International Journal of Radiation Oncology * Biology * Physics
Volume 50, Issue 2 , Pages 367-375 , 1 June 2001

The role of postradiotherapy neck dissection in supraglottic carcinoma

Presented at the 39th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, October 18–23, 1997, Orlando, FL.

  • Annie W Chan, M.D.

      Affiliations

    • Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    • Corresponding Author InformationReprint requests to: Dr. Annie Chan, Department of Radiation Oncology, Massachusetts General Hospital, 55 Fruit Street, Cox 302, Boston, MA 02114
  • ,
  • Marek Ancukiewicz, Ph.D.

      Affiliations

    • Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
  • ,
  • Natalia Carballo, M.D.

      Affiliations

    • Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
  • ,
  • William Montgomery, M.D.

      Affiliations

    • Department of Otolaryngology, Massachusetts Eye and Ear Infirmary; Harvard Medical School, Boston, MA, USA
  • ,
  • C.C Wang, M.D.

      Affiliations

    • Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

,Accepted 21 December 1999.

References 

  1. Cooper JS, Farnan NC, Asbell SO, et al.  Recursive partitioning analysis of 2105 patients treated in Radiation Therapy Oncology Group studies of head and neck cancer. Cancer. 1996;77:1905–1911
  2. Cerezo L, Millan I, Torre A, et al.  Prognostic factors for survival and tumor control in cervical lymph node metastasis from head and neck cancer. Cancer. 1992;69:1224–1234
  3. Boyd TS, Harari PM, Tannehill SP, et al.  Planned postradiotherapy neck dissection in patients with advanced head and neck cancer. Head Neck. 1998;20(2):132–137
  4. Lee HJ, Zelefsky MJ, Kraus DH, et al.  Long-term regional control after radiation therapy and neck dissection for base of tongue carcinoma. Int J Radiat Oncol Biol Phy. 1997;38(5):995–1000
  5. Parsons JT, Mendenhall WM, Cassisi NJ, et al.  Neck dissection after twice-a-day radiotherapy (Morbidity and relapse rates). Head Neck Surg. 1989;11:400–404
  6. Mendenhall WM, Million RR, Cassisi NJ. Squamous cell carcinoma of the head and neck treated with radiation therapy (The role of neck dissection for clinically positive neck nodes). Int J Radiat Oncol Biol Phy. 1986;12:733–740
  7. Mendenhall WM, Amdur RJ, Stringer SP, et al.  Radiation therapy for squamous cell carcinoma of the tonsillar region (A preferred alternative to surgery?). J Clin Oncol. 2000;18:2219–2225
  8. Mendenhall WM, Stringer SP, Amdur RJ, et al.  Is radiation therapy a preferred alternative to surgery for squamous cell carcinoma of the base of tongue?. J Clin Oncol. 2000;18:35
  9. Johnson CR, Silverman LN, Clay LB, et al.  Radiotherapeutic management of bulky cervical lymphadenopathy in squamous cell carcinoma of the head and neck (Is postradiotherapy neck dissection necessary?). Radiat Oncol Investig. 1998;6(1):52–57
  10. Peters LJ, Weber RS, Morrison WH, et al.  Neck surgery in patients with primary oropharyngeal cancer treated by radiotherapy. Head Neck. 1996;18(6):552–5599
  11. Mabanta SR, Mendenhall WM, Stringer SP, et al.  Salvage treatment for neck recurrence after irradiation alone for head and neck squamous cell carcinoma with clinically positive neck nodes. Head & Neck. 1999;21(7):591–594
  12. Bataini JP, Bernier J, Jaulerry C, et al.  Impact of neck node radioresponsiveness on the regional control probability in patients with oropharynx and pharyngolarynx cancers managed by definitive radiotherapy. Int J Radiat Oncol Biol Phys. 1987;13:817–824
  13. Bernier J, Bataini JP. Regional outcome in oropharyngeal and laryngopharyngeal cancer treated with high dose per fraction radiotherapy (Analysis of neck disease response in 1646 cases). Radiother Oncol. 1986;6:87–103
  14. Bartelink H, Breur K, Hart G. Radiotherapy of lymph node metastasis in patients with squamous cell carcinoma of the head and neck region. Int J Radiat Oncol Biol Phys. 1982;8:983–989
  15. Narayan K, Crane CH, Kleid S, et al.  Planned neck dissection as an adjunct to the management of patients with advanced neck disease treated with definitive radiotherapy (For some or for all?). Head Neck. 1999;21:606–613
  16. American Joint Committee on Cancer. Manual for staging of cancer, 5th ed. Philadelphia, PA: Lippincott Co; 1997. p. 41–46.
  17. Nakfoor BM, Spiro IJ, Wang CC, et al.  Results of accelerated radiotherapy for supraglottic carcinoma (A Massachusetts General Hospital and Massachusetts Eye and Ear Infirmary Experience). Head Neck. 1998;20:379–384
  18. Wang CC, Suit HD, Blitzer PH. Twice-a-day radiation therapy for supraglottic carcinoma. Int J Radiat Oncol Biol Phy. 1985;12:3–7
  19. Wang CC, Nakfoor BM, Spiro IR, et al.  Role of accelerated fractionated irradiation for supraglottic carcinoma (Assessment of results). Cancer J Sci Am. 1997;3:88–91
  20. Wang CC. Radiation therapy for head and neck neoplasm. 3rd ed. New York, NY: Wiley-Liss Co; 1997. p. 240–249.
  21. Cox JD, Stetz J, Pajak TF. Toxicity criteria of the radiation the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC). Int J Radiat Oncol Biol Phys. 1995;31:1341–1346
  22. Overgaard J, Hansen HS, Jorgensen K, et al.  Primary radiotherapy of larynx and pharynx carcinoma—An analysis of some factors influencing local control and survival. Int J Radiat Oncol Biol Phys. 1986;12:515–521
  23. Overgaard J, Hansen HS, Overgaard M, et al.  A randomized double-blind Phase III study of nimorazole as a hypoxic radiosensitizer of primary radiotherapy in supraglottic larynx and pharynx carcinoma. Results of the Danish Head and Neck Cancer Study (DAHANCA) Protocol 5-85. Radiother Oncol. 1998;46(2):135–146
  24. Carl J, Andersen LJ, Pedersen M, et al.  Prognostic factors of local control after radiotherapy in T1 glottic and supraglottic carcinoma of the larynx. Radiother Oncol. 1996;39(3):229–233
  25. Maciejewski B. Regression rate of metastatic neck lymph nodes after radiation treatment as a prognostic factor for local control. Radiother Oncol. 1987;8:301–308
  26. Suit H, Lindberg R, Fletcher GH. Prognostic significance of extent of tumor regression at completion of radiation therapy. Radiology. 1965;84:1100–1107

PII: S0360-3016(01)01468-7

International Journal of Radiation Oncology * Biology * Physics
Volume 50, Issue 2 , Pages 367-375 , 1 June 2001