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International Journal of Radiation Oncology * Biology * Physics
Volume 53, Issue 2
, Pages 385-393
, 1 June 2002
Altered proliferation and differentiation of human epidermis in cases of skin fibrosis after radiotherapy
References
- . Pathophysiology of irradiated skin and breast. Int J Radiat Oncol Biol Phys. 1995;31:1171–1185
- . Cellular basis of radiation-induced fibrosis. Radiother Oncol. 1995;35:83–90
- Normal tissue radiobiology (From the laboratory to the clinic). Int J Radiat Oncol Biol Phys. 2001;49:353–365
-
.
Immunohistochemical characterization of human gamma-irradiated skin.
Bull Cancer Radiother. 1993;80:126–134
- . Epidermal regulation of dermal fibroblast activity. Plast Reconstr Surg. 1998;102:135–139
- Keratinocyte growth factor as a cytokine that mediates mesenchymal-epithelial interaction. EXS. 1995;74:191–214
- . Growth factors in skin wound healing. Eur J Cell Biol. 1995;68:1–7
- Histopathological and cellular studies of a case of cutaneous radiation syndrome after accidental chronic exposure to a cesium source. Radiat Res. 1999;152:332–337
- . Keratins and the skin. Annu Rev Cell Dev Biol. 1995;11:123–153
- Immunohistochemical localization of proliferating cell nuclear antigen/cyclin in human skin. Arch Dermatol Res. 1992;284:86–91
-
.
Subcellular biochemistry, intermediate filaments. New York: Plenum Press; 1998;
-
.
Expression and function of the keratinocyte integrins.
Dev Suppl. 1993;49:185–192
- . The epidermis (Rising to the surface). Curr Opin Genet Dev. 1994;4:725–736
- . TGF-β1 and radiation fibrosis (A master switch and a specific therapeutic target?). Int J Radiat Oncol Biol Phys. 2000;47:277–290
- Coactivation of AP-1 activity and TGF-beta1 gene expression in the stress response of normal skin cells to ionizing radiation. Oncogene. 1997;15:981–989
- The radiation accident in Georgia (Clinical appearance and diagnosis of cutaneous radiation syndrome). J Am Acad Dermatol. 2000;42:453–458
- . The skin (Its structure and response to ionizing radiation). Int J Radiat Biol. 1990;57:751–773
- . TGF-beta stimulation and inhibition of cell proliferation (New mechanistic insights). Cell. 1990;63:245–247
- . Transforming growth factor-beta and cancer (A love-hate relationship?). Oncol Res. 1997;9:447–457
- Alteration of transforming growth factor-β1 response involves down-regulation of Smad3 signaling in myofibroblasts from skin fibrosis. Am J Pathol. 2001;159:263–272
- . Towards a molecular definition of keratinocyte activation after acute injury to stratified epithelia. Biochem Biophys Res Commun. 1997;236:231–238
- Keratins (K16 and K17) as markers of keratinocyte hyperproliferation in psoriasis in vivo and in vitro. Br J Dermatol. 1995;133:501–511
- Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation. J Cell Biol. 1988;107:427–446
- Activated keratinocytes in the epidermis of hypertrophic scars. Am J Pathol. 1998;152:1133–1141
- TGF beta promotes the basal phenotype of epidermal keratinocytes (Transcriptional induction of K5 and K14 keratin genes). Growth Factors. 1995;12:87–97
- Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis. J Clin Invest. 1992;89:1892–1901
-
.
Changes in keratinocyte differentiation during accelerated repopulation of the irradiated mouse epidermis.
Int J Radiat Oncol Biol Phys. 1996;69:763–769
- Successful treatment of radiation-induced fibrosis using Cu/Zn-SOD and Mn-SOD (An experimental study). Int J Radiat Oncol Biol Phys. 1996;35:305–312
- Antifibrotic action of Cu/Zn SOD is mediated by TGF-beta1 repression and phenotypic reversion of myofibroblasts. Free Radic Biol Med. 2001;30:30–42
- . Striking regression of chronic radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherol. J Clin Oncol. 1999;17:3283–3290
☆ Supported by CEE research Grant FI4P-CT95-0029, by the Comité de Radioprotection d’Electricité de France and by thesis grants from CIFRE/Oxykin Therapeutics and from the Ligue Contre le Cancer.
PII: S0360-3016(01)02732-8
© 2002 Elsevier Science Inc. All rights reserved.
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International Journal of Radiation Oncology * Biology * Physics
Volume 53, Issue 2
, Pages 385-393
, 1 June 2002
