International Journal of Radiation Oncology * Biology * Physics
Volume 72, Issue 2 , Pages 398-403 , 1 October 2008

Stereotactic Body Radiotherapy for Oligometastatic Lung Tumors

  • Yoshiki Norihisa, M.D.

      Affiliations

    • Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, Kyoto, Japan
    • ,
  • Yasushi Nagata, M.D., Ph.D.

      Affiliations

    • Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, Kyoto, Japan
    • Corresponding Author InformationReprint requests to: Yasushi Nagata, M.D., Ph.D., Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, 54 Shogoin-Kawahara-Cho, Sakyo-Ku, Kyoto 606-8507, Japan. Tel: (+81) 75-751-3762; Fax: (+81) 75-751-3418
    • ,
  • Kenji Takayama, M.D.

      Affiliations

    • Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, Kyoto, Japan
    • ,
  • Yukinori Matsuo, M.D., Ph.D.

      Affiliations

    • Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, Kyoto, Japan
    • ,
  • Takashi Sakamoto, M.D.

      Affiliations

    • Department of Radiation Oncology, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan
    • ,
  • Masato Sakamoto, M.D.

      Affiliations

    • Department of Radiology, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Japan
    • ,
  • Takashi Mizowaki, M.D., Ph.D.

      Affiliations

    • Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, Kyoto, Japan
    • ,
  • Shinsuke Yano, B.S.

      Affiliations

    • Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, Kyoto, Japan
    • ,
  • Masahiro Hiraoka, M.D., Ph.D.

      Affiliations

    • Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, Kyoto, Japan

Received 5 February 2007 ,Revised 27 December 2007 ,Accepted 3 January 2008.

References 

  1. Uematsu M, Shioda A, Tahara K, et al. Focal, high dose, and fractionated modified stereotactic radiation therapy for lung carcinoma patients: A preliminary experience. Cancer. 1998;82:1062–1070
  2. Nakagawa K, Aoki Y, Tago M, et al. Megavoltage CT-assisted stereotactic radiosurgery for thoracic tumors: Original research in the treatment of thoracic neoplasms. Int J Radiat Oncol Biol Phys. 2000;48:449–457
  3. Wulf J, Hadinger U, Oppitz U, et al. Stereotactic radiotherapy of extracranial targets: CT-simulation and accuracy of treatment in the stereotactic body frame. Radiother Oncol. 2000;57:225–236
  4. Hara R, Itami J, Kondo T, et al. Stereotactic single high dose irradiation of lung tumors under respiratory gating. Radiother Oncol. 2002;63:159–163
  5. Nagata Y, Negoro Y, Aoki T, et al. Clinical outcomes of 3D conformal hypofractionated single high-dose radiotherapy for one or two lung tumors using a stereotactic body frame. Int J Radiat Oncol Biol Phys. 2002;52:1041–1046
  6. Hof H, Herfarth KK, Munter M, et al. Stereotactic single-dose radiotherapy of stage I non-small-cell lung cancer (NSCLC). Int J Radiat Oncol Biol Phys. 2003;56:335–341
  7. Lee SW, Choi EK, Park HJ, et al. Stereotactic body frame based fractionated radiosurgery on consecutive days for primary or metastatic tumors in the lung. Lung Cancer. 2003;40:309–315
  8. Onimaru R, Shirato H, Shimizu S, et al. Tolerance of organs at risk in small-volume, hypofractionated, image-guided radiotherapy for primary and metastatic lung cancers. Int J Radiat Oncol Biol Phys. 2003;56:126–135
  9. Onishi H, Kuriyama K, Komiyama T, et al. A new irradiation system for lung cancer combining linear accelerator, computed tomography, patient self-breath-holding, and patient-directed beam-control without respiratory monitoring devices. Int J Radiat Oncol Biol Phys. 2003;56:14–20
  10. Singh D, Yi WS, Brasacchio RA, et al. Is there a favorable subset of patients with prostate cancer who develop oligometastases?. Int J Radiat Oncol Biol Phys. 2004;58:3–10
  11. Kavanagh BD, McGarry RC, Timmerman RD. Extracranial radiosurgery (stereotactic body radiation therapy) for oligometastases. Semin Radiat Oncol. 2006;16:77–84
  12. Yang JC, Abad J, Sherry R. Treatment of oligometastases after successful immunotherapy. Semin Radiat Oncol. 2006;16:131–135
  13. Rubin P, Brasacchio R, Katz A. Solitary metastases: Illusion versus reality. Semin Radiat Oncol. 2006;16:120–130
  14. Wulf J, Haedinger U, Oppitz U, et al. Stereotactic radiotherapy for primary lung cancer and pulmonary metastases: A noninvasive treatment approach in medically inoperable patients. Int J Radiat Oncol Biol Phys. 2004;60:186–196
  15. Onishi H, Araki T, Shirato H, et al. Stereotactic hypofractionated high-dose irradiation for stage I nonsmall cell lung carcinoma: Clinical outcomes in 245 subjects in a Japanese multiinstitutional study. Cancer. 2004;101:1623–1631
  16. Nagata Y, Takayama K, Matsuo Y, et al. Clinical outcomes of a phase I/II study of 48 Gy of stereotactic body radiotherapy in 4 fractions for primary lung cancer using a stereotactic body frame. Int J Radiat Oncol Biol Phys. 2005;63:1427–1431
  17. Zimmermann FB, Geinitz H, Schill S, et al. Stereotactic hypofractionated radiation therapy for stage I non-small cell lung cancer. Lung Cancer. 2005;48:107–114
  18. Negoro Y, Nagata Y, Aoki T, et al. The effectiveness of an immobilization device in conformal radiotherapy for lung tumor: Reduction of respiratory tumor movement and evaluation of the daily setup accuracy. Int J Radiat Oncol Biol Phys. 2001;50:889–898
  19. Takayama K, Nagata Y, Negoro Y, et al. Treatment planning of stereotactic radiotherapy for solitary lung tumor. Int J Radiat Oncol Biol Phys. 2005;61:1565–1571
  20. Aoki T, Nagata Y, Negoro Y, et al. Evaluation of lung injury after three-dimensional conformal stereotactic radiation therapy for solitary lung tumors: CT appearance. Radiology. 2004;230:101–108
  21. The International Registry of Lung Metastases. Long-term results of lung metastasectomy: Prognostic analyses based on 5206 cases. J Thorac Cardiovasc Surg. 1997;113:37–49
  22. Asaph JW, Keppel JF, Handy JR, et al. Surgery for second lung cancers. Chest. 2000;118:1621–1625
  23. van Rens MT, Zanen P, de la Riviere AB, et al. Survival after resection of metachronous non-small cell lung cancer in 127 patients. Ann Thorac Surg. 2001;71:309–313
  24. Sakamoto T, Tsubota N, Iwanaga K, et al. Pulmonary resection for metastases from colorectal cancer. Chest. 2001;119:1069–1072
  25. Saito Y, Omiya H, Kohno K, et al. Pulmonary metastasectomy for 165 patients with colorectal carcinoma: A prognostic assessment. J Thorac Cardiovasc Surg. 2002;124:1007–1013
  26. Rena O, Casadio C, Viano F, et al. Pulmonary resection for metastases from colorectal cancer: factors influencing prognosis: Twenty-year experience. Eur J Cardiothorac Surg. 2002;21:906–912
  27. Pfannschmidt J, Muley T, Hoffmann H, et al. Prognostic factors and survival after complete resection of pulmonary metastases from colorectal carcinoma: experiences in 167 patients. J Thorac Cardiovasc Surg. 2003;126:732–739
  28. Inoue M, Ohta M, Iuchi K, et al. Benefits of surgery for patients with pulmonary metastases from colorectal carcinoma. Ann Thorac Surg. 2004;78:238–244
  29. Monteiro A, Arce N, Bernardo J, et al. Surgical resection of lung metastases from epithelial tumors. Ann Thorac Surg. 2004;77:431–437
  30. Kondo H, Okumura T, Ohde Y, et al. Surgical treatment for metastatic malignancies—Pulmonary metastasis: Indications and outcomes. Int J Clin Oncol. 2005;10:81–85

 Supported by Grant-in-Aid H18-014 from the Ministry of Health, Labour and Welfare, Japan and Grant-in-Aid 18390333 from the Ministry of Education and Science, Japan.

 Presented in part at the 46th Annual Meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO), Atlanta, GA, October 3–7, 2004.

 Conflict of interest: none.

PII: S0360-3016(08)00027-8

doi: 10.1016/j.ijrobp.2008.01.002

International Journal of Radiation Oncology * Biology * Physics
Volume 72, Issue 2 , Pages 398-403 , 1 October 2008

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