International Journal of Radiation Oncology * Biology * Physics
Volume 59, Issue 2 , Pages 426-435 , 1 June 2004

Localization of neurovascular bundles on pelvic CT and evaluation of radiation dose to structures putatively involved in erectile dysfunction after prostate brachytherapy

The abstract for this article was previously presented at the American Brachytherapy Society annual meeting, May 7–9, 2003, in New York, New York.

  • Jean L. Wright, M.D.

      Affiliations

    • Department of Radiation Oncology, College of Physicians and Surgeons of Columbia University, New York, New York, USA
    • ,
  • Jeffrey H. Newhouse, M.D.

      Affiliations

    • Department of Radiology, College of Physicians and Surgeons of Columbia University, New York, NY, USA
    • ,
  • Joseph L. Laguna, C.M.D.

      Affiliations

    • Department of Radiation Oncology, College of Physicians and Surgeons of Columbia University, New York, New York, USA
    • ,
  • Darleen Vecchio, M.S.

      Affiliations

    • Department of Radiation Oncology, College of Physicians and Surgeons of Columbia University, New York, New York, USA
    • Department of Radiation Oncology, College of Physicians and Surgeons of Columbia University, New York, New York, USA
    • ,
  • Ronald D. Ennis, M.D.

      Affiliations

    • Department of Radiation Oncology, College of Physicians and Surgeons of Columbia University, New York, New York, USA
    • Corresponding Author InformationReprint requests to: Ronald D. Ennis, M.D., Department of Radiation Oncology, College of Physicians and Surgeons of Columbia University, 622 W. 168th St., BHN-B11, New York, NY 10032, USA. Tel: (212) 305-7997

Received 29 May 2003 ,Revised 6 November 2003 ,Accepted 10 November 2003.

References 

  1. Robinson JW, Moritz S, Fung T. Meta-analysis of rates of erectile function after treatment of localized prostate carcinoma. Int J Radiat Oncol Biol Phys. 2002;54:1055–1062
  2. Zelefsky MJ, Eid JF. Elucidating the etiology of erectile dysfunction after definitive therapy for prostatic cancer. Int J Radiat Oncol Biol Phys. 1998;40:129–133
  3. Goldstein I, Feldman MI, Deckers PJ, et al.  Radiation-associated impotence. JAMA. 1984;251:903–910
  4. Incrocci L, Slob AK, Levendag PC. Sexual (dys)function after radiotherapy for prostate cancer (A review). Int J Radiat Oncol Biol Phys. 2002;52:681–693
  5. Lepor H, Gregerman M, Crosby R. Precise localization of the autonomic nerves from the pelvic plexus to the corpora cavernosas (A detailed anatomical study of the adult male pelvis). J Urol. 1985;133:207–212
  6. Wallner KE, Merrick GS, Benson ML, et al.  Penile bulb imaging. Int J Radiat Oncol Biol Phys. 2002;53:928–933
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  8. Talcott JA, Rieker P, Clark JA, et al.  Patient-reported symptoms after primary therapy for early prostate cancer (Results of a prospective cohort study). J Clin Oncol. 1998;16:275–283
  9. Fransson P, Widmark A. Late side effects unchanged 4–8 years after radiotherapy for prostate carcinoma (A comparison with age-matched controls). Cancer. 1999;85:678–688
  10. DiBiase SJ, Wallner K, Tralins K, et al.  Brachytherapy radiation doses to the neurovascular bundles. Int J Radiat Oncol Biol Phys. 2000;46:1301–1307
  11. Merrick GS, Butler WM, Dorsey AT, Lief JH, Donzella JG. A comparison of radiation dose to the neurovascular bundles in men with and without prostate brachytherapy-induced erectile dysfunction. Int J Radiat Oncol Biol Phys. 2000;48:1069–1074
  12. Carrier S, Hricak H, Lee SS. Radiation-induced decrease in nitric oxide synthase-containing nerves in the rat penis. Radiology. 1995;195:95–99
  13. Pickett B, Fisch BM, Weinberg V, et al. Dose to the bulb of the penis is associated with the risk of impotence following radiotherapy for prostate cancer. Int J Radiat Oncol Biol Phys 1999;45:Suppl. 263 (Abstr.)
  14. Fisch BM, Pickett B, Weinberg V, et al.  Dose of radiation received by the bulb of the penis correlates with risk of impotence after three-dimensional conformal radiotherapy for prostate cancer. Urology. 2001;57:955–959
  15. Merrick GS, Wallner K, Butler WM, et al.  A comparison of radiation dose to the bulb of the penis in men with and without prostate brachytherapy-induced erectile dysfunction. Int J Radiat Oncol Biol Phys. 2001;50:597–604
  16. Merrick GS, Butler WM, Wallner KE, et al.  The importance of radiation doses to the penile bulb vs. crura in the development of postbrachytherapy erectile dysfunction. Int J Radiat Oncol Biol Phys. 2002;54:1055–1062
  17. Mulhall JP, Yanover PM. Correlation of radiation dose and impotence risk after three-dimensional conformal radiotherapy for prostate cancer. Urology. 2001;58:828

PII: S0360-3016(03)02317-4

doi: 10.1016/j.ijrobp.2003.11.022

International Journal of Radiation Oncology * Biology * Physics
Volume 59, Issue 2 , Pages 426-435 , 1 June 2004

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