International Journal of Radiation Oncology * Biology * Physics
Volume 48, Issue 4 , Pages 933-941 , 1 November 2000

Relationship of family history and outcome after breast conservation therapy in women with ductal carcinoma in situ of the breast

Presented in part at the 41st Annual Meeting of the American Society for Therapeutic Radiology and Oncology, San Antonio, TX, October 31–November 4, 1999.

  • Eleanor E.R Harris, M.D.

      Affiliations

    • University of Pennsylvania, Department of Radiation Oncology, Philadelphia, PA, USA
    • Corresponding Author InformationReprint requests to: Eleanor E. R. Harris, M.D., Department of Radiation Oncology, Hospital of the University of Pennsylvania, 3400 Spruce Street, 2 Donner Building, Philadelphia, PA 19104. Tel: (215) 662-2337; Fax: (215) 349-5445
    • ,
  • Delray J Schultz, Ph.D.

      Affiliations

    • Millersville University, Department of Mathematics, Millersville, PA, USA
    • ,
  • Christopher A Peters

      Affiliations

    • University of Pennsylvania, Department of Radiation Oncology, Philadelphia, PA, USA
    • ,
  • Lawrence J Solin, M.D.

      Affiliations

    • Millersville University, Department of Mathematics, Millersville, PA, USA

,Accepted 1 June 2000.

References 

  1. Pharoah PDP, Day NE, Duffy S, et al.  Family history and the risk of breast cancer (A systematic review and meta-analysis). Int J Cancer. 1997;71:800–809
  2. Lynch HT, Watson P, Conway T, et al.  Breast cancer family history as a risk factor for early onset breast cancer. Breast Cancer Res Treat. 1988;11:263–267
  3. Chaudary MA, Millis RR, Bulbrook RD, et al.  Family history and bilateral breast cancer. Breast Cancer Res Treat. 1985;5:201–205
  4. Brody L, Biesecker BB. Breast cancer susceptibility genes (BrCa1 and BrCa2). Medicine. 1998;77:208–226
  5. Meyn M. Ataxia-telangiectasia, cancer and the pathobiology of the ATM gene. Clin Genet. 1999;55:289–304
  6. Kleihues P, Schauble B, zur Hausen A, et al.  Tumors associated with p53 germline mutations (A synopsis of 91 families). Am J Pathol. 1997;150:1–13
  7. Mohney BG, Robertson DM, Schomberg PJ, et al.  Second nonocular tumors in survivors of heritable retinoblastoma and prior radiation therapy. Am J Opthalmol. 1998;126:269–277
  8. Buchholz TA, Weil MM, Story MD, et al.  Tumor suppressor genes and breast cancer. Radiat Oncol Invest. 1998;7:55–65
  9. Claus EB, Risch N, Thompson WD, et al.  Relationship between histopathology and family history of breast cancer. Cancer. 1993;71:47–53
  10. Amican Joint Committee on Cancer. AJCC Cancer Staging Manual. 5th ed. Philadelphia: Lippincott-Raven Publishers; 1997. p. 171–180.
  11. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. Am Stat Assoc J. 1958;53:457–481
  12. Mantel N. Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep. 1966;50:163–170
  13. Agresti A. Categorical Data Analysis. New York: John Wiley and Sons Publishers; 1990;
  14. Fisher B, Constantino J, Redmond C, et al.  Lumpectomy compared with lumpectomy and radiation for the treatment of intraductal breast cancer. N Engl J Med. 1993;328:1581–1586
  15. Julien JP, Bijker N, Fentiman IS, et al.  Radiotherapy in breast-conserving treatment for ductal carcinoma in situ (DCIS) (First results of the EORTC randomised phase III trial10853). Lancet. 2000;355:528–533
  16. Solin LJ, McCormick B, Recht A, et al.  Mammographically detected, clinically occult ductal carcinoma in situ treated with breast-conserving surgery and definitive breast irradiation. Cancer J Sci Am. 1996;2:158–165
  17. Rosen PP, Lesser ML, Senie RT, et al.  Epidemiology of breast cancer III (Relationship of family history to tumor type). Cancer. 1982;50:171–179
  18. Israeli D, Tartter PI, Brower ST. The significance of family history for patients with carcinoma of the breast. J Am Coll Surg. 1994;179:29–32
  19. Sun CC, Lenoir G, Lynch H, et al.  In-situ breast cancer and BRCA1. Lancet. 1996;348:408
  20. Robson M, Rajan P, Rosen PP, et al.  BrCa-associated breast cancer. Absence of a characteristic immunophenotpye. Cancer Res. 1998;58:1839–1842
  21. Jacquemier J, Eisinger F, Guinebretiere J-M, et al.  Intraductal component and BrCa1-associated breast cancer. Lancet. 1996;348:1098
  22. Ernster VL, Barclay J. Incidence of and treatment for ductal carcinoma in situ (DCIS) of the breast. JAMA. 1996;275:913–918
  23. Hiramatsu H, Bornstein BA, Recht A, et al.  Local recurrence after conservative surgery and radiation therapy for ductal carcinoma in situ (Possible importance of family history). Cancer J Sci Am. 1995;1:55–61
  24. McCormick B, Rosen PP, Kinne D, et al.  Duct carcinoma in situ of the breast (An analysis of local control after conservation surgery and radiotherapy). Int J Radiat Oncol Biol Phys. 1991;21:289–292
  25. Fowble BL, Hanlon AL, Fein DA, et al.  Results of conservative surgery and radiation for mammographically detected ductal carcinoma in situ (DCIS). Int J Radiat Oncol Biol Phys. 1997;38:949–957
  26. Sananes S, Clough KB, Zafrani B, et al.  Intraductal cancer of the breast in women under age 35 years. Bulletin du Cancer. 1996;83:395–399
  27. Kestin LL, Goldstein NS, Lacerna MD, et al.  Factors associated with local recurrence of mammographically detected ductal carcinoma in situ in patients given breast-conserving therapy. Cancer. 2000;88:596–607
  28. Chen Y, Thompson W, Semenciw R, et al.  Epidemiology of contralateral breast cancer. Cancer Epidemiol Biomarkers Prev. 1999;8:855–861
  29. Gogas J, Markopoulos C, Skandalakis P, et al.  Bilateral breast cancer. Am J Surg. 1993;59:733–735
  30. Horn PL, Thompson WD. Risk of contralateral breast cancer (Associations with factors related to initial breast cancer). Am J Epidemiol. 1988;128:309–323
  31. Slattery ML, Kerber RA. A comprehensive evaluation of family history and breast cancer (The Utah Population Database). JAMA. 1993;270:1563–1568
  32. Chabner E, Nixon A, Gelman R, et al.  Family history and treatment outcome in young women after breast-conserving surgery and radiation therapy for early stage breast cancer. J Clin Oncol. 1998;16:2045–2051
  33. Kunkler IH, Jack WL, Kerr GR. The influence of a family history of breast cancer on the risk of developing a contralateral primary (A long-term follow-up study). Int J Radiat Oncol Biol Phys. 1999;45:231
  34. Pierce LJ, Strawderman M, Narod SA, et al.  No deleterious effects of radiotherapy in women who are heterozygotes for a BRCA-1 or BRCA-2 mutation following breast-conserving therapy. Proc ASCO. 1999;18:86a
  35. Mills JM, Schultz DJ, Solin LJ. Preservation of cosmesis with low complication risk after conservative surgery and radiotherapy for ductal carcinoma in situ of the breast. Int J Radiat Oncol Biol Phys. 1997;39:637–641
  36. Hetelekidis S, Collins L, Silver B, et al.  Predictors of local recurrence following excision alone for ductal carcinoma in situ. Cancer. 1998;85:427–431

PII: S0360-3016(00)00726-4

International Journal of Radiation Oncology * Biology * Physics
Volume 48, Issue 4 , Pages 933-941 , 1 November 2000

Article Tools

* Image Usage & Resolution