International Journal of Radiation Oncology * Biology * Physics
Volume 71, Issue 5 , Pages 1372-1380, 1 August 2008

Phase II Pilot Study of Bevacizumab in Combination with Temozolomide and Regional Radiation Therapy for Up-Front Treatment of Patients With Newly Diagnosed Glioblastoma Multiforme: Interim Analysis of Safety and Tolerability

  • Albert Lai, M.D., Ph.D.

      Affiliations

    • Department of Neurology, David Geffen School of Medicine at University of California–Los Angeles, Los Angeles, CA
    • Corresponding Author InformationReprint requests to: Albert Lai, M.D., Ph.D., UCLA Neuro-Oncology Program, Department of Neurology, David Geffen School of Medicine at UCLA, 710 Westwood Plaza, Suite 1-230 RNRC, Los Angeles, CA 90095. Tel: (310) 825-5321; Fax: (310) 825-0644
  • ,
  • Emese Filka

      Affiliations

    • Department of Neurology, David Geffen School of Medicine at University of California–Los Angeles, Los Angeles, CA
  • ,
  • Bruce McGibbon, M.D.

      Affiliations

    • Department of Radiation Oncology, David Geffen School of Medicine at University of California–Los Angeles, Los Angeles, CA
  • ,
  • Phioanh Leia Nghiemphu, M.D.

      Affiliations

    • Department of Neurology, David Geffen School of Medicine at University of California–Los Angeles, Los Angeles, CA
  • ,
  • Carrie Graham

      Affiliations

    • Department of Neurology, David Geffen School of Medicine at University of California–Los Angeles, Los Angeles, CA
  • ,
  • William H. Yong, M.D.

      Affiliations

    • Department of Pathology, David Geffen School of Medicine at University of California–Los Angeles, Los Angeles, CA
  • ,
  • Paul Mischel, M.D.

      Affiliations

    • Department of Pathology, David Geffen School of Medicine at University of California–Los Angeles, Los Angeles, CA
  • ,
  • Linda M. Liau, M.D., Ph.D.

      Affiliations

    • Department of Neurosurgery, David Geffen School of Medicine at University of California–Los Angeles, Los Angeles, CA
  • ,
  • Marvin Bergsneider, M.D.

      Affiliations

    • Department of Neurosurgery, David Geffen School of Medicine at University of California–Los Angeles, Los Angeles, CA
  • ,
  • Whitney Pope, M.D., Ph.D.

      Affiliations

    • Department of Radiology, David Geffen School of Medicine at University of California–Los Angeles, Los Angeles, CA
  • ,
  • Michael Selch, M.D.

      Affiliations

    • Department of Radiation Oncology, David Geffen School of Medicine at University of California–Los Angeles, Los Angeles, CA
  • ,
  • Tim Cloughesy, M.D.

      Affiliations

    • Department of Neurology, David Geffen School of Medicine at University of California–Los Angeles, Los Angeles, CA

Received 4 October 2007; received in revised form 29 November 2007; accepted 30 November 2007. published online 20 March 2008.

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 Conflict of interest: Drs. Lai and Dr. Cloughesy have served on the Scientific Advisory Board of Genentech.

PII: S0360-3016(07)04746-3

doi:10.1016/j.ijrobp.2007.11.068

International Journal of Radiation Oncology * Biology * Physics
Volume 71, Issue 5 , Pages 1372-1380, 1 August 2008