International Journal of Radiation Oncology * Biology * Physics
Volume 69, Issue 4 , Pages 1193-1198, 15 November 2007

Field-In-Field Technique With Intrafractionally Modulated Junction Shifts for Craniospinal Irradiation

  • Sue S. Yom, M.D., Ph.D.

      Affiliations

    • Division of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX
  • ,
  • Erik K. Frija, C.M.D.

      Affiliations

    • Division of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX
  • ,
  • Anita Mahajan, M.D.

      Affiliations

    • Division of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX
  • ,
  • Eric Chang, M.D.

      Affiliations

    • Division of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX
  • ,
  • Kelli Klein, C.M.D.

      Affiliations

    • Division of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX
  • ,
  • Almon Shiu, Ph.D.

      Affiliations

    • Department of Radiation Physics, The University of Texas M. D. Anderson Cancer Center, Houston, TX
  • ,
  • Jared Ohrt, M.S.

      Affiliations

    • Department of Radiation Physics, The University of Texas M. D. Anderson Cancer Center, Houston, TX
  • ,
  • Shiao Woo, M.D.

      Affiliations

    • Division of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX
    • Corresponding Author InformationReprint requests to: Shiao Woo, M.D., Division of Radiation Oncology, Box 97, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030. Tel: (713) 563-2324; Fax: (713) 563-1521

Received 3 March 2007; accepted 16 April 2007.

Purpose

To plan craniospinal irradiation with “field-in-field” (FIF) homogenization in combination with daily, intrafractional modulation of the field junctions, to minimize the possibility of spinal cord overdose.

Methods and Materials

Lateral cranial fields and posterior spinal fields were planned using a forward-planned, step-and-shoot FIF technique. Field junctions were automatically modulated and custom-weighted for maximal homogeneity within each treatment fraction. Dose–volume histogram analyses and film dosimetry were used to assess results.

Results

Plan inhomogeneity improved with FIF. Planning with daily modulated junction shifts provided consistent dose delivery during each fraction of treatment across the junctions. Modulation minimized the impact of a 5-mm setup error at the junction. Film dosimetry confirmed that no point in the junction exceeded the anticipated dose.

Conclusions

Field-in-field planning and modulated junction shifts improve the homogeneity and consistency of daily dose delivery, simplify treatment, and reduce the impact of setup errors.

Craniospinal irradiation planning, Junction shift, Field-in-field technique

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 Presented in part at the 88th Annual Meeting of the American Radium Society, May 6–10, 2006, Maui, HI.

 Conflict of interest: none.

PII: S0360-3016(07)00701-8

doi:10.1016/j.ijrobp.2007.04.062

International Journal of Radiation Oncology * Biology * Physics
Volume 69, Issue 4 , Pages 1193-1198, 15 November 2007