International Journal of Radiation Oncology * Biology * Physics
Volume 69, Issue 3 , Pages 777-785 , 1 November 2007

Implantation and Stability of Metallic Fiducials Within Pulmonary Lesions

  • Patrick A. Kupelian, M.D.

      Affiliations

    • Department of Radiation Oncology, M. D. Anderson Cancer Center Orlando, Orlando, FL
    • Corresponding Author InformationReprint requests to: Patrick A. Kupelian, M.D., Department of Radiation Oncology, M. D. Anderson Cancer Center Orlando, 1400 South Orange Ave., Orlando, FL 32806. Tel: (321) 841-8666; Fax: (407) 649-6895
    • ,
  • Alan Forbes, M.D., Ph.D.

      Affiliations

    • Department of Radiation Oncology, M. D. Anderson Cancer Center Orlando, Orlando, FL
    • ,
  • Twyla R. Willoughby, M.S.

      Affiliations

    • Department of Radiation Oncology, M. D. Anderson Cancer Center Orlando, Orlando, FL
    • ,
  • Karen Wallace, M.D.

      Affiliations

    • Florida State University College of Medicine, Tallahassee, FL
    • ,
  • Rafael R. Mañon, M.D.

      Affiliations

    • Department of Radiation Oncology, M. D. Anderson Cancer Center Orlando, Orlando, FL
    • ,
  • Sanford L. Meeks, Ph.D.

      Affiliations

    • Department of Radiation Oncology, M. D. Anderson Cancer Center Orlando, Orlando, FL
    • ,
  • Luis Herrera, M.D.

      Affiliations

    • Department of Thoracic Surgery, M. D. Anderson Cancer Center Orlando, Orlando, FL
    • ,
  • Alan Johnston, M.D.

      Affiliations

    • Department of Thoracic Surgery, M. D. Anderson Cancer Center Orlando, Orlando, FL
    • ,
  • Juan J. Herran, M.D.

      Affiliations

    • Thoracic Care Center, M. D. Anderson Cancer Center Orlando, Orlando, FL

Received 5 February 2007 ,Revised 22 March 2007 ,Accepted 22 March 2007.

References 

  1. Chen QS, Weinhous MS, Deibel FC, et al. Fluoroscopic study of tumor motion due to breathing: Facilitating precise radiation therapy for lung cancer patients. Med Phys. 2001;28:1850–1856
  2. Harada T, Shirato H, Ogura S, et al. Real-time tumor-tracking radiation therapy for lung carcinoma by the aid of insertion of a gold marker using bronchofiberscopy. Cancer. 2002;95:1720–1727
  3. Korreman S, Mostafavi H, Le QT, et al. Comparison of respiratory surrogates for gated lung radiotherapy without internal fiducials. Acta Oncol. 2006;45:935–942
  4. Onimaru R, Shirato H, Fujino M, et al. The effect of tumor location and respiratory function on tumor movement estimated by real-time tracking radiotherapy (RTRT) system. Int J Radiat Oncol Biol Phys. 2005;63:164–169
  5. Shimizu S, Shirato H, Ogura S, et al. Detection of lung tumor movement in real-time tumor-tracking radiotherapy. Int J Radiat Oncol Biol Phys. 2001;51:304–310
  6. Shirato H, Seppenwoolde Y, Kitamura K, et al. Intrafractional tumor motion: Lung and liver. Semin Radiat Oncol. 2004;14:10–18
  7. Starkschall G, Forster KM, Kitamura K, et al. Correlation of gross tumor volume excursion with potential benefits of respiratory gating. Int J Radiat Oncol Biol Phys. 2004;60:1291–1297
  8. Willoughby TR, Forbes AR, Buchholz D, et al. Evaluation of an infrared camera and X-ray system using implanted fiducials in patients with lung tumors for gated radiation therapy. Int J Radiat Oncol Biol Phys. 2006;66:568–575
  9. Keall P, Vedam S, George R, et al. The clinical implementation of respiratory-gated intensity-modulated radiotherapy. Med Dosim. 2006;31:152–162
  10. Jiang SB. Technical aspects of image-guided respiration-gated radiation therapy. Med Dosim. 2006;31:141–151
  11. Sharp GC, Jiang SB, Shimizu S, et al. Prediction of respiratory tumour motion for real-time image-guided radiotherapy. Phys Med Biol. 2004;49:425–440
  12. Stock M, Kontrisova K, Dieckmann K, et al. Development and application of a real-time monitoring and feedback system for deep inspiration breath hold based on external marker tracking. Med Phys. 2006;33:2868–2877
  13. Mageras GS, Yorke E. Deep inspiration breath hold and respiratory gating strategies for reducing organ motion in radiation treatment. Semin Radiat Oncol. 2004;14:65–75
  14. Barnes EA, Murray BR, Robinson DM, et al. Dosimetric evaluation of lung tumor immobilization using breath hold at deep inspiration. Int J Radiat Oncol Biol Phys. 2001;50:1091–1098
  15. Nuyttens JJ, Prevost JB, Praag J, et al. Lung tumor tracking during stereotactic radiotherapy treatment with the CyberKnife: Marker placement and early results. Acta Oncol. 2006;45:961–965
  16. Whyte RI, Crownover R, Murphy MJ, et al. Stereotactic radiosurgery for lung tumors: Preliminary report of a phase I trial. Ann Thorac Surg. 2003;75:1097–1101
  17. Hoisak JD, Sixel KE, Tirona R, et al. Prediction of lung tumour position based on spirometry and on abdominal displacement: Accuracy and reproducibility. Radiother Oncol. 2006;78:339–346
  18. Chi PC, Balter P, Luo D, et al. Relation of external surface to internal tumor motion studied with cine CT. Med Phys. 2006;33:3116–3123
  19. Isaksson M, Jalden J, Murphy MJ. On using an adaptive neural network to predict lung tumor motion during respiration for radiotherapy applications. Med Phys. 2005;32:3801–3809
  20. Berbeco RI, Nishioka S, Shirato H, et al. Residual motion of lung tumours in gated radiotherapy with external respiratory surrogates. Phys Med Biol. 2005;50:3655–3667
  21. Shirato H, Suzuki K, Sharp GC, et al. Speed and amplitude of lung tumor motion precisely detected in four-dimensional setup and in real-time tumor-tracking radiotherapy. Int J Radiat Oncol Biol Phys. 2006;64:1229–1236
  22. Covey AM, Gandhi R, Brody LA, et al. Factors associated with pneumothorax and pneumothorax requiring treatment after percutaneous lung biopsy in 443 consecutive patients. J Vasc Interv Radiol. 2004;15:479–483
  23. Cox JE, Chiles C, McManus CM, et al. Transthoracic needle aspiration biopsy: Variables that affect risk of pneumothorax. Radiology. 1999;212:165–168
  24. Fish GD, Stanley JH, Miller KS, et al. Postbiopsy pneumothorax: Estimating the risk by chest radiography and pulmonary function tests. AJR Am J Roentgenol. 1988;150:71–74
  25. Gildea TR, Mazzone PJ, Karnak D, et al. Electromagnetic navigation diagnostic bronchoscopy: A prospective study. Am J Respir Crit Care Med. 2006;174:982–989
  26. Schwarz Y, Greif J, Becker HD, et al. Real-time electromagnetic navigation bronchoscopy to peripheral lung lesions using overlaid CT images: The first human study. Chest. 2006;129:988–994
  27. Schwarz Y, Mehta AC, Ernst A, et al. Electromagnetic navigation during flexible bronchoscopy. Respiration. 2003;70:516–522
  28. Kupelian PA, Ramsey C, Meeks SL, et al. Serial megavoltage CT imaging during external beam radiotherapy for non-small-cell lung cancer: Observations on tumor regression during treatment. Int J Radiat Oncol Biol Phys. 2005;63:1024–1028
  29. Jin JY, Ajlouni M, Chen Q, et al. A technique of using gated-CT images to determine internal target volume (ITV) for fractionated stereotactic lung radiotherapy. Radiother Oncol. 2006;78:177–184
  30. Chang J, Sillanpaa J, Ling CC, et al. Integrating respiratory gating into a megavoltage cone-beam CT system. Med Phys. 2006;33:2354–2361
  31. Plathow C, Zimmermann H, Fink C, et al. Influence of different breathing maneuvers on internal and external organ motion: Use of fiducial markers in dynamic MRI. Int J Radiat Oncol Biol Phys. 2005;62:238–245
  32. Koch N, Liu HH, Starkschall G, et al. Evaluation of internal lung motion for respiratory-gated radiotherapy using MRI: Part I—Correlating internal lung motion with skin fiducial motion. Int J Radiat Oncol Biol Phys. 2004;60:1459–1472
  33. Keall PJ, Todor AD, Vedam SS, et al. On the use of EPID-based implanted marker tracking for 4D radiotherapy. Med Phys. 2004;31:3492–3499
  34. Vedam SS, Kini VR, Keall PJ, et al. Quantifying the predictability of diaphragm motion during respiration with a noninvasive external marker. Med Phys. 2003;30:505–513
  35. Shirato H, Harada T, Harabayashi T, et al. Feasibility of insertion/implantation of 2.0-mm-diameter gold internal fiducial markers for precise setup and real-time tumor tracking in radiotherapy. Int J Radiat Oncol Biol Phys. 2003;56:240–247
  36. Seppenwoolde Y, Shirato H, Kitamura K, et al. Precise and real-time measurement of 3D tumor motion in lung due to breathing and heartbeat, measured during radiotherapy. Int J Radiat Oncol Biol Phys. 2002;53:822–834
  37. Ford EC, Mageras GS, Yorke E, et al. Evaluation of respiratory movement during gated radiotherapy using film and electronic portal imaging. Int J Radiat Oncol Biol Phys. 2002;52:522–531
  38. Mageras GS, Yorke E, Rosenzweig K, et al. Fluoroscopic evaluation of diaphragmatic motion reduction with a respiratory gated radiotherapy system. J Appl Clin Med Phys. 2001;2:191–200
  39. Shirato H, Shimizu S, Kunieda T, et al. Physical aspects of a real-time tumor-tracking system for gated radiotherapy. Int J Radiat Oncol Biol Phys. 2000;48:1187–1195
  40. Cui Y, Dy JG, Sharp GC, et al. Robust fluoroscopic respiratory gating for lung cancer radiotherapy without implanted fiducial markers. Phys Med Biol. 2007;52:741–755
  41. Imura M, Yamazaki K, Shirato H, et al. Insertion and fixation of fiducial markers for setup and tracking of lung tumors in radiotherapy. Int J Radiat Oncol Biol Phys. 2005;63:1442–1447
  42. Kitamura K, Shirato H, Shimizu S, et al. Registration accuracy and possible migration of internal fiducial gold marker implanted in prostate and liver treated with real-time tumor-tracking radiation therapy (RTRT). Radiother Oncol. 2002;62:275–281
  43. Kupelian PA, Willoughby TR, Meeks SL, et al. Intraprostatic fiducials for localization of the prostate gland: Monitoring intermarker distances during radiation therapy to test for marker stability. Int J Radiat Oncol Biol Phys. 2005;62:1291–1296
  44. Siker ML, Tome WA, Mehta MP. Tumor volume changes on serial imaging with megavoltage CT for non-small-cell lung cancer during intensity-modulated radiotherapy: How reliable, consistent, and meaningful is the effect?. Int J Radiat Oncol Biol Phys. 2006;66:135–141

 Conflict of interest: none.

PII: S0360-3016(07)00554-8

doi: 10.1016/j.ijrobp.2007.03.040

International Journal of Radiation Oncology * Biology * Physics
Volume 69, Issue 3 , Pages 777-785 , 1 November 2007

Article Tools

* Image Usage & Resolution