« Previous
Next »
International Journal of Radiation Oncology * Biology * Physics
Volume 49, Issue 2
, Pages 345-351
, 1 February 2001
The translational research chain: is it delivering the goods?
References
- Continuous hyperfractionated accelerated radiotherapy (CHART) versus conventional radiotherapy in non-small-cell lung cancer (A randomised multicentre trial). Lancet. 1997;350:161–165
- . Hypoxia specific cytotoxins in cancer therapy. Semin Radiat Oncol. 1996;6:22–36
- . Modification of hypoxia-induced radioresistence in tumors by the use of oxygen and sensitizers. Semin Radiat Oncol. 1996;6:10–21
- . Combined chemotherapy and radiation therapy in surgically unresectable regionally advanced non-small cell lung cancer. Semin Radiat Oncol. 1996;6:86–91
- . Radiotherapy and concurrent chemotherapy for the treatment of locally advanced head and neck squamous cell carcinoma. Semin Radiat Oncol. 1998;8:237–246
- . Concurrent chemotherapy and radiation for locally advanced cervical cancer (The new standard of care). Semin Radiat Oncol. 2000;10:44–50
- Endostatin (An endogenous inhibitor of angiogenesis and tumor growth). Cell. 1997;88:277–285
- In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody. Clin Cancer Res. 2000;6:701–708
- Radiation-induced renal damage (The effects of hyperfractionation). Radiat Res. 1984;98:407–420
- The kinetics of repair in mouse lung after fractionated irradiation. Int J Radiat Biol Relat Stud Phys Chem Med. 1987;52:903–919
- . A review of α/β ratios for experimental tumours (Implications for clinical studies on altered fractionation). Int J Radiat Oncol Biol Phys. 1985;11:87–96
- Linear–quadratic analysis of tumour response to fractionated radiotherapy (A study on human squamous cell carcinoma xenografts). Int J Radiat Biol. 1997;73:197–205
- . Three A’s of normal tissue repopulation. A review of mechanisms. Int J Radiat Biol. 1997;72:635–644
- Impact of overall treatment time on local control of slow growing human GL squamous cell carcinoma in nude mice treated by fractionated irradiation. Radiother Oncol. 1999;50:107–111
-
.
The volume effect in radiotherapy—Its biological significance.
Br J Radiol. 1997;70:S32–S40
- . Re-treatment after full-course radiotherapy (Is it a viable option?). Acta Oncol. 1999;38:855–862
- Stromal fibroblasts are required for PC-3 human prostate cancer cells to produce capillary-like formation of endothelial cells in a three-dimensional co-culture system. Anticancer Res. 1997;17:1551–1557
- Inhibiting Ras prenylation increases the radiosensitivity of human tumor cell lines with activating mutations of ras oncogenes. Cancer Res. 1998;58:1754–1761
- . Animal systems for translational research in radiation oncology. Acta Oncol. 1999;38:829–838
- . Experimental radiotherapy (A brief history). Radiat Res. 1998;150:S157–S169
-
Kallman RF. Some aspects of the time-dose-relationship in spontaneous and transplanted mouse tumors irradiated in vivo. In: Research in radiotherapy, approaches to chemical sensitization. Report No. 35. Washington, DC: National Academy of Sciences, 1961.
- . Response of spontaneous mammary carcinoma of the C3H mouse to x-irradiation given under conditions of local tissue anoxia. J Natl Cancer Inst. 1963;31:497–509
-
Gillette EL. Hyperthermia effects in animals with spontaneous tumors. National Cancer Institute monograph 61: 3rd International Symposium Cancer Therapy Hyperthermia, Drugs and Radiation. NIH publication no. 82-2437. Washington, DC: US Government Printing Office; 1982. p. 361–364.
- The tolerance of primate cord to re-irradiation. Int J Radiat Oncol Biol Phys. 1993;25:459–464
-
.
Mutation and childhood cancer (A probabilistic model for the incidence of retinoblastoma).
Proc Natl Acad Sci USA. 1975;72:5116–5120
- . Mutations of bacteria from virus sensitivity to virus resistance. Genetics. 1943;28:491–511
- . Survival models for familial aggregation of cancer. Environ Health Perspect. 1990;87:27–35
- . A generalized F-mixture model for cure rate estimation. Stat Med. 1998;17:813–830
-
.
Clinical trials. London: Academic Press; 1980;
- What difference does it make to be treated in a clinical trial? A pilot study. Clin Invest Med. 1996;19:179–183
- . Towards evidence based radiation oncology (Improving the design, analysis, and reporting of clinical outcome studies in radiotherapy). Radiother Oncol. 1998;46:5–18
- . Dose, time and fractionation (A clinical hypothesis). Clin Radiol. 1969;20:1–7
- Experiments with fractionated X-ray treatment of the skin of pigs. I. Fractionation up to 28 days. Br J Radiol. 1963;36:188–196
-
.
Time–dose relationships in radiotherapy.
In:
Steel GG editors. Basic clinical radiobiology. London: Arnold; 1997;p. 98–105
- . The relationship of acute and late skin injury in 2 and 5 fraction/week (γ-ray therapy). Int J Radiat Oncol Biol Phys. 1978;4:595–601
- Changes in early and late radiation responses with altered dose fractionation (Implications for dose–survival relationships). Int J Radiat Oncol Biol Phys. 1982;8:219–226
- Hyperfractionation. Int J Radiat Oncol Biol Phys. 1982;8:1807–1809
- Hyperfractionation versus conventional fractionation in oropharyngeal carcinoma (Final analysis of a randomized trial of the EORTC cooperative group of radiotherapy). Radiother Oncol. 1992;25:231–241
-
.
Effect-independent measures of tissue responses to fractionated irradiation.
Int J Radiat Oncol Biol Phys. 1984;45:1–10
- . Tissue repair capacity and repair kinetics deduced from multifractionated or continuous irradiation regimens with incomplete repair. Br J Cancer. 1984;49(Suppl. VI):263–269
- Impact of spinal cord repair kinetics on the practice of altered fractionation schedules. Radiother Oncol. 1992;25:287–294
- . Repair halftimes estimated from observations of treatment-related morbidity after CHART or conventional radiotherapy in head and neck cancer. Radiother Oncol. 1999;53:219–226
-
Joiner MC, Marples B, Lambin P; et al. Low-dose hypersensitivity: current status and possible mechanisms. Proceedings of ICTR 2000, Lugano, Switzerland. Int J Radiat Oncol Biology Phys 2000 In press.
-
.
Changes of cell proliferation characteristics in a rat rhabdomyosarcoma before and after x-irradiation.
Eur J Cancer. 1969;5:173–189
- . Dependence of response of a C3H mammary carcinoma to fractionated irradiation on fraction number and intertreatment interval. Radiat Res. 1977;72:440–454
- . The hazard of accelerated tumor clonogen repopulation during radiotherapy. Acta Oncol. 1988;27:131–146
- Conventional radiotherapy as the primary treatment of squamous cell carcinoma (SCC) of the head and neck. A randomized multicenter study of 5 versus 6 fractions per week—Preliminary report from the DAHANCA 6 and 7 trial (Abstr.). Radiother Oncol. 1996;40:S31
- Accelerated fractionation (AF) compared to conventional fractionation (CF) improves loco-regional control in the radiotherapy of advanced head and neck cancers (Results of the EORTC 22851 randomized trial). Radiother Oncol. 1997;44:111–121
- A randomised multicentre trial of CHART versus conventional radiotherapy in head and neck cancer. Radiother Oncol. 1997;44:123–136
- A Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas (First report of RTOG 9003). Int J Radiat Oncol Biol Phys. 2000;48:7–16
- A randomised phase III study of accelerated or standard fraction radiotherapy with or without concurrent carboplatin in inoperable non-small cell lung cancer (Final report of an Australian multi-centre trial). Radiother Oncol. 1999;52:129–136
- . Accelerated radiation therapy in non-small cell lung cancer. Radiother Oncol. 1999;52:97–99
- The value of pretreatment cell kinetic parameters as predictors for radiotherapy outcome in head and neck cancer (A multicenter analysis). Radiother Oncol. 1999;50:13–23
-
Board of Faculty of Clinical Oncology, The Royal College of Radiologists. Guidelines for the management of the unscheduled interruption or prolongation of a radical course of radiotherapy. Roy Coll Radiologists Lond 1996.
- . Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinoma of the head and neck. Cancer Res. 1999;59:1935–1949
☆ This work has been supported in part by the Deutsche Forschungsgemeinschaft, the Cancer Research Campaign, The National Cancer Institute of Canada, and the Gray Laboratory Cancer Research Trust.
PII: S0360-3016(00)01483-8
© 2001 Elsevier Science Inc. All rights reserved.
« Previous
Next »
International Journal of Radiation Oncology * Biology * Physics
Volume 49, Issue 2
, Pages 345-351
, 1 February 2001
