International Journal of Radiation Oncology * Biology * Physics
Volume 51, Issue 3 , Pages 605-613, 1 November 2001

Phase I/II trial evaluating combined radiotherapy and in situ gene therapy with or without hormonal therapy in the treatment of prostate cancer—A preliminary report

Presented at ASTRO’s 42nd Annual Meeting, 22–26 October, 2000, Boston, Massachusetts.

  • Bin S. Teh, M.D.

      Affiliations

    • Department of Radiology/Section of Radiation Oncology, Houston, TX, USA
  • ,
  • Estuardo Aguilar-Cordova, Ph.D.

      Affiliations

    • Department of Radiology/Section of Radiation Oncology, Houston, TX, USA
    • Department of Cell Biology and Gene Therapy, Houston, TX, USA
  • ,
  • Kenneth Kernen, M.D.

      Affiliations

    • Department of Urology, Houston, TX, USA
  • ,
  • Chieng-Chung Chou, M.D.

      Affiliations

    • Department of Radiology/Section of Radiation Oncology, Houston, TX, USA
  • ,
  • Moshe Shalev, M.D.

      Affiliations

    • Department of Urology, Houston, TX, USA
  • ,
  • Maria T. Vlachaki, M.D.

      Affiliations

    • Department of Radiology/Section of Radiation Oncology, Houston, TX, USA
  • ,
  • Brian Miles, M.D.

      Affiliations

    • Department of Urology, Houston, TX, USA
  • ,
  • Dov Kadmon, M.D.

      Affiliations

    • Department of Urology, Houston, TX, USA
  • ,
  • Wei-Yuan Mai, M.D.

      Affiliations

    • Department of Radiology/Section of Radiation Oncology, Houston, TX, USA
  • ,
  • James Caillouet, R.T.T.

      Affiliations

    • Department of Radiation Therapy, The Methodist Hospital, Houston, TX, USA
  • ,
  • Maria Davis, R.N.

      Affiliations

    • Department of Radiation Therapy, The Methodist Hospital, Houston, TX, USA
  • ,
  • Gustavo Ayala, M.D.

      Affiliations

    • Department of Pathology, Baylor College of Medicine, Houston, TX, USA
  • ,
  • Thomas Wheeler, M.D.

      Affiliations

    • Department of Pathology, Baylor College of Medicine, Houston, TX, USA
  • ,
  • Jett Brady, M.D.

      Affiliations

    • Department of Radiology/Section of Radiation Oncology, Houston, TX, USA
  • ,
  • L.Steve Carpenter, M.D.

      Affiliations

    • Department of Radiology/Section of Radiation Oncology, Houston, TX, USA
  • ,
  • Hsin H. Lu, M.D.

      Affiliations

    • Department of Radiology/Section of Radiation Oncology, Houston, TX, USA
  • ,
  • J.Kam Chiu, M.D.

      Affiliations

    • Department of Radiology/Section of Radiation Oncology, Houston, TX, USA
  • ,
  • Shiao Y. Woo, M.D.

      Affiliations

    • Department of Radiology/Section of Radiation Oncology, Houston, TX, USA
  • ,
  • Timothy Thompson, Ph.D.

      Affiliations

    • Department of Radiology/Section of Radiation Oncology, Houston, TX, USA
    • Department of Cell Biology and Gene Therapy, Houston, TX, USA
    • Department of Urology, Houston, TX, USA
  • ,
  • E.Brian Butler, M.D.

      Affiliations

    • Department of Radiology/Section of Radiation Oncology, Houston, TX, USA
    • Some of the authors have moved prior to the publication of this paper. Their current affiliations are as follows: Estuardo Aguilar-Cordova, Ph.D.—Gene Therapy Initiative, Harvard Medical School, Boston, MA; Kenneth M. Kernen, M.D.—Michigan Institute of Urology, Detroit, MI; Chieng-Chung Chou, M.D.—Chang Gung University and Memorial Hospital, Taiwan; and Moshe Shalev, M.D.—Dept. of Urology, Meir General Hospital, Kfar-Saba, Israel.
    • Corresponding Author InformationReprint requests to: E. Brian Butler, M.D., The Methodist Hospital Radiation Therapy Department, 6565 Fannin, MS 121-B, Houston, TX 77030. Tel: (713) 790-2637; Fax: (713) 793-1300

Received 13 December 2000; received in revised form 14 May 2001; accepted 19 May 2001.

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 This work was supported by a Specialized Program of Research Excellence (SPORE) grant (CA58204) from the National Cancer Institute, the Methodist Hospital Foundation, the General Clinical Research Center (GCRC), Advantagene, Glaxo-Welcome, and Schering Oncology.

PII: S0360-3016(01)01692-3

doi:10.1016/S0360-3016(01)01692-3

International Journal of Radiation Oncology * Biology * Physics
Volume 51, Issue 3 , Pages 605-613, 1 November 2001