International Journal of Radiation Oncology * Biology * Physics
Volume 64, Issue 4 , Pages 981-982 , 15 March 2006

Timing of concurrent radiotherapy and chemotherapy in limited-disease small-cell lung cancer: “Meta-analysis of meta-analyses”

  • Branislav Jeremic, M.D.

      Affiliations

    • Corresponding Author InformationReprint requests to: Branislav Jeremic, M.D., International Atomic Energy Agency-NAHU, Applied Radiation Biology and Radiotherapy Section (ARBR), Division of Human Health, Department of Nuclear Sciences, Wagramer Strasse 5, Vienna A-1400, Austria. Tel: (+43) 1-2600-21666; Fax: (+43) 1-26007-21668

Received 18 July 2005 ,Revised 28 October 2005 ,Accepted 31 October 2005.

References 

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  2. Murray N , Coy  , Pater J , et al.   Importance of timing for thoracic irradiation in the combined modality treatment of limited stage small cell lung cancer . J Clin Oncol . 1993;11:336–344
  3. Jeremic B , Shibamoto Y , Acimovic L , et al.   Initial versus delayed accelerated hyperfractionated radiation therapy and concurrent chemotherapy in limited small cell lung cancer . J Clin Oncol . 1997;15:893–900
  4. Work E , Nielsen O , Bentzen S , et al.   Randomized study of initial versus late chest irradiation combined with chemotherapy in limited-stage small cell lung cancer . J Clin Oncol . 1997;15:3030–3037
  5. Skarlos DV , Samantas E , Briassoulis E , et al.   Randomized comparison of early versus late hyperfractionated thoracic irradiation concurrently with chemotherapy in limited disease small-cell lung cancer (A randomized phase II study of the Hellenic Cooperative Oncology group (HeCOG)) . Ann Oncol . 2001;12:1231–1238
  6. Takada M , Fukuoka M , Kawahara M , et al.   Phase III study of concurrent versus sequential thoracic radiotherapy in combination with cisplatin and etoposide for limited-stage small-cell lung cancer (Results of the Japan Clinical Oncology Group study 9104) . J Clin Oncol . 2002;20:3054–3060
  7. Fried DB , Morris DE , Poole C , et al.   Systematic review evaluating the timing of thoracic radiation therapy in combined modality therapy for limited-stage small-cell lung cancer . J Clin Oncol . 2004;22:4785–4793
  8. Huncharek M , McGarry R . A meta-analysis of the timing of chest irradiation in the combined modality treatment of limited-stage small cell lung cancer . Oncologist . 2004;9:6665–6672
  9. Pijls-Johannesma MCG , de Ruysscher D , Lambin P , et al.   Early versus late chest radiotherapy for limited stage small cell lung cancer [Review] . Cochrane Database Syst Rev . 2005;1: CD004700
  10. Videtic GMM , Fung K , Tomiak AT , et al.   Using treatment interruptions to palliate the toxicity from concurrent chemoradiation for limited small cell lung cancer decreases survival and disease control . Lung Cancer . 2001;249–258
  11. Turrisi AT , Kim K , Blum R , et al.   Twice-daily compared with once-daily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposide . N Engl J Med . 1999;340:264–271

PII: S0360-3016(05)02958-5

doi: 10.1016/j.ijrobp.2005.10.034

International Journal of Radiation Oncology * Biology * Physics
Volume 64, Issue 4 , Pages 981-982 , 15 March 2006

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