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International Journal of Radiation Oncology * Biology * Physics
Volume 50, Issue 2
, Pages 343-352
, 1 June 2001
Mucositis reduction by selective elimination of oral flora in irradiated cancers of the head and neck: a placebo-controlled double-blind randomized study
References
-
.
Oral complications of cancer therapy.
In:
Berger A, Portenoy RK, Weissman DE editor. Principles and practice of supportive oncology. Philadelphia, New York: Lippincott-Raven Publishers; 1998;p. 223–236
- . Late effects of radiation therapy in the head and neck region. Int J Radiat Oncol Biol Phys. 1995;31:1141–1164
-
.
Oral health care for the cancer patient.
Oral Oncol Eur J Cancer. 1996;32B:281–292
- EORTC late effects working group. Late effects toxicity scoring (the SOMA scale). Radiother Oncol. 1995;35:11–15
- Time-dose factors in radiotherapy (A review of the human data). Radiother Oncol. 1990;19:219–235
- Accelerated versus conventional fractionation in the postoperative radiation of locally advanced head and neck cancer (Influence of patient tumour proliferation). Radiother Oncol. 1992;25:261–266
-
Interruptions adversely affect local control and survival with hyperfractionated radiation therapy for carcinomas of the upper respiratory and digestive tracts. New evidence of accelerated proliferation from Radiation Therapy Oncology Group protocol 8313.
Cancer. 1992;68:2744–2748
- . Loss of local control with prolongation in radiotherapy. Int J Radiat Oncol Biol Phys. 1992;23:457–467
- Hyperfractionation versus conventional fractionation in oropharyngeal carcinoma (Final analysis of a randomized trial of the EORTC cooperative group of radiotherapy). Radiother Oncol. 1992;25:231–241
- . Repair capacity and kinetics for human mucosa and epithelial tumors in the head and neck (Clinical data on the effect of changing the time interval between multiple fractions per day in radiotherapy). Radiother Oncol. 1996;38:89–101
- Accelerated fractionation (AF) compared to conventional fractionation (CF) improves loco-regional control in the radiotherapy of advanced head and neck cancers (Results of the EORTC 22851 randomized trial). Radiother Oncol. 1997;44:111–121
- Conventional radiotherapy as primary treatment of squamous cell carcinoma of the head and neck. A randomized multicenter study of 5 versus 6 fractions per week—report from the DAHANCA 7 trial (Abstr.). Int J Radiat Oncol Biol Phys. 1997;39:188
- . Applying radiobiological principles to combined modality treatment of head and neck cancer—the time factor. Int J Radiat Oncol Biol Phys. 1997;39:831–836
- Avoidance of treatment interruption (An unrecognized benefit of accelerated radiotherapy in oropharyngeal carcinomas?). Int J Radiat Oncol Biol Phys. 1999;45:41–45
- The effects of sucralfate suspension and diphenhydramine syrup plus kaolin-pectin on radiotherapy-induced mucositis. Oral Surg Oral Med Oral Pathol. 1991;71:288–293
- . Management of oral mucositis during local radiation and systemic chemotherapy (A study of 98 patients). J Prosthet Dent. 1991;66:361–369
-
.
Prevention and management of oral mucositis induced by antineoplastic therapy.
Oncology. 1991;5:11–18
- Protocol for the prevention and treatment of oral sequelae resulting from head and neck radiation therapy. Cancer. 1992;70:2171–2180
-
.
Management of mucositis in oral irradiation.
Clin Oncol. 1996;8:106–111
- . Treatment-induced mucositis (An old problem with new remedies). Br J Cancer. 1998;77:1689–1695
- . Prevention and treatment of chemotherapy- and radiotherapy-induced oral mucositis (A review). Oral Oncol. 1999;35:453–470
- Prevention of oral mucositis in radiation therapy (A controlled study with benzydamine hydrochloride rinse). Int J Radiat Oncol Biol Phys. 1989;16:1571–1575
-
The effect of chlorhexidine and benzydamine mouthwashes on mucositis induced by therapeutic irradiation.
Clin Radiology. 1988;39:291–294
- Effect of chlorhexidine rinsing on the oropharyngeal ecology in patients with head and neck cancer who have irradiation mucositis. Oral Surg Oral Med Oral Pathol. 1989;67:154–161
- Chlorhexidine prophylaxis for chemotherapy- and radiotherapy-induced stomatitis (A randomized double-blind trial). Oral Surg Oral Med Oral Pathol. 1990;69:331–338
- Randomized trial of a chlorhexidine mouthwash for alleviation of radiation-induced mucositis. J Clin Oncol. 1994;12:2630–2633
- . The efficacy of sucralfate suspension in the prevention of oral mucositis due to radiation therapy. Int J Radiat Oncol Biol Phys. 1994;28:693–698
- Sucralfate mouth washing in the prevention of radiation induced mucositis (A placebo-controlled double blind randomized study). Int J Radiat Oncol Biol Phys. 1994;30:177–182
-
.
Effects of sucralfate on mucositis during and following radiotherapy of malignancies in the head and neck region. A double-blind placebo-controlled study.
Acta Oncologica. 1995;34:219–223
- Sucralfate for radiation mucositis (Results of a double-blind randomized trial). Int J Radiat Oncol Biol Phys. 1997;37:275–279
- Does sucralfate reduce the acute side-effects in head and neck cancer treated with radiotherapy? A double-blind randomized trial. Radiother Oncol. 1998;47:149–153
- Sucralfate in the prevention of radiation-induced oral mucositis. J Clin Gastroenterol. 1999;28:40–43
- Oral glutamine to alleviate radiation-induced oral mucositis (A pilot randomized trial). Int J Radiat Oncol Biol Phys. 2000;46:535–539
- Clinical and histopathological evaluation of sucralfate in prevention of oral mucositis induced by radiation therapy in patients with head and neck malignancies. Oral Oncology. 2000;36:116–120
-
.
Colonisation index of the oral cavity (A novel technique for monitoring colonisation defense).
Microbiol Ecol Health and Dis. 1989;2:145–151
- Mucositis prevention by selective elimination of oral flora in irradiated head and neck cancer patients. J Oral Pathol Med. 1990;19:486–489
- Effect of selective elimination of the oral flora on mucositis in irradiated head and neck cancer patients. J Surg Oncol. 1991;46:167–173
- . Do microorganisms play a role in irradiation mucositis?. Eur J Clin Microbiol Infect Dis. 1990;9:861–863
-
.
The role of oral microorganisms in cancer therapy.
Oral Maxillofac Surg Infect. 1992;2:81–84
-
.
Irradiation mucositis (A reappraisal).
Oral Oncol Eur J Cancer. 1993;29B:1–2
-
Topical administration of antimicrobial agents to prevent irradiation mucositis of the oral cavity and oropharynx (A pilot study).
Radiat Oncol Invest. 1995;2:283–290
- The reduction of radiation mucositis by selective decontamination antibiotic pastilles (A placebo-controlled double-blind trial). Br J Cancer. 1996;74:312–317
-
A randomized trial of a nonabsorbable antibiotic lozenge given to alleviate radiation-induced mucositis.
Cancer. 1997;5:2193–2199
- . Mucositis as a biological process (A new hypothesis for the development of chemotherapy-induced stomatotoxicity). Oral Oncol. 1998;34:39–43
- Effect of local application of the antimicrobial peptide IB-367 on the incidence and severity of oral mucositis in hamsters. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;87:544–551
- . Dose fractionation and regeneration for cancer of the oral cavity and oropharynx. Part 2. Normal tissue responses (Acute and late effects). Int J Radiat Oncol Biol Phys. 1990;18:101–111
- . Radiotherapy by multiple fractions per day (MFD) in head and neck cancer (Acute reactions of skin and mucosa). Int J Radiat Oncol Biol Phys. 1990;19:301–311
- A prospective trial of accelerated radiotherapy in the postoperative treatment of high-risk squamous cell carcinoma of the head and neck. Int J Radiat Oncol Biol Phys. 1993;26:13–21
- . Early reactions as dose-limiting factors in radiotherapy. Semin Radiat Oncol. 1994;4:55–67
- Continuous course radiation therapy and concurrent combination chemotherapy for squamous cell head and neck cancer. Am J Clin Oncol. 1994;17:369–373
- Acute reaction parameters for human oropharyngeal mucosa. Radiother Oncol. 1995;35:129–137
- Comparison between normal tissue reactions and local tumor control in head and neck cancer patients treated by definitive radiotherapy. Int J Radiat Oncol Biol Phys. 1996;35:455–462
- Randomized clinical trial on accelerated 7 days per week fractionation in radiotherapy for head and neck cancer. Preliminary report on acute toxicity. Radiother Oncol. 1996;40:137–145
- . Concurrent cisplatin, infusional fluoruracil, and conventionally fractionated radiation therapy in head and neck cancer (Dose-limiting mucosal toxicity). J Clin Oncol. 1991;9:453–463
- A randomised multicentre trial of CHART versus conventional radiotherapy in head and neck cancer. Radiother Oncol. 1997;44:123–136
- A randomised trial of accelerated versus conventional radiotherapy in head and neck cancer. Radiother Oncol. 1997;43:39–46
- . Altered fractionation (Limited by mucosal reactions?). Radiother Oncol. 1999;50:247–260
- Scoring irradiation mucositis in head and neck cancer patients. J Oral Pathol Med. 1989;18:167–171
- Validation of a new scoring system for the assessment of clinical trial research of oral mucositis induced by radiation or chemotherapy. Cancer. 1999;85:2103–2113
- . Cell repopulation and overall treatment time. Int J Radiat Oncol Biol Phys. 1990;19:1071–1075
- Mucosal regeneration during radiotherapy. Radiother Oncol. 1996;41:109–118
- . Tumor response, mucosal reactions and late effects after conventional and hyperfractionated radiotherapy. Radiother Oncol. 1998;47:137–143
- Oropharyngeal colonisation with fungi and gram-negative rods in patients treated with radiotherapy of the head and neck. Br J Oral Maxillofac Surg. 1989;27:334–340
- . Cancer therapy and oral mucositis. An appraisal of drug prophylaxis. Drug Saf. 1993;9:185–195
- Povidone-iodine to prevent mucositis in patients during antineoplastic radiochemotherapy. Dermatology. 1997;195(Suppl. 2):57–61
- Wertigheit der prophylaktischen Mundspüling mit PVP-Iodlösung. Prophylaxe der radiochemotherapeutisch bedingten Mukositis. Strahlenther Onkol. 1998;174:149–155
- Prophylaxis with povidone-iodine against induction of oral mucositis by radiochemotherapy. Support Care Cancer. 1998;6:373–377
- . Smoking and mucosal reactions to radiotherapy. Br J Radiol. 1990;63:554–556
- Therapeutische Beeinflussung der radiogenen oralen Mukositis. Strahlenther Onkol. 1997;173:183–192
- . The modifying effect of beta-carotene on radiation and chemotherapy induced oral mucositis. Br J Cancer. 1988;57:416–417
- . Treatment for irradiation-induced mucositis. (letter) Lancet. 1989;1:97
- Local benefit of prostaglandin E2 in radiochemotherapy-induced oral mucositis. Br J Oral Maxillofac Surg. 1990;28:89–91
- Prophylaxis of oral mucositis associated with chemoradiotherapy for oral carcinoma by Azelastine hydrochloride (Azelastine) with other antioxidants. Head Neck. 1994;16:331–339
- Corticosteroids and radiation mucositis in head and neck cancer. A double-blind placebo-controlled randomized trial. Radiother Oncol. 1997;47:145–148
- Can prophylactic application of immunoglobulin decrease radiotherapy-induced oral mucositis?. Am J Clin Oncol. 1997;20:407–411
- Mucosa-adhesive water-soluble polymer film for treatment of acute radiation-induced oral mucositis. Int J Radiat Oncol Biol Phys. 1998;40:1033–1037
- Acute mucositis in the stimulated oral mucosa of patients during radiotherapy for head and neck cancer. Radiother Oncol. 1991;22:7–11
- Effects of stimulated repopulation on oral mucositis during conventional radiotherapy. Radiother Oncol. 1995;37:100–107
- . Assessment of epidermal growth factor in oral secretions of patients receiving radiation therapy for cancer. Oral Oncol. 1997;33:359–363
- . Growth factors (Biological and clinical aspects). Int J Radiat Oncol Biol Phys. 1999;43:877–881
- . Preclinical and early clinical development of keratinocyte growth factor, an epithelial-specific tissue growth factor. Toxicol Pathol. 1999;27:64–71
- . Role of granulocyte macrophage colony stimulating factor in chemoradiotherapy induced oral mucositis. J Clin Oncol. 1996;14:1741–1742
- Efficacy and safety of granulocyte macrophage-colony stimulating factor (GM-CSF) on the frequency and severity of radiation mucositis in patients with head and neck carcinoma. Int J Radiat Oncol Biol Phys. 1997;37:1005–1010
- A pilot study of the effect of granulocyte-macrophage colony-stimulating factor on oral mucositis in head and neck cancer patients during X-radiation therapy (A preliminary report). Int J Radiat Oncol Biol Phys. 1998;42:551–556
- Treatment of irradiation-induced mucositis with growth factors (rhGM-CSF) in patients with head and neck cancer. Anticancer Res. 1999;19:799–804
-
Oral administration of recombinant human granulocyte macrophage colony-stimulating factor in the management of radiotherapy-induced esophagitis.
Clinical Cancer Research. 1999;5:3970–3976
- Granulocyte macrophage-colony stimulating factor (GM-CSF) and sucralfate in prevention of radiation-induced mucositis (A prospective randomized study). Int J Radiat Oncol Biol Phys. 2000;46:525–534
- . The sulfhydryl containing compounds WR-2721 and glutathione as radio- and chemoprotective agents. A review, indications for use and prospects. Br J Cancer. 1999;80:629–638
- . Selective cytoprotection with amifostine in concurrent radiochemotherapy for head and neck cancer. Ann Oncol. 1998;9:505–509
- . Radiochemotherapy with amifostine cytoprotection for head and neck cancer. Support Care Cancer. 1998;6:155–160
- . Preliminary results of a pilot study using WR-2721 before fractionated irradiation of the head and neck to reduce salivary dysfunction. Int J Radiat Oncol Biol Phys. 1994;29:747–754
PII: S0360-3016(01)01444-4
© 2001 Elsevier Science Inc. All rights reserved.
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International Journal of Radiation Oncology * Biology * Physics
Volume 50, Issue 2
, Pages 343-352
, 1 June 2001
