Medical School, Radiotherapy Centre, Harare, Zimbabwe
  • ,
  • Twalib Ngoma, F.F.R.

      Affiliations

    • Ocean Road Hospital, Ocean Road Cancer Institute, Dar Es Salaam, Tanzania
  • ,
  • Verna Vanderpuye, F.W.A.C.S.

      Affiliations

    • Korle Bu Teaching Hospital, Accra, Ghana
  • ,
  • Anthonia Sowunmi, M.D.

      Affiliations

    • Teaching Hospital, University of Lagos, Surulere, Lagos, Nigeria
  • ,
  • Joseph Kigula-Mugambe, M.Med.(Rad.), M.S.C.(R.Onc.)

      Affiliations

    • Radiotherapy Department, Makerere University, Kampala, Uganda
  • ,
  • Branislav Jeremic, M.D., Ph.D.

      Affiliations

    • International Atomic Energy Agency, Vienna, Austria

Received 5 June 2007; received in revised form 24 July 2007; accepted 27 July 2007. published online 29 October 2007.

Purpose

To provide data on the pattern of practice of palliative radiotherapy (RT) on the African continent.

Methods and Materials

A questionnaire was distributed to participants in a regional training course of the International Atomic Energy Agency in palliative cancer care and sent by e-mail to other institutions in Africa. Requested information included both infrastructure and human resources available and the pattern of RT practice for metastatic and locally advanced cancers.

Results

Of 35 centers contacted, 24 (68%) completed the questionnaire. Although RT is used by most centers for most metastatic cancers, liver and lung metastases are treated with chemotherapy. Of 23 centers, 14 (61%) had a single RT regimen as an institutional policy for treating painful bone metastases, but only 5 centers (23%) of 23 used 8 Gy in 1 fraction. Brain metastases were being treated by RT to the whole brain to 30 Gy in 10 fractions, either exclusively (n = 13, 56%) or in addition to the use of 20 Gy in 5 fractions (n = 3, 14%).

Conclusion

Radiotherapy is a major component of treatment of cancer patients in African countries. There is consensus among few centers for treatment schedules for almost all sites regarding time and dose-fractionation characteristics of RT regimens used and/or indications for the use of RT in this setting.

Radiotherapy, Palliation, Metastatic disease, Patterns of care

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 Presented at Regional (AFRA) Training Course on Palliative Care Dar Es Salaam, Tanzania, September 5–9, 2005.

 Conflict of interest: none.

PII: S0360-3016(07)03915-6

doi:10.1016/j.ijrobp.2007.07.2381

International Journal of Radiation Oncology * Biology * Physics
Volume 70, Issue 4 , Pages 1195-1201, 15 March 2008