International Journal of Radiation Oncology * Biology * Physics
Volume 62, Issue 2 , Pages 501-507 , 1 June 2005

Nasopharyngeal carcinoma staging by (18)F-fluorodeoxyglucose positron emission tomography

  • Joseph Tung-Chieh Chang, M.D., M.H.A.

      Affiliations

    • Department of Radiation Oncology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    • Taipei Chang Gung Head and Neck Oncology Group, Chang Gung Memorial Hospital, Taoyuan, Taiwan
  • ,
  • Sheng-Chieh Chan, M.D.

      Affiliations

    • Taipei Chang Gung Head and Neck Oncology Group, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    • Department of Nuclear Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan
  • ,
  • Tzu-Chen Yen, M.D., Ph.D.

      Affiliations

    • Taipei Chang Gung Head and Neck Oncology Group, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    • Department of Nuclear Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan
  • ,
  • Chun-Ta Liao, M.D.

      Affiliations

    • Taipei Chang Gung Head and Neck Oncology Group, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    • Department of Ear Nose and Throat, Chang Gung Memorial Hospital, Taoyuan, Taiwan
  • ,
  • Chien-Yu Lin, M.D.

      Affiliations

    • Department of Radiation Oncology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    • Taipei Chang Gung Head and Neck Oncology Group, Chang Gung Memorial Hospital, Taoyuan, Taiwan
  • ,
  • Kun-Ju Lin, M.D., Ph.D.

      Affiliations

    • Taipei Chang Gung Head and Neck Oncology Group, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    • Department of Nuclear Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan
  • ,
  • I.-How Chen, M.D.

      Affiliations

    • Taipei Chang Gung Head and Neck Oncology Group, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    • Department of Ear Nose and Throat, Chang Gung Memorial Hospital, Taoyuan, Taiwan
  • ,
  • Hung-Ming Wang, M.D.

      Affiliations

    • Taipei Chang Gung Head and Neck Oncology Group, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    • Department of Hematology/Oncology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
  • ,
  • Yu-Chen Chang, M.D.

      Affiliations

    • Taipei Chang Gung Head and Neck Oncology Group, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    • Department of Nuclear Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan
  • ,
  • Tsung-Ming Chen, M.D.

      Affiliations

    • Taipei Chang Gung Head and Neck Oncology Group, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    • Department of Ear Nose and Throat, Chang Gung Memorial Hospital, Taoyuan, Taiwan
  • ,
  • Chung-Jan Kang, M.D.

      Affiliations

    • Taipei Chang Gung Head and Neck Oncology Group, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    • Department of Ear Nose and Throat, Chang Gung Memorial Hospital, Taoyuan, Taiwan
  • ,
  • Shu-Hang Ng, M.D.

      Affiliations

    • Taipei Chang Gung Head and Neck Oncology Group, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    • Department of First Radiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    • Corresponding Author InformationReprint requests to: Shun-Hang Ng, M.D., Department of First Radiology, Chang Gung Memorial Hospital, 5 Fu-Shin St., Taoyuan 333 Taiwan. Tel: (+886)-3-211-8247; Fax: (+886)-3-211-8247

Received 17 May 2004 ,Revised 17 September 2004 ,Accepted 22 September 2004.

References 

  1. Fandi A , Altrun M , Azli N , et al.   Nasopharyngeal cancer (Epidemiology, staging, and treatment) . Semin Oncol . 1994;21:382–397
  2. Hung SC . Nasopharyngeal cancer (A review of 1605 patients treated radically with cobalt 60) . Int J Radiat Oncol Biol Phys . 1980;6:401–407
  3. Sham JS , Choy D , Choi P . Nasopharyngeal carcinoma (The significance of neck node involvement in relation to the pattern of distant failure) . Br J Radiol . 1990;63:108–113
  4. Vikram B , Mishra UB , Strong EW , et al.   Patterns of failure in carcinoma of the nasopharynx (Failure at distant sites) . Head Neck Surg . 1986;8:276–279
  5. Zhang EP , Lian PG , Cai KL , et al.   Radiation therapy of nasopharyngeal carcinoma (Prognostic factors based on a 10-year follow-up of 1302 patients) . Int J Radiat Oncol Biol Phys . 1989;16:301–305
  6. Teo PM , Kwan WH , Lee WY , et al.   Prognosticators determining survival subsequent to distant metastasis from nasopharyngeal carcinoma . Cancer . 1996;77:2423–2431
  7. Tang SGJ , Lin FJ , Chen MS , et al.   Prognostic factors of nasopharyngeal carcinoma (A multivariate analysis) . Int J Radiat Oncol Biol Phys . 1990;19:1143–1149
  8. Lee AWM , Poon YF , Foo W , et al.   Retrospective analysis of 5037 patients with nasopharyngeal carcinoma treated during 1976–1986 (Overall survival and patterns of failure) . Int J Radiat Oncol Biol Phys . 1992;23:261–270
  9. Fandi A , Bachouchi M , Azli N , et al.   Long-term disease free survivors in metastatic undifferentiated carcinoma of nasopharyngeal type . J Clin Oncol . 2000;18:1324–1330
  10. Jerusalem G , Hustinx R , Beguin Y , et al.   PET scan imaging in oncology . Eur J Cancer . 2003;39:1525–1534
  11. Kresnik E , Mikosch P , Gallowitsch HJ , et al.   Evaluation of head and neck cancer with 18F-FDG PET (A comparison with conventional methods) . Eur J Nucl Med . 2001;28:816–821
  12. Teknos TN , Rosenthal EL , Lee D , et al.   Positron emission tomography in the evaluation of stage III and IV head and neck cancer . Head Heck . 2001;23:1056–1060
  13. Anzai Y , Carroll WR , Quint DJ , et al.   Recurrence of head and neck cancer after surgery or irradiation (Prospective comparison of 2-deoxy-2-[F-18]-fluoro-d-glucose PET and MRI imaging diagnoses) . Radiology . 1996;200:135–141
  14. Kao CH , ChangLai SP , Chieng PU , et al.   Detection of recurrent or persistent nasopharyngeal carcinoma after radiotherapy with 18-fluoro-2-deoxyglucose positron emission tomography and comparison with computed tomography . J Clin Oncol . 1998;11:3550–3555
  15. Kubota K , Itoh M , Ozahi K , et al.   Advantage of delayed whole-body FDG-PET imaging for tumour detection . Eur J Nucl Med . 2001;28:696–703
  16. Chang JT , See LC , Tang SG , et al.   The role of brachytherapy in early stage nasopharyngeal carcinoma . Int J Radiat Oncol Biol Phys . 1996;36:1019–1024
  17. Chang JT , See LC , Liao CT , et al.   Locally recurrent nasopharyngeal carcinoma . Radiother Oncol . 2000;54:135–142
  18. Fleming ID , Cooper JS , Henson DE , et al.   American Joint Committee on Cancer AJCC cancer staging manual . 6th ed. New York: Springer; 2002;
  19. Lee N , Xia P , Quivery JM , et al.   Intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma (An update of the UCSF experience) . Int J Radiat Oncol Biol Phys . 2002;53:12–22
  20. Perez CA , Devineni VR , Marcial-Vega V , et al.   Carcinoma of the nasopharynx (Factors affecting prognosis) . Int J Radiat Oncol Biol Phys . 1990;23:271–280
  21. Boussen H , Cvitkovic E , Wendling JL , et al.   Chemotherapy of metastatic and/or recurrent undifferentiated nasopharyngeal carcinoma with cisplatin, bleomycin, and fluorouracil . J Clin Oncol . 1991;9:1675–1681
  22. Lin JC , Jan JS , Hsu CY , et al.   Phase III study of concurrent chemoradiotherapy versus radiotherapy alone for advanced nasopharyngeal carcinoma (Positive effect on overall and progression-free survival) . J Clin Oncol . 2003;21:631–637
  23. Chan AT , Teo PM , Ngan PK , et al.   Concurrent chemotherapy-radiotherapy compared with radiotherapy alone in locoregionally advanced nasopharyngeal carcinoma (Progression-free survival analysis of a phase III randomized trial) . J Clin Oncol . 2002;20:2038–2044
  24. Kumar MB , Lu JJ , Loh KS , et al.   Tailoring distant metastatic imaging for patients with clinically localized undifferentiated nasopharyngeal carcinoma . Int J Radiat Oncol Biol Phys . 2004;58:688–693
  25. Choo T , Tannock I . Chemotherapy for recurrent or metastatic carcinoma of the nasopharynx (A review of Princess Margaret Hospital experience) . Cancer . 1991;68:2120–2140
  26. Hong RL , Ting LL , Ko JY , et al.   Induction chemotherapy with mitomycin, epirubicin, cisplatin, fluorouracil, and leucovorin followed by radiotherapy in the treatment of locoregionally advanced nasopharyngeal carcinoma . J Clin Oncol . 2001;19:4305–4313
  27. Siu LL , Czaykowski PM , Tannock IF . Phase I/II study of the CAPABLE regimen for patients with poorly differentiated carcinoma of the nasopharynx . J Clin Oncol . 1998;16:2514–2521
  28. Al-Sarraf M , LeBlanc M , Giri PG , et al.   Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer (Phase III randomized Intergroup study 0099) . J Clin Oncol . 1998;16:1310–1317
  29. Engel H , Steinert H , Buck A , et al.   Whole-body PET (Physiological and artifactual fluorodeoxyglucose accumulations) . J Nucl Med . 1996;73:441–446
  30. Strauss LG . Fluorine-18 deoxyglucose and false positive results (A major problem in the diagnostics of oncological patients) . Eur J Nucl Med . 1996;23:1409–1415
  31. Lardinois D , Weder W , Hany TF , et al.   Staging of non-small-cell cancer with integrated positron-emission tomography and computed tomography . N Engl J Med . 2003;348:2500–2507

 Supported by CMRPG32034 from the Chang Gung Memorial Hospital and University.

PII: S0360-3016(04)02713-0

doi: 10.1016/j.ijrobp.2004.09.057

International Journal of Radiation Oncology * Biology * Physics
Volume 62, Issue 2 , Pages 501-507 , 1 June 2005