International Journal of Radiation Oncology * Biology * Physics
Volume 65, Issue 5 , Pages 1338-1344 , 1 August 2006

A prospective study on radiation-induced changes in hearing function

  • Franziska Herrmann, M.D.

      Affiliations

    • Department of Oto-Rhino-Laryngology, University of Technology-Dresden, Dresden, Germany
    • ,
  • Wolfgang Dörr, D.V.M., Ph.D.

      Affiliations

    • Department of Radiotherapy and Radiation Oncology, University of Technology-Dresden, Dresden, Germany
    • Experimental Center, Medical Faculty Carl Gustav Carus, University of Technology-Dresden, Dresden, Germany
    • ,
  • Rainer Müller, M.D., Ph.D.

      Affiliations

    • Department of Oto-Rhino-Laryngology, University of Technology-Dresden, Dresden, Germany
    • ,
  • Thomas Herrmann, M.D., Ph.D.

      Affiliations

    • Department of Radiotherapy and Radiation Oncology, University of Technology-Dresden, Dresden, Germany
    • Corresponding Author InformationReprint requests to: Thomas Herrmann, M.D., Ph.D., Klinik und Poliklinik für Strahlentherapie und Radioonkologie, Medizinische Fakultät Carl Gustav Carus, Fetscherstrasse 74, D-01307 Dresden, Germany. Tel: (+49) 351-458-3373; Fax: (+49) 351-458-4347

Received 11 May 2005 ,Revised 28 March 2006 ,Accepted 28 March 2006.

References 

  1. Ewald CA . Die Wirkung des Radium auf das Labyrinth . Zentralbl Physiol . 1905;10:298–305
  2. Birkenhake S . Late sequelae affecting the ear . In:  Dunst J ,  Sauer R editor. Late sequelae in oncology . Berlin-Heidelberg-New York: Springer; 1995;p. 73–81
  3. Grau C , Overgaard J . Postirradiation sensorineural hearing loss (A common but ignored late radiation complication) . Int J Radiat Oncol Biol Phys . 1996;36:515–517
  4. Jereczek-Fossa BA , Zarowski A , Milani F , Orecchia R . Radiotherapy-induced ear toxicity . Cancer Treat Rev . 2003;29:417–430
  5. Plowman PN . Post-radiation sensorineural hearing loss . Int J Radiat Oncol Biol Phys . 2002;52:589–591
  6. Raaijmakers E , Engelen AM . Is sensorineural hearing loss a possible side effect of nasopharyngeal and parotid irradiation? A systematic review of the literature . Radiother Oncol . 2002;65:1–7
  7. Sataloff RT , Rosen DC . Effects of cranial irradiation on hearing acuity (A review of the literature) . Am J Otol . 1994;15:772–780
  8. Pan CC , Eisbruch A , Lee JS , et al.   Prospective study of inner ear radiation dose and hearing loss in head-and-neck cancer patients . Int J Radiat Oncol Biol Phys . 2005;61:1393–1402
  9. Kwong DLW , Wei WI , Sham JS , et al.   Sensorineural hearing loss in patients treated for nasopharyngeal carcinoma (A prospective study of the effect of radiation and cisplatin treatment) . Int J Radiat Oncol Biol Phys . 1996;36:281–289
  10. Joiner MC , Bentzen SM . Time-dose relationships (the linear-quadratic approach) . In:  Steel GG editors. Basic clinical radiobiology . London: Arnold; 2002;p. 120–133
  11. Thames HD , Withers HR , Peters LJ . Tissue repair capacity and repair kinetics deduced from multifractionated of continuous irradiation regimes with incomplete repair . Br J Cancer . 1984;49(Suppl. VI):263–269
  12. SAS Institute Inc. . (Cary, NC 27512–8000, U.S.A.), SAS/STAT User’s Guide, Version 6 . 4th Ed.. 1990;
  13. Balraj A , Raman R , Rangad F . Effects of radiation on hearing in patients with malignancies of head and neck . Singapore Med . 1992;33:481–483
  14. Grau C , Møller K , Overgaard M , et al.   Sensori-neural hearing loss in patients treated with irradiation for nasopharyngeal carcinoma . Int J Radiat Oncol Biol Phys . 1991;21:723–728
  15. Honore HB , Bentzen SM , Møller K , et al.   Sensori-neural hearing loss after radiotherapy for nasopharyngeal carcinoma (Individualized risk estimation) . Radiother Oncol . 2002;65:9–16
  16. Leach W . Irradiation of the ear . J Laryngol Otol . 1965;79:870–880
  17. Oh YT , Kim CH , Choi JH , et al.   Sensory neural hearing loss after concurrent cisplatin and radiation therapy for nasopharyngeal carcinoma . Radiother Oncol . 2004;72:79–82
  18. Ho WK , Wie WI , Kwong DL , et al.   Long-term sensorineural hearing deficit following radiotherapy in patients suffering from nasopharyngeal carcinoma (A prospective study) . Head Neck . 1999;21:547–553
  19. Von Specht H , Völker W , Reinhardt U , et al.   Der diagnostische Wert neuropsychiatrischer, audiologischer und elektrophysiologischer Untersuchungen an alkoholabhängigen Patienten . HNO . 1982;30:381–390
  20. Anteunis LJ , Wanders SL , Hendriks JJ , et al.   A prospective longitudinal study on radiation-induced hearing loss . Am J Surg . 1994;168:408–411
  21. Varghese G , Sahota JS , Hazarika P , et al.   Hearing anomalies following radiation therapy for head and neck cancers . Indian J Exp Biol . 1996;34:878–879
  22. Wang LF , Kuo WR , Ho KY , et al.   A long-term study on hearing status in patients with nasopharyngeal carcinoma after radiotherapy . Otol Neurotol . 2004;25:168–173
  23. Kashiwamura M , Fukuda S , Chida E , et al.   Sensorineural hearing loss induced by radiation as a late effect (five cases followed by audiogram) . Auris Nasus Larynx . 2001;28(Suppl):S111–S115
  24. Chen WC , Liao CT , Tsai HC , et al.   Radiation-induced hearing impairment in patients treated for malignant parotid tumor . Ann Otol Rhinol Laryngol . 1999;108:1159–1164
  25. Schot LJ , Hilgers FJ , Keus RB , et al.   Late effects of radiotherapy on hearing . Eur Arch Otorhinolaryngol . 1992;249:305–308
  26. Johannesen TB , Rasmussen K , Winther FO , et al.   Late radiation effects on hearing, vestibular function, and taste in brain tumor patients . Int J Radiat Oncol Biol Phys . 2002;53:86–90
  27. Merchant TE , Gould CJ , Xiong X , et al.   Early neuro-otologic effects of three-dimensional irradiation in children with primary brain tumors . Int J Radiat Oncol Biol Phys . 2004;58:1194–1207
  28. Linskey ME , Johnstone PAS . Radiation tolerance of normal temporal bone structures (Implications for gamma knife stereotactic radiosurgery) . Int J Radiat Oncol Biol Phys . 2003;57:196–200
  29. Wang CC . Radiation therapy for head and neck neoplasm (Indications, techniques, and results) . Chicago: Year Book Medical Publishers; 1990;
  30. Hoistad DL , Ondrey FG , Mutlu C , et al.   Histopathology of human temporal bone after cis-platinum, radiation, or both . Otolaryngol Head Neck Surg . 1998;118:825–832

PII: S0360-3016(06)00530-X

doi: 10.1016/j.ijrobp.2006.03.032

International Journal of Radiation Oncology * Biology * Physics
Volume 65, Issue 5 , Pages 1338-1344 , 1 August 2006

Article Tools

* Image Usage & Resolution