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International Journal of Radiation Oncology * Biology * Physics
Volume 64, Issue 1
, Pages 6-12
, 1 January 2006
Pathogenic role of the renin–angiotensin system in modulating radiation-induced late effects
References
- Modulation of radiation injury . Science . 2004;304:693–694
- Effects of radiation on normal tissue (Consequences and mechanisms) . Lancet Oncol . 2003;4:529–536
-
.
The pathobiology of late effects in irradiation
.
In:
Meyn RE
, Withers HR
editor.
Radiation biology in cancer research
. New York: Raven Press; 1980;p. 439–448
- . Clinical radiation pathology as applied to curative radiotherapy . Cancer . 1968;22:767–778
-
Capillary endothelium
(Target site of renal radiation injury)
.
Lab Invest
. 1993;57:551–565
- . Permanent radiation myelopathy . Br J Radiol . 1992;65:737–753
- . Molecular biology mechanisms in the radiation induction of pulmonary injury syndromes (Interrelationship between the alveolar macrophages and the septal fibroblast) . Int J Radiat Oncol Biol Phys . 1992;24:93–101
- . The radiotherapeutic injury—a complex “wound” . Radiother Oncol . 2002;63:129–145
-
Pharmacologic modification of radiation-induced late normal tissue injury
.
In:
Mittal BB
, Purdy JA
, Ang KK
editor.
Radiation therapy
. Norwell, MA: Kluwer; 1998;p. 129–151
- . Modifying normal tissue damage postirradiation . Radiat Res . 2002;157:204–223
- Stress and radiation-induced activation of multiple intracellular signaling pathways . Radiat Res . 2003;159:283–300
- . TGF-β1 and radiation fibrosis (A master switch and a specific therapeutic target?) . Int J Radiat Oncol Biol Phys . 2000;47:277–290
- . Minireview (Overview of the renin-angiotensin system—an endocrine and paracrine system) . Endocrinology . 2003;144:2179–2183
- Molecular cloning of a novel angiotensin II receptor isoform involved in phosphotyrosine phosphatase inhibition . J Biol Chem . 1993;268:24543–24546
- Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven transmembrane receptors . J Biol Chem . 1993;268:24539–24542
-
.
Angiotensin type II receptor stimulation of neuronal K+ currents involves an inhibitory G protein
.
Am J Physiol
. 1994;267:C1289–C1297
- . The AT2 receptor selectively associates with Gia2 and Gia3 in the rat fetus . J Biol Chem . 1996;271:15026–15033
- . The granulocyte-angiotensin system. Angiotensin I-converting enzyme activity of cathepsin G . J Biol Chem . 1982;257:15042–15046
- . Substrate specificity of tonin from rat submaxillary gland . Circ Res . 1976;39:629–632
- High levels of human chymase expression in the pineal and pituitary glands . Brain Res . 1997;752:269–278
- Processing of angiotensin peptides by NG108-15 neuroblastoma x glioma hybrid cell line . Peptides . 1990;11:375–380
- In vivo metabolism of angiotensin I by neutral endopeptidase (EC 3.4.24.11) in spontaneously hypertensive rats . Hypertension . 1992;19:692–696
-
Conversion of angiotensin I to angiotensin-(1-7) by thimet oligopeptidase (EC 3.4.24.15) in vascular smooth muscle cells
.
J Vasc Biol Med
. 1995;5:129–137
-
Production of Ang-(1-7) by human vascular endothelium
.
Hypertension
. 1992;19(Suppl. II):II-56–II-61
- . The brain angiotensin system and extracellular matrix molecules in neural plasticity, learning, and memory . Prog Neurobiol . 2004;72:263–293
-
A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9
.
Circ Res
. 2000;87:E1–E9
- A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase . J Biol Chem . 2000;275:33238–33243
- ACE2, a new regulator of the renin-angiotensin system . Trends Endocrinol Metab . 2004;15:166–169
- Novel aspects of the renal renin-angiotensin system (Angiotensin-(1-7), ACE2 and blood pressure regulation) . Contrib Nephrol . 2004;143:77–89
- . Physiology and pathophysiology of the adipose tissue renin-angiotensin system . Hypertension . 2000;35:1270–1277
- . Physiological genomic analysis of the brain renin-angiotensin system . Am J Physiol Regul Integr Comp Physiol . 2003;285:R498–R511
- Tissue renin-angiotensinogen systems (New insights from experimental animal models in hypertension research) . J Mol Med . 2001;79:76–102
- . The intrarenal renin angiotensin . Curr Opin Nephrol Hypertens . 1993;2:41–44
- . The renin-angiotensin system and the exocrine pancreas . JOP . 2001;2:33–39
- . Angiotensin II (A reproductive hormone too?) . Regul Pept . 1999;79:25–40
- . The uteroplacental renin-angiotensin system . Placenta . 2000;21:468–477
-
.
Overview of the angiotensin-converting enzyme inhibitors
.
Am J Health Syst Pharm
. 2000;57:S3–S7
- Protective effect of the inhibition of the renin-angiotensin system on aging . Regul Pept . 2005;128:247–252
- Divergent regulation of circulation and intra-renal renin-angiotensin systems in response to long-term blockade . Am J Nephrol . 2005;25:335–341
- Does the angiotensin II receptor antagonist losartan improve cognitive function? . Drugs Aging . 2002;19:723–732
-
Differential regulation of circulating and intra-renal renin-angiotensin systems and improved metabolic function in Fisher 344 rats after long-term AT1 receptor blockade
.
Hypertension
. 2005;46:818
-
Effects of chronic AT1 receptor blockade on blood pressure, insulin, leptin and body weight in Fisher 344 rats one year post-whole brain irradiation
.
Hypertension
. 2005;46:831
- . Radiation nephropathy . Semin Nephrol . 2003;23:486–499
- . Physiological factors affecting renal radiation tolerance (A guide to the treatment of late effects) . Br J Cancer . 1986;53(Suppl. VII):265–267
- . Treatment of radiation nephropathy with captopril . Radiat Res . 1992;132:346–350
- Prophylaxis of bone marrow transplant nephropathy with captopril, an inhibitor of angiotensin-converting enzyme . Radiat Res . 1993;136:404–407
- . Treatment of radiation nephropathy with ACE inhibitors . Int J Radiat Oncol Biol Phys . 1993;27:93–99
- . Amelioration of radiation nephropathy in rats by postirradiation treatment with dexamethasone and/or captopril . Radiat Res . 1995;143:58–68
- Long-term enalapril and hydrochlorothiazide in radiation nephritis . Nephron . 1993;64:249–255
- . Radiation nephropathy is treatable with an angiotensin converting enzyme inhibitor or an angiotensin II type-1 (AT1) receptor antagonist . Radiother Oncol . 1998;46:307–315
- Prophylaxis of experimental bone marrow transplant nephropathy . J Lab Clin Med . 1994;124:371–380
- . Noncontinuous use of angiotensin converting enzyme inhibitors in the treatment of experimental bone marrow transplant nephropathy . Bone Marrow Transplant . 1997;19:729–735
- . Successful brief captopril treatment in experimental radiation nephropathy . J Lab Clin Med . 1997;129:536–547
- Angiotensin II receptor antagonists in the prevention of radiation nephropathy . Radiat Res . 1996;146:106–110
- . ACE inhibitors and AII receptor antagonists in the treatment and prevention of bone marrow transplant nephropathy . Curr Pharm Des . 2003;9:737–749
- . Successful treatment of radiation nephropathy with angiotensin II blockade . Int J Radiat Oncol Biol Phys . 2003;55:190–193
- Angiotensin II receptor antagonists (A new approach to blockade of the renin-angiotensin system) . Am Heart J . 1994;127:1388–1401
- . Angiotensin II infusion exacerbates radiation nephropathy . J Lab Clin Med . 1999;134:283–291
- Radiation nephropathy in mature pigs following irradiation of both kidneys . Int J Radiat Biol . 1989;56:83–98
- . The renin-angiotensin system in experimental radiation nephropathy . J Lab Clin Med . 2002;139:251–257
- . Impact of angiotensin type 2 receptor blockade on experimental radiation nephropathy . Radiat Res . 2004;161:312–317
- Radiation-induced lung injury . Semin Radiat Oncol . 2003;13:333–345
-
Prevention of pulmonary vascular changes of chronic alveolar hypoxia by inhibition of angiotensin-1-converting enzyme in the rat
.
Lab Invest
. 1975;38:57–61
- Monocrotaline-induced pulmonary fibrosis in rats (Amelioration by captopril and penicillamine) . Proc Soc Exp Biol Med . 1985;180:112–120
- Radiation-induced pulmonary endothelial dysfunction in rats (Modification by an inhibitor of angiotensin converting enzyme) . Int J Radiat Oncol Biol Phys . 1988;15:135–140
- Captopril reduces collagen and mast cell accumulation in irradiated rat lung . Int J Radiat Oncol Biol Phys . 1990;19:1405–1409
- Radiation pneumotoxicity in rats (Modification by inhibitors of angiotensin converting enzyme) . Int J Radiat Oncol Biol Phys . 1992;22:623–625
- Control of radiation-induced pneumopathy and lung fibrosis by angiotensin-converting enzyme inhibitors and an angiotensin II type 1 receptor blocker . Int J Radiat Biol . 2000;76:523–532
- Cancer statistics, 2005 . CA Cancer J Clin . 2005;55:10–30
- . The management of brain metastases . Cancer Treat Rev . 2003;29:533–540
-
.
Central nervous system. Radiation toxicity: A practical guide
. New York: Kluwer Academic Publishers; 2005;
In press
- . Effects of treatment on long-term survivors with malignant astrocytomas . Ann Neurol . 1990;28:818–822
- Neurobehavioral sequelae of cranial irradiation in adults (A review of radiation-induced encephalopathy) . J Clin Oncol . 1994;12:627–642
- Radiological and clinical assessment of long-term brain tumour survivors after radiotherapy . Radiother Oncol . 2003;69:169–176
- An experimental study of radiation-induced cognitive dysfunction in an adult rat model . Br J Radiol . 1999;72:1196–1201
- The renin-angiotensin system in the brain (Possible therapeutic implications for AT1-receptor blockers) . J Hum Hypertens . 2002;16:S64–S70
- The brain renin-angiotensin system (Location and physiological roles) . Int J Biochem Cell Biol . 2003;35:901–918
- . The role of angiotensin II in cognition and behaviour . Eur J Pharmacol . 2002;438:1–14
- . Age-related decline in spatial learning and memory (Attenuation by captopril) . Clin Exp Hypertens . 2003;25:455–474
- Modification of radiation injury by ramipril, inhibitor of angiotensin-converting enzyme, on optic neuropathy in the rat . Radiat Res . 2004;161:137–142
-
Vascular damage after fractionated whole-brain irradiation in rats
.
Radiat Res.
. 2005;
in press
-
Influence of the brain renin-angiotensin system on cognitive ability during aging
.
Hypertension
. 2002;40:381
- Factors controlling growth and matrix production in vascular smooth muscle and glomerular mesangial cells . Curr Opin Nephrol Hypertens . 1997;6:88–105
- . Interactions of transforming growth factor-β and angiotensin II in renal fibrosis . Hypertension . 1998;31:181–188
- Effects and interactions of endothelin-1 and angiotensin II on matrix protein expression and synthesis and mesangial cell growth . Hypertension . 1996;27:885–892
- Dual effects of angiotensin II on the plasminogen/plasmin system in rat mesangial cells . Kidney Int . 1997;51:664–671
-
.
Fibrinolytic balance, the renin-angiotensin system and atherosclerotic disease
.
Eur Heart J
. 1998;19(Suppl. G):G9–G12
- Inflammation and angiotensin II . Int J Biochem Cell Biol . 2003;35:881–900
- . Angiotensin peptides and inducible transcription factors . J Mol Med . 1999;77:339–357
- Anti-stress and anti-anxiety effects of centrally acting angiotensin II AT1 receptor antagonists . Regul Pept . 2005;128:227–238
-
Angiotensin II AT(1) receptor blockade abolishes brain microvascular inflammation and heat shock protein responses in hypertensive rats
.
J Cereb Blood Flow Metab
. 2005;
in press
- . Stress and the inflammatory response (A review of neurogenic inflammation) . Brain Behav Immun . 2002;16:622–653
- . Inflammatory blockade restores adult hippocampal neurogenesis . Science . 2003;302:1760–1765
- Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive deficits in young mice . Exp Neurol . 2004;188:316–330
- NAD(P)H oxidase-derived reactive oxygen species as mediators of angiotensin II signaling . Antioxid Redox Signal . 2002;4:899–914
- Rac1 disrupts p67phox/p47phox binding (A novel role of Rac in NADPH oxidase activation) . Biochem Biophys Res Commun . 1999;263:118–122
- . Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells . J Biol Chem . 2002;277:19952–19960
- . NADPH oxidase (Role in cardiovascular biology and disease) . Circ Res . 2000;86:494–501
- Cellular regulation by hydrogen peroxide . J Am Soc Nephrol . 2003;14(Suppl. 3):S211–S215
- Angiotensin II stimulated NADH and NADPH oxidase activity in cultured vascular smooth muscle cells . Circ Res . 1994;74:1141–1148
- Requirement for Rac1-dependent NADPH oxidase in the cardiovascular and dipsogenic actions of angiotenisn II in the brain . Circ Res . 2004;95:532–539
- . Assembly and activation of the neutrophil NADPH oxidase in granule membranes . Antioxid Redox Signal . 2002;4:49–60
-
Low glial angiotensinogen is not associated with deficits in angiotensin peptides in neuronal pathways in transgenic ASrAogen rats
.
[Abstract]
FASEB J
. 2005;19:A1188
-
Neprilysin and ACE2 regulation during aging in rats with low brain angiotensinogen
.
Hypertension
. 2005;
in press
-
.
Chronic oxidative stress and radiation-induced late normal tissue injury
(A review)
.
Int Radiat Biol
. 2004;80:251–259
- . Are there meaningful differences in blood pressure control with current antihypertensive agents? . Am J Hypertens . 2002;15:14S–21S
- Cytostatic properties of some angiotensin I converting enzyme inhibitors and of angiotensin II type I receptors . Curr Pharm Des . 2003;9:751–761
Supported in part by NIH grants DK51612, CA82722, and HL51952.
PII: S0360-3016(05)02578-2
doi: 10.1016/j.ijrobp.2005.08.033
© 2006 Elsevier Inc. All rights reserved.
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International Journal of Radiation Oncology * Biology * Physics
Volume 64, Issue 1
, Pages 6-12
, 1 January 2006
