International Journal of Radiation Oncology * Biology * Physics
Volume 67, Issue 1 , Pages 6-9, 1 January 2007

Administration of the peroxisomal proliferator-activated receptor γ agonist pioglitazone during fractionated brain irradiation prevents radiation-induced cognitive impairment

  • Weiling Zhao, Ph.D.

      Affiliations

    • Department of Radiation Oncology, Brain Tumor Center of Excellence, Wake Forest University School of Medicine, Winston-Salem, NC
    • ,
  • Valerie Payne, B.S.

      Affiliations

    • Department of Radiation Oncology, Brain Tumor Center of Excellence, Wake Forest University School of Medicine, Winston-Salem, NC
    • ,
  • Ellen Tommasi, B.S.

      Affiliations

    • Hypertension and Vascular Disease Center, Wake Forest University School of Medicine, Winston-Salem, NC
    • ,
  • Debra I. Diz, Ph.D.

      Affiliations

    • Hypertension and Vascular Disease Center, Wake Forest University School of Medicine, Winston-Salem, NC
    • ,
  • Fang-Chi Hsu, Ph.D.

      Affiliations

    • Department of Biostatistical Sciences, Wake Forest University School of Medicine, Winston-Salem, NC
    • ,
  • Mike E. Robbins, Ph.D.

      Affiliations

    • Department of Radiation Oncology, Brain Tumor Center of Excellence, Wake Forest University School of Medicine, Winston-Salem, NC
    • Corresponding Author InformationReprint requests to: Mike E. Robbins, M.D., Room 412C NRC, Department of Radiation Oncology, Wake Forest University School of Medicine, Medical Center Blvd, Winston-Salem, NC 27157. Tel: (336) 713-7635; Fax: (336) 713-7639

Received 15 September 2006; received in revised form 21 September 2006; accepted 22 September 2006.

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 Supported by National Institutes of Health grants CA112593 (MER) and HL51952 (DIZ).Conflict of interest: none.

PII: S0360-3016(06)03128-2

doi:10.1016/j.ijrobp.2006.09.036

International Journal of Radiation Oncology * Biology * Physics
Volume 67, Issue 1 , Pages 6-9, 1 January 2007

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