International Journal of Radiation Oncology * Biology * Physics
Volume 70, Issue 3 , Pages 685-692 , 1 March 2008

Outcomes of Risk-Adapted Fractionated Stereotactic Radiotherapy for Stage I Non–Small-Cell Lung Cancer

  • Frank J. Lagerwaard, M.D., Ph.D.

      Affiliations

    • Department of Radiation Oncology, VU University Medical Center, Amsterdam, The Netherlands
    • Corresponding Author InformationReprint requests to: Frank J. Lagerwaard, M.D., Ph.D., Department of Radiation Oncology, VU University Medical Center, de Boelelaan 1117, 1006 HV Amsterdam, The Netherlands. Tel: (+31) 20-4440414; Fax: (+31) 20-4440410
  • ,
  • Cornelis J.A. Haasbeek, M.D.

      Affiliations

    • Department of Radiation Oncology, VU University Medical Center, Amsterdam, The Netherlands
  • ,
  • Egbert F. Smit, M.D., Ph.D.

      Affiliations

    • Department of Pulmonary Diseases, VU University Medical Center, Amsterdam, The Netherlands
  • ,
  • Ben J. Slotman, M.D., Ph.D.

      Affiliations

    • Department of Radiation Oncology, VU University Medical Center, Amsterdam, The Netherlands
  • ,
  • S. Senan, M.R.C.P., F.R.C.R., Ph.D.

      Affiliations

    • Department of Radiation Oncology, VU University Medical Center, Amsterdam, The Netherlands

Received 15 September 2007 ,Accepted 31 October 2007.

  • Image Result

    Overall (a), disease-free (b), local progression free (c), regional progression-free (d), and distant progression-free survival in 206 patients.

    Overall (a), disease-free (b), local progression free (c), regional progression-free (d), and distant progression-free survival in 206 patients.

  • Image Result

    Disease-free survival for T1 and T2 tumors.

    Disease-free survival for T1 and T2 tumors.

  • Image Result

    Stereotactic radiotherapy (SRT) planning for a peripheral T2 tumor, with the high-dose area adjacent to the thoracic wall (left). The right panel shows rib fractures 2 years after SRT, in the absence

    Stereotactic radiotherapy (SRT) planning for a peripheral T2 tumor, with the high-dose area adjacent to the thoracic wall (left). The right panel shows rib fractures 2 years after SRT, in the absence of local tumor progression.

 Note—An online CME test for this article can be taken at http://asro.astro.org under Continuing Education.

 Conflict of interest: none.

PII: S0360-3016(07)04468-9

doi: 10.1016/j.ijrobp.2007.10.053

International Journal of Radiation Oncology * Biology * Physics
Volume 70, Issue 3 , Pages 685-692 , 1 March 2008