« Previous
Next »
International Journal of Radiation Oncology * Biology * Physics
Volume 67, Issue 5
, Pages 1323-1331
, 1 April 2007
A Phase II Multi-institutional Trial of Chemoradiation Using Weekly Docetaxel and Erythropoietin for High-Risk Postoperative Head and Neck Cancer Patients
References
- Postoperative irradiation with or without concomitant chemotherapy for locally advanced head and neck cancer. N Engl J Med. 2004;350:1945–1952
- Postoperative concurrent radiotherapy and chemotherapy for high-risk squamous-cell carcinoma of the head and neck. N Engl J Med. 2004;350:1937–1944
- . Taxol stabilizes microtubules in mouse fibroblast cells. Proc Natl Acad Sci U S A. 1980;77:1561–1565
- Phase I study of docetaxel administered as a 1-hour intravenous infusion on a weekly basis. J Clin Oncol. 1994;12:1458–1467
- Phase I clinical trial of Taxotere administered as either a 2-hour or 6-hour intravenous infusion. J Clin Oncol. 1993;11:950–958
- Investigation of taxol as a potential radiation sensitizer. Cancer. 1993;71:3774–3778
- Taxol: a novel radiation sensitizer. Int J Radiat Oncol Biol Phys. 1992;22:613–617
- . Interaction of ionizing radiation with paclitaxel (Taxol) and docetaxel (Taxotere) in HeLa and SQ20B cells. Cancer Res. 1996;56:1842–1850
- . Differing responses to radiation of murine bone marrow stem cells in relation to the cell cycle. Cancer Res. 1971;31:1613–1615
- Low concentrations of paclitaxel induce cell type-dependent p53, p21 and G1/G2 arrest instead of mitotic arrest: Molecular determinants of paclitaxel-induced cytotoxicity. Oncogene. 2001;20:3806–3813
- Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death. Cancer Res. 1996;56:816–825
- Comparative pharmacokinetics of weekly and every-three-weeks docetaxel. Clin Cancer Res. 2004;10:1976–1983
- . Advanced head and neck cancer and clinical experience of an effective new agent: Docetaxel. Anticancer Res. 1998;18:4751–4756
- Docetaxel: An active drug for squamous cell carcinoma of the head and neck. J Clin Oncol. 1996;14:1672–1678
- Docetaxel and cisplatin: An active regimen in patients with locally advanced, recurrent or metastatic squamous cell carcinoma of the head and neck (Results of a phase II study of the EORTC Early Clinical Studies Group). Ann Oncol. 1999;10:119–122
- Docetaxel, cisplatin, and 5-fluorouracil-based induction chemotherapy in patients with locally advanced squamous cell carcinoma of the head and neck—The Dana Farber Cancer Institute experience. Cancer. 2003;97:412–418
- . Docetaxel induction therapy in locally advanced squamous cell carcinoma of the head and neck. British J Cancer. 2003;88:11–17
- . Docetaxel with concurrent radiotherapy in head and neck cancer. Semin Oncol. 2003;30:89–93
- . Standard cisplatin/infusional 5-fluorouracil (PF) vs docetaxel (T) plus PF (TPF) as neoadjuvant chemotherapy for nonresectable locally advanced squamous cell carcinoma of the head and neck (LA-SCCHN): A phase III trial of the EORTC Head and Neck Cancer Group (EORTC #24971). J Clin Oncol. 2004;22(Suppl):490s–490s
- . Paradigm shift in the treatment of head and neck cancer: The role of neoadjuvant chemotherapy. Oncologist. 2005;10(Suppl 3):11–19
- Phase I trial of weekly docetaxel and concurrent radiotherapy for head and neck cancer in elderly patients or patients with complications. Jpn J Clin Oncol. 2005;35:173–176
- A multicentre, randomised phase II study of weekly or 3-weekly docetaxel in patients with metastatic breast cancer. Ann Oncol. 2004;15:1358–1365
- Phase II randomised trial comparing docetaxel given every 3 weeks with weekly schedule as second-line therapy in patients with advanced non-small-cell lung cancer (NSCLC). Ann Oncol. 2005;16:90–96
- A randomised clinical trial of two docetaxel regimens (weekly vs 3 week) in the second-line treatment of non-small-cell lung cancer (The DISTAL 01 study). Br J Cancer. 2004;91:1996–2004
- . Erythropoietin increases hemoglobin in cancer-patients during radiation-therapy. Int J Radiat Oncol Biol Physics. 1993;27:1147–1152
- Oxygenation of head and neck cancer: Changes during radiotherapy and impact on treatment outcome. Radiother Oncol. 1999;53:113–117
- Pretreatment anemia is correlated with the reduced effectiveness of radiation and concurrent chemotherapy in advanced head and neck cancer. Int J Radiat Oncol Biol Physics. 2005;61:1087–1095
- . 6th interim analysis of a prospective, randomized, open and controlled AGO- and NOGGO-intergroup study sequential adjuvant chemo-radiotherapy with vs. without epoetin alfa for patients with high risk cervical cancer. Proc Am Soc Clin Oncol. 2003;22:447
- . Once-weekly dosing of epoetin-alpha increases hemoglobin and improves quality of life in anemic cancer patients receiving radiation therapy either concomitantly or sequentially with chemotherapy. Cancer. 2003;98:1072–1079
- Epoetin-alpha during radiotherapy for stage III esophageal carcinoma. Cancer. 2005;103:2274–2279
- Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer. N Engl J Med. 1998;338:1798–1804
- Continuous hyperfractionated accelerated radiotherapy with/without mitomycin C in head and neck cancer. Int J Radiat Oncol Biol Phys. 1998;42:803–806
- . Continuous hyperfractionated accelerated radiotherapy with/without mitomycin C in head and neck cancers. Radiother Oncol. 2000;57:119–124
- Simultaneous radiochemotherapy versus radiotherapy alone in advanced head and neck cancer: A randomized multicenter study. J Clin Oncol. 1998;16:1318–1324
- Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma. J Natl Cancer Inst. 1999;91:2081–2086
- Radiotherapy with concomitant weekly docetaxel for Stages III/IV oropharynx carcinoma (Results of the 98–02 GORTEC Phase II trial). Int J Radiat Oncol Biol Phys. 2004;58:161–166
- . Adjuvant and adjunctive chemotherapy in the management of squamous cell carcinoma of the head and neck region (A meta-analysis of prospective and randomized trials). J Clin Oncol. 1996;14:838–847
- . An overview of randomised controlled trials of adjuvant chemotherapy in head and neck cancer. Br J Cancer. 1995;71:83–91
- . Meta-analyses in head and neck squamous cell carcinoma (What is the role of chemotherapy?). Hematol Oncol Clin North Am. 1999;13:769–775vii
- Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: Three meta-analyses of updated individual data (Meta-Analysis of Chemotherapy on Head and Neck Cancer). Lancet. 2000;355:949–955
- . [Individual patient data meta-analyses in head and neck carcinoma: what have we learnt?]. Cancer Radiother. 2005;9:31–36[In French]
- . Chemoradiation after surgery for high-risk head and neck cancer patients: How strong is the evidence?. Oncologist. 2005;10:215–224
- Phase I study of weekly outpatient paclitaxel and concurrent cranial irradiation in adults with astrocytomas. J Clin Oncol. 1996;14:600–609
- Phase I study of concomitant chemoradiotherapy with paclitaxel, fluorouracil, and hydroxyurea with granulocyte colony-stimulating factor support for patients with poor-prognosis cancer of the head and neck. J Clin Oncol. 1998;16:735–744
- Combined modality therapy in non–small cell lung and esophageal cancer: A phase I dose-escalation study of docetaxel with concurrent radiotherapy. Semin Oncol. 1998;25:28–32
- Concurrent paclitaxel and radiation therapy for breast cancer. Semin Radiat Oncol. 1999;9:34–42
- Phase II trial of weekly paclitaxel and concurrent radiation therapy for locally advanced non–small cell lung cancer. Clin Cancer Res. 1998;4:1931–1936
- Weekly docetaxel and concomitant boost radiotherapy for non–small cell lung cancer (A phase I/II dose escalation trial). Eur J Cancer. 1998;34:838–844
- Phase I study of docetaxel with concomitant thoracic radiation therapy. J Clin Oncol. 1998;16:159–164
- Induction chemotherapy with docetaxel, cisplatin, fluorouracil, and leucovorin for squamous cell carcinoma of the head and neck: A Phase I/II trial. J Clin Oncol. 1998;16:1331–1339
- Phase II trial of docetaxel, cisplatin, fluorouracil, and leucovorin as induction for squamous cell carcinoma of the head and neck. J Clin Oncol. 1999;17:3503–3511
- Multicenter Phase I–II trial of docetaxel, cisplatin, and fluorouracil induction chemotherapy for patients with locally advanced squamous cell cancer of the head and neck. J Clin Oncol. 2001;19:1096–1104
- Phase I/II trial of outpatient docetaxel, cisplatin, 5-fluorouracil, leucovorin (opTPFL) as induction for squamous cell carcinoma of the head and neck (SCCHN). Am J Clin Oncol. 2002;25:153–159
- Phase II study of induction chemotherapy with paclitaxel, ifosfamide, and carboplatin (TIC) for patients with locally advanced squamous cell carcinoma of the head and neck. Cancer. 2002;95:322–330
- Induction paclitaxel and carboplatin for patients with head and neck carcinoma (Analysis of 62 patients treated between 1994 and 1999). Cancer. 2001;91:940–948
- Docetaxel, cisplatin, 5-fluorouracil (TPF)-based induction chemotherapy for head and neck cancer and the case for sequential, combined-modality treatment. Oncologist. 2003;8:35–44
- Phase III study comparing cisplatin plus fluorouracil to paclitaxel, cisplatin, and fluorouracil induction chemotherapy followed by chemoradiotherapy in locally advanced head and neck cancer. J Clin Oncol. 2005;23:8636–8645
- Phase I trial of concomitant hyperfractionated radiotherapy with docetaxel and cisplatin for locally advanced head and neck cancer. Cancer J. 2006;12:63–68
- . A Phase I/II trial of concurrent docetaxel and radiation after induction chemotherapy in patients with poor prognosis squamous cell carcinoma of the head and neck. Cancer. 2002;95:1472–1481
- Phase I/II trial of weekly docetaxel and concomitant radiotherapy for squamous cell carcinoma of the head and neck. Int J Clin Oncol. 2004;9:107–112
- . Maximized combined modality treatment of an unselected population of oral and oropharyngeal cancer patients (Final results of a pilot study compared with a treatment-dependent prognosis index). J Craniomaxillofac Surg. 2006;34:74–84
- . Combined modality treatment of oral and oropharyngeal cancer including neoadjuvant intraarterial cisplatin and radical surgery followed by concurrent radiation and chemotherapy with weekly docetaxel—three year results of a pilot study. J Craniomaxillofac Surg. 2002;30:112–120
- Phase I study of weekly docetaxel infusion and concurrent radiation therapy for head and neck cancer. Jpn J Clin Oncol. 2003;33:297–301
- Multimodality treatment including postoperative radiation and concurrent chemotherapy with weekly docetaxel is feasible and effective in patients with oral and oropharyngeal cancer. Strahlenther Onkol. 2005;181:26–34
- Concurrent weekly docetaxel and concomitant boost radiation therapy in the treatment of locally advanced squamous cell cancer of the head and neck. Int J Radiat Oncol Biol Phys. 2006;65:1036–1044
- . The role of induction chemotherapy in the curative treatment of squamous cell cancer of the head and neck. Semin Oncol. 2000;27:13–24
- Sequential chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil in patients with locally advanced head and neck cancer. Am J Clin Oncol. 2001;24:227–231
- Weekly docetaxel in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck. Cancer. 2006;106:106–111
- Paclitaxel sensitizes multidrug resistant cells to radiation. Anticancer Drugs. 1996;7:182–188
- Pharmacokinetic monitoring and dose modification of etanidazole in the RTOG 85–27 phase III head and neck trial. Int J Radiat Oncol Biol Phys. 1997;39:855–858
- Anemia is associated with decreased survival and increased locoregional failure in patients with locally advanced head and neck carcinoma: A secondary analysis of RTOG 85–27. Int J Radiat Oncol Biol Physics. 1998;42:1069–1075
- Pretreatment hemoglobin level influences local-control and survival of T1-T2 squamous-cell carcinomas of the glottic larynx. J Clinical Oncol. 1995;13:2077–2083
- Primary radiotherapy of larynx and pharynx carcinoma—an analysis of some factors influencing local-control and survival. Int J Radiat Oncol Biol Physics. 1986;12:515–521
- Standard of care for cancer-related anemia: Improving hemoglobin levels and quality of life. Oncology. 2005;68(Suppl 1):22–32
- rHuEPO and treatment outcomes: The clinical experience. Oncologist. 2004;9(Suppl 5):55–69
- Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: Randomised, double-blind, placebo-controlled trial. Lancet. 2003;362:1255–1260
- . Breast cancer trial with erythropoietin terminated unexpectedly. Lancet Oncol. 2003;4:459–460
- Effects of epoetin alfa on hematologic parameters and quality of life in cancer patients receiving nonplatinum chemotherapy: Results of a randomized, double-blind, placebo-controlled trial. J Clin Oncol. 2001;19:2865–2874
- . Anemia, tumor hypoxemia, and the cancer patient. Int J Radiat Oncol Biol Phys. 2005;63:25–36
- Erythropoietin in cancer treatment: considerations about Henke’s article. Clin Transl Oncol. 2005;7:332–335
- . Erythropoietin to treat anaemia in patients with head and neck cancer. Lancet. 2004;363:78–79author reply 81–72
- . Erythropoietin to treat anaemia in patients with head and neck cancer. Lancet. 2004;363:80;author reply 81–82
- Definitive radiotherapy +/− erythropoietin for squamous cell carcinoma of the head and neck: Preliminary report of RTOG 99–03. Int J Radiat Oncol Biol Physics. 2004;60:S132–S132
This research was supported by Sanofi Aventis.Conflict of interest: none.
PII: S0360-3016(06)03504-8
doi: 10.1016/j.ijrobp.2006.11.033
© 2007 Elsevier Inc. All rights reserved.
« Previous
Next »
International Journal of Radiation Oncology * Biology * Physics
Volume 67, Issue 5
, Pages 1323-1331
, 1 April 2007
