International Journal of Radiation Oncology * Biology * Physics
Volume 60, Issue 3 , Pages 909-919 , 1 November 2004

In vivo determination of tumor oxygenation during growth and in response to carbogen breathing using 15C5-loaded alginate capsules as fluorine-19 magnetic resonance imaging oxygen sensors

This work was presented in part at the ISMRM–ESMRMB 2001 Joint Annual Meeting, in Glasgow, Scotland.

  • Ulrike Nöth, Ph.D.

      Affiliations

    • Cancer Research UK Biomedical Magnetic Resonance Research Group, Department of Basic Medical Sciences, St. George's Hospital Medical School, London, United Kingdom
    • Corresponding Author InformationReprint requests to: Ulrike Nöth, Ph.D., Wellcome Department of Imaging Neuroscience, Institute of Neurology, UCL, 12 Queen Square, London WC1N 3BG, United Kingdom. Tel: (+44) 20-7833-7488; Fax: (+44) 20-7813-1420
  • ,
  • Loreta M. Rodrigues, M.Sc.

      Affiliations

    • Cancer Research UK Biomedical Magnetic Resonance Research Group, Department of Basic Medical Sciences, St. George's Hospital Medical School, London, United Kingdom
  • ,
  • Simon P. Robinson, Ph.D.

      Affiliations

    • Cancer Research UK Biomedical Magnetic Resonance Research Group, Department of Basic Medical Sciences, St. George's Hospital Medical School, London, United Kingdom
  • ,
  • Anette Jork, Ph.D.

      Affiliations

    • Department of Biotechnology, University of Würzburg, Würzburg, Germany
  • ,
  • Ulrich Zimmermann, Ph.D.

      Affiliations

    • Department of Biotechnology, University of Würzburg, Würzburg, Germany
  • ,
  • Barry Newell, M.B.B.S., M.R.C.P.

      Affiliations

    • Farnborough Hospital, Farnborough Common, Orpington, Kent, United Kingdom
  • ,
  • John R. Griffiths, M.B.B.S., D.Phil.

      Affiliations

    • Cancer Research UK Biomedical Magnetic Resonance Research Group, Department of Basic Medical Sciences, St. George's Hospital Medical School, London, United Kingdom

Received 29 May 2003 ,Revised 28 June 2004 ,Accepted 7 July 2004.

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 This work was supported by the Deutsche Forschungsgemeinschaft (NO395/1-1, to Dr. Noth; ZI99/15-1, to Dr. Zimmerman), the Bundesministerium fuer Bildung und Forschung (0311588, to Dr. Zimmermann) and Cancer Research UK [CRC] Grant C12/A1209. Doctor Robinson is the recipient of a Royal Society University Research Fellowship.

PII: S0360-3016(04)02008-5

doi: 10.1016/j.ijrobp.2004.07.671

International Journal of Radiation Oncology * Biology * Physics
Volume 60, Issue 3 , Pages 909-919 , 1 November 2004