International Journal of Radiation Oncology * Biology * Physics
Volume 47, Issue 5 , Pages 1229-1234 , 15 July 2000

Progesterone receptor is a favorable prognostic factor of radiation therapy for adenocarcinoma of the uterine cervix

  • Yoshiyuki Suzuki, M.D.

      Affiliations

    • Division of Radiation Medicine, National Institute of Radiological Sciences, Chiba, Japan
    • Department of Radiology and Radiation Oncology, Gunma University School of Medicine, Maetashi, Japan
    • ,
  • Takashi Nakano, M.D.

      Affiliations

    • Division of Radiation Medicine, National Institute of Radiological Sciences, Chiba, Japan
    • Corresponding Author InformationReprint requests to: Dr. Takashi Nakano, Division of Radiation Medicine, National Institute of Radiological Sciences, 4-9-1, Anagawa, Inage-ku, Chiba-shi, Chiba 263-0024, Japan.
    • ,
  • Tatsuo Arai, M.D.

      Affiliations

    • Division of Radiation Medicine, National Institute of Radiological Sciences, Chiba, Japan
    • ,
  • Shinroku Morita, M.D.

      Affiliations

    • Division of Radiation Medicine, National Institute of Radiological Sciences, Chiba, Japan
    • ,
  • Hirohiko Tsujii, M.D.

      Affiliations

    • Division of Radiation Medicine, National Institute of Radiological Sciences, Chiba, Japan
    • ,
  • Kuniyuki Oka, M.D.

      Affiliations

    • Department of Pathology, Mito Saiseikai General Hospital, Mito, Japan

,Accepted 2 February 2000.

References 

  1. Brand E, Berek JS, Hacker NF. Controversies in the management of cervical adenocarcinoma. Obstet Gynecol. 1988;71:261–269
  2. Kleine W, Rau K, Schwoeorer D, et al.  Prognosis of the adenocarcinoma of the cervix uteri (A comparative study). Gynecol Oncol. 1989;35:145–149
  3. Eifel PJ, Morris M, Oswald MJ, et al.  Adenocarcinoma of the uterine cervix (Prognosis and patterns of failure in 367 cases). Cancer. 1990;65:2507–2514
  4. Silcocks PBS, Thornton-Jones H, Murphy M. Squamous and adenocarcinoma of the uterine cervix (A comparison using routine data). Br J Cancer. 1987;55:321–325
  5. Leminen A, Paavonen J, Forss M, et al.  Adenocarcinoma of the uterine cervix. Cancer. 1990;65:53–59
  6. Chen RJ, Chang DY, Yen ML, et al.  Prognostic factors of primary adenocarcinoma of the uterine cervix. Gynecol Oncol. 1998;69:157–164
  7. Sanborn BN, Held B, Kuo HS. Specific estrogen binding proteins in human cervix. J Steroid Biochem. 1975;6:1107–1112
  8. Sanborn BN, Held B, Kuo HS. Hormone action in human cervix (II. Specific progesterone binding proteins in human cervix). J Steroid Biochem. 1976;7:665–672
  9. Masood S, Rhatigan RM, Wilkinson EW, et al.  Expression and prognostic significance of estrogen and progesterone receptors in adenocarcinoma of the uterine cervix (An immunocytochemical study). Cancer. 1993;72:511–518
  10. Fujiwara H, Tortolero-Luna G, Mitchell MF, et al.  Adenocarcinoma of the cervix. Cancer. 1997;79:505–512
  11. Clark GM, McGuire WL, Hubay CA, et al.  Progesterone receptors as a prognostic factor in stage II breast cancer. N Engl J Med. 1983;309:1343–1347
  12. Fukuda K, Mori M, Uchiyama M, et al.  Prognostic significance of progesterone receptor immunohistochemistry in endometrial carcinoma. Gynecol Oncol. 1998;69:220–225
  13. Kommoss F, Pfisterer J, Thome M, et al.  Steroid receptors in ovarian carcinoma (Immunohistochemical determination may lead to new aspects). Gynecol Oncol. 1992;47:317–322
  14. Bizzi A, Codegoni AM, Landoni F, et al.  Steroid receptors in epthelial ovarian carcinoma (Relation to clinical parameters and survival). Cancer Res. 1988;48:6222–6226
  15. Chambers JJ, Maclusky N, Eisenfield A, et al.  Estrogen and progestin receptor levels as prognostic factors for survival in endometrial cancer. Gynecol Oncol. 1988;31:65–77
  16. McGuire WL. Estrogen receptors in human breast cancer. J Clin Invest. 1973;52:73–77
  17. Arai T, Nakano T, Morita S, et al.  High dose rate remote after-loading intracavitary radiation therapy for cancer of the uterine cervix. Cancer. 1992;69:175–180
  18. Nakano T, Arai T, Morita S, et al.  Radiation therapy alone for adenocarcinoma of the uterine cervix. Int J Radiat Oncol Biol Phys. 1995;32:1331–1336
  19. Arai T, Morita S, Kutsutani Y, et al.  Special report no. 17. Br J Radiol. 1978;18:89–92
  20. Ghandour FA, Attanoos R, Nahar K, et al.  Immunocytochemical localization of oestrogen and progesterone receptors in primary adenocarcinoma of the cervix. Histopathology. 1994;24:49–55
  21. Lykkesfeldt AE, Madsen MW, Briand P. Altered expression of estrogen-regulated genes in a tamoxifen-resistant and ICI 164,384 and ICI 182,780 sensitive human breast cancer cell line, MCF-7/TAMR-11. Cancer Res. 1994;54:1587–1595
  22. Paulsen GHU, Strickert T, Marthinsen ABL, et al.  Changes in radiation sensitivity and steroid receptor content induced by hormonal agents and ionizing radiation in breast cancer cells in vitro. Acta Oncol. 1996;35:1011–1019
  23. Scambia G, Panici PB, Baiocchi G, et al.  Steroid hormone receptors in carcinoma of the cervix (Lack of response to an antiestrogen). Gynecol Oncol. 1990;37:323–326
  24. Greman R, Virolaine E, Shapira A, et al.  In vivo effects of tamoxifen on UM-SCC head and neck cancer cell lines (Correlation with the estrogen and progesterone receptor content). Int J Cancer. 1987;39:77–81

PII: S0360-3016(00)00495-8

doi: 10.1016/S0360-3016(00)00495-8

International Journal of Radiation Oncology * Biology * Physics
Volume 47, Issue 5 , Pages 1229-1234 , 15 July 2000

Article Tools

* Image Usage & Resolution