International Journal of Radiation Oncology * Biology * Physics
Volume 66, Issue 5 , Pages 1347-1355 , 1 December 2006

Cyclooxygenase-2 impairs treatment effects of radiotherapy for cervical cancer by inhibition of radiation-induced apoptosis

  • Hitoshi Ishikawa, M.D., Ph.D.

      Affiliations

    • Research Center for Charged Particle Therapy, National Institute of Radiological Sciences (NIRS), Chiba, Japan
    • Department of Radiation Oncology, Gunma University Graduate School of Medicine, Gunma, Japan
    • Corresponding Author InformationReprint requests to: Hitoshi Ishikawa, M.D., Ph.D., Department of Radiation Oncology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511 Japan. Tel: (+81) 27-220-8383; Fax: (+81) 27-220-8397.
    • ,
  • Tatsuya Ohno, M.D., Ph.D.

      Affiliations

    • Research Center for Charged Particle Therapy, National Institute of Radiological Sciences (NIRS), Chiba, Japan
    • ,
  • Shingo Kato, M.D., Ph.D.

      Affiliations

    • Research Center for Charged Particle Therapy, National Institute of Radiological Sciences (NIRS), Chiba, Japan
    • ,
  • Masaru Wakatsuki, M.D.

      Affiliations

    • Department of Radiation Oncology, Gunma University Graduate School of Medicine, Gunma, Japan
    • ,
  • Mayumi Iwakawa, M.D., Ph.D.

      Affiliations

    • Research Center for Charged Particle Therapy, National Institute of Radiological Sciences (NIRS), Chiba, Japan
    • ,
  • Toshie Ohta, M.S.

      Affiliations

    • Research Center for Charged Particle Therapy, National Institute of Radiological Sciences (NIRS), Chiba, Japan
    • ,
  • Takashi Imai, M.D., Ph.D.

      Affiliations

    • Research Center for Charged Particle Therapy, National Institute of Radiological Sciences (NIRS), Chiba, Japan
    • ,
  • Norio Mitsuhashi, M.D., Ph.D.

      Affiliations

    • Department of Radiology, Tokyo Women’s Medical University, Tokyo, Japan
    • ,
  • Shin-ei Noda, M.D.

      Affiliations

    • Department of Radiation Oncology, Gunma University Graduate School of Medicine, Gunma, Japan
    • ,
  • Takashi Nakano, M.D., Ph.D.

      Affiliations

    • Department of Radiation Oncology, Gunma University Graduate School of Medicine, Gunma, Japan
    • ,
  • Hirohiko Tsujii, M.D., Ph.D.

      Affiliations

    • Research Center for Charged Particle Therapy, National Institute of Radiological Sciences (NIRS), Chiba, Japan

Received 12 May 2006 ,Revised 29 June 2006 ,Accepted 2 July 2006.

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 This work was supported by Grants-in-Aid for Scientific Research on Priority Area (17016073) and Scientific Research (17790884) from the Ministry of Education, Culture, Sports, Science and Technology of Japan.

PII: S0360-3016(06)01179-5

doi: 10.1016/j.ijrobp.2006.07.007

International Journal of Radiation Oncology * Biology * Physics
Volume 66, Issue 5 , Pages 1347-1355 , 1 December 2006

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