International Journal of Radiation Oncology * Biology * Physics
Volume 69, Issue 4 , Pages 1222-1230 , 15 November 2007

Enhanced Response of Human Head and Neck Cancer Xenograft Tumors to Cisplatin Combined With 2-Deoxy-d-Glucose Correlates With Increased 18F-FDG Uptake as Determined by PET Imaging

  • Andrean L. Simons, Ph.D.

      Affiliations

    • Department of Radiation Oncology, The Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA
  • ,
  • Melissa A. Fath, R.Ph., Ph.D.

      Affiliations

    • Department of Radiation Oncology, The Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA
  • ,
  • David M. Mattson, M.D.

      Affiliations

    • Department of Radiation Oncology, The Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA
  • ,
  • Brian J. Smith, Ph.D.

      Affiliations

    • Department of Biostatistics, The Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA
  • ,
  • Susan A. Walsh, M.A.

      Affiliations

    • Department of Radiation Oncology, The Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA
  • ,
  • Michael M. Graham, M.D., Ph.D.

      Affiliations

    • Department of Radiology, The Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA
  • ,
  • Richard D. Hichwa, Ph.D.

      Affiliations

    • Department of Radiology, The Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA
  • ,
  • John M. Buatti, M.D.

      Affiliations

    • Department of Radiation Oncology, The Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA
  • ,
  • Ken Dornfeld, M.D., Ph.D.

      Affiliations

    • Department of Radiation Oncology, The Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA
  • ,
  • Douglas R. Spitz, Ph.D.

      Affiliations

    • Department of Radiation Oncology, The Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA
    • Corresponding Author InformationReprint requests to: Douglas R. Spitz, Ph.D., Free Radical and Radiation Biology Program, Department of Radiation Oncology, B180 Medical Laboratories, University of Iowa, Iowa City, IA 52242. Tel: (319) 335-8019; Fax: (319) 335-8039

Received 22 May 2007 ,Revised 5 July 2007 ,Accepted 6 July 2007.

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 Supported by: NIH RO1-CA100045 (D.R.S.), NIH P01-CA66081 (A.L.S.), NIH P30-CA086862 (B.J.S., M.M.G., R.D.H., D.R.S.), T32 CA078586-08 (M.A.F., A.L.S.), RSNA HPSD0602 (D.M.M.), and the Department of Radiation Oncology at the University of Iowa (D.M.M., K.D., J.M.B.).

 Conflict of interest: none.

PII: S0360-3016(07)03693-0

doi: 10.1016/j.ijrobp.2007.07.2343

International Journal of Radiation Oncology * Biology * Physics
Volume 69, Issue 4 , Pages 1222-1230 , 15 November 2007