International Journal of Radiation Oncology * Biology * Physics
Volume 64, Issue 1 , Pages 47-56 , 1 January 2006

Chemotherapy in locally advanced nasopharyngeal carcinoma: An individual patient data meta-analysis of eight randomized trials and 1753 patients

  • Bertrand Baujat, M.D.

      Affiliations

    • Institut Gustave-Roussy, Villejuif, France
    • ,
  • Hélène Audry, M.Sc.

      Affiliations

    • Institut Gustave-Roussy, Villejuif, France
    • ,
  • Jean Bourhis, M.D., Ph.D.

      Affiliations

    • Institut Gustave-Roussy, Villejuif, France
    • ,
  • Anthony T.C. Chan, M.D.

      Affiliations

    • Department of Clinical Oncology, Prince of Wales Hospital, Hong-Kong, China
    • ,
  • Haluk Onat, M.D.

      Affiliations

    • Istanbul University, Institute of Oncology, Istanbul, Turkey
    • ,
  • Daniel T.T. Chua, M.D.

      Affiliations

    • Department of Clinical Oncology, Queen Mary Hospital, Hong-Kong, China
    • ,
  • Dora L.W. Kwong, M.D.

      Affiliations

    • Department of Clinical Oncology, Queen Mary Hospital, Hong-Kong, China
    • ,
  • Muhyi al-Sarraf, M.D.

      Affiliations

    • Wayne State University, Detroit, MI
    • ,
  • Kwan-Hwa Chi, M.D.

      Affiliations

    • Taiwan Cooperative Oncology Group, Taipei, Taiwan
    • ,
  • Masato Hareyama, M.D.

      Affiliations

    • Department of Radiology, Sapporo Medical University, Sapporo, Japan
    • ,
  • Sing F. Leung, M.D.

      Affiliations

    • Department of Clinical Oncology, Prince of Wales Hospital, Hong-Kong, China
    • ,
  • Kullathorn Thephamongkhol, M.D.

      Affiliations

    • Institut Gustave-Roussy, Villejuif, France
    • ,
  • Jean-Pierre Pignon, M.D., Ph.D.

      Affiliations

    • Institut Gustave-Roussy, Villejuif, France
    • Corresponding Author InformationReprint requests to: Jean-Pierre Pignon, M.D., Ph.D., Service de Biostatistique et d’Epidémiologie, Institut Gustave-Roussy, Villejuif 94805 Cedex France. Tel: (+33) 1-4211-4565; Fax: (+33) 1-4211-5258
    • ,
  • MAC-NPC Collaborative Group

Received 20 May 2005 ,Accepted 20 June 2005.

References 

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  19. Cvitkovic E , Eschwege F , Rahal M , et al.   Preliminary results of trial comparing neoadjuvant chemotherapy (cisplatin, epirubicin, bleomycin) plus radiotherapy vs. radiotherapy alone in Stage IV (≥N2, M0) undifferentiated nasopharyngeal carcinoma (A positive effect on progression free survival) . Int J Radiat Oncol Biol Phys . 1996;35:463–469
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 A complete list of the members of the MAC-NPC Collaborative Group is provided in the Appendix.Supported by the Institut Gustave-Roussy, Aventis, Sanofi-Synthelabo, and Schering-Plough who had no role in the study design, data collection, data analysis, data interpretation, or writing of the report. The authors had full access to all the data and are fully responsible for the decision to submit the paper for publication.

PII: S0360-3016(05)02221-2

doi: 10.1016/j.ijrobp.2005.06.037

International Journal of Radiation Oncology * Biology * Physics
Volume 64, Issue 1 , Pages 47-56 , 1 January 2006

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