« Previous
Next »
International Journal of Radiation Oncology * Biology * Physics
Volume 73, Issue 4
, Pages 1033-1042
, 15 March 2009
Prognostic Value of Survivin in Locally Advanced Prostate Cancer: Study Based on RTOG 8610
References
- . A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med. 1997;3:917–921
- . IAP proteins: blocking the road to death's door. Nat Rev Mol Cell Biol. 2002;3:401–410
- Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation. Proc Natl Acad Sci USA. 1999;96:1457–1462
- Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation. Am J Pathol. 1998;152:43–49
- A novel anti-apoptosis gene: Re-expression of survivin messenger RNA as a prognosis marker in non–small-cell lung cancers. J Clin Oncol. 1999;17:2100–2104
- Expression of survivin and its relationship to loss of apoptosis in breast carcinomas. Clin Cancer Res. 2000;6:127–134
- Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer. Cancer Res. 1998;58:5071–5074
- . Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas. Cancer Res. 1998;58:1808–1812
- Inducible nitric oxide synthase and survivin messenger RNA expression in hepatocellular carcinoma. Clin Cancer Res. 2002;8:3131–3136
- Quantitatively determined survivin expression levels are of prognostic value in human gliomas. J Clin Oncol. 2002;20:1063–1068
- Survivin enhances radiation resistance in primary human glioblastoma cells via caspase-independent mechanisms. Oncogene. 2004;23:7494–7506
- Expression and targeting of the apoptosis inhibitor, survivin, in human melanoma. J Invest Dermatol. 1999;113:1076–1081
- Adenovirus-mediated inhibition of survivin expression sensitizes human prostate cancer cells to paclitaxel in vitro and in vivo. Prostate. 2005;64:293–302
- Survivin mediates resistance to antiandrogen therapy in prostate cancer. Oncogene. 2005;24:2474–2482
- Inhibitors of apoptosis proteins in prostate cancer cell lines. Prostate. 2002;51:133–140
- Survivin expression is associated with features of biologically aggressive prostate carcinoma. Cancer. 2004;100:751–757
- Expression of the survivin gene in prostate cancer: correlation with clinicopathological characteristics, proliferative activity and apoptosis. J Urol. 2004;171:1855–1860
- Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function. J Cell Sci. 2002;115:575–585
- . Validating survivin as a cancer therapeutic target. Nat Rev Cancer. 2003;3:46–54
- Identification of a novel splice variant of the human anti-apoptosis gene survivin. Biochem Biophys Res Commun. 2004;314:902–907
- Survivin-deltaEx3 and survivin-2B: Two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties. Cancer Res. 1999;59:6097–6102
- Differential subcellular localization of functionally divergent survivin splice variants. Cell Death Differ. 2002;9:1334–1342
- Distinct in vivo expression patterns of survivin splice variants in renal cell carcinomas. Int J Cancer. 2002;100:30–36
- Molecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosis. J Biol Chem. 2006;281:1286–1295
- Survivin splice variants regulate the balance between proliferation and cell death. Oncogene. 2005;24:1994–2007
- Survivin and Bcl-2 expression in prostatic adenocarcinomas. Arch Pathol Lab Med. 2004;128:39–43
- Phase III radiation therapy oncology group (RTOG) trial 86-10 of androgen deprivation adjuvant to definitive radiotherapy in locally advanced carcinoma of the prostate. Int J Radiat Oncol Biol Phys. 2001;50:1243–1252
- Bcl-2 and bax expression and prostate cancer outcome in men treated with radiotherapy in Radiation Therapy Oncology Group protocol 86-10. Int J Radiat Oncol Biol Phys. 2006;66:25–30
- MDM2 as a predictor of prostate carcinoma outcome: An analysis of Radiation Therapy Oncology Group Protocol 8610. Cancer. 2005;104:962–967
- Activated STAT3 as a correlate of distant metastasis in prostate cancer: a secondary analysis of Radiation Therapy Oncology Group 86-10. Urology. 2007;69:505–509
- A semiquantitative image-analytical method for the recording of dose-response curves in immunocytochemical preparations. J Histochem Cytochem. 1999;47:411–420
- . Non parametric estimation from incomplete observations. J Am Stat Assoc. 1958;53:457–816
- . A class of K-sample tests for comparing the cumulative incidence of a competing risk. Ann Statist. 1988;161141–161154
- Early initiation of salvage hormone therapy influences survival in patients who failed initial radiation for locally advanced prostate cancer: A secondary analysis of RTOG protocol 86-10. Int J Radiat Oncol Biol Phys. 2006;64:1162–1167
- Short-term neoadjuvant androgen deprivation therapy and external-beam radiotherapy for locally advanced prostate cancer: Long-term results of RTOG 8610. J Clin Oncol. 2008;26:585–591
- . Radiation and hormonal therapy for locally advanced and clinically localized prostate cancer. Urology. 2002;60:32–38
- Survivin expression in tumor cell nuclei is predictive of a favorable prognosis in gastric cancer patients. Cancer Lett. 2001;163:109–116
- Prognostic importance of survivin in breast cancer. Br J Cancer. 2003;88:1077–1083
- Survivin expression in human osteosarcoma is a marker for survival. Eur J Surg Oncol. 2003;29:379–382
- Immunohistochemical localization of the IAP protein survivin in bladder mucosa and transitional cell carcinoma. Appl Immunohistochem Mol Morphol. 2002;10:134–138
- Nuclear and cytoplasmic expression of survivin in 67 surgically resected pancreatic cancer patients. Br J Cancer. 2005;92:2225–2232
- Survivin expression in hepatocellular carcinoma: Correlation with proliferation, prognostic parameters, and outcome. Mod Pathol. 2004;17:1378–1385
- Survivin promotes cell proliferation in human hepatocellular carcinoma. Hepatology. 2000;31:1080–1085
- Prognostic value of nuclear survivin expression in oesophageal squamous cell carcinoma. Br J Cancer. 2003;88:115–119
- Nuclear survivin expression in mantle cell lymphoma is associated with cell proliferation and survival. Am J Pathol. 2004;164:501–510
- Survivin gene expression in early-stage non-small cell lung cancer. J Pathol. 2003;200:620–626
- Survivin expression in ovarian cancer and its correlation with clinico-pathological, surgical and apoptosis-related parameters. Br J Cancer. 2005;92:271–277
- . Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis. Mol Biol Cell. 2003;14:3325–3341
- IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res. 1998;58:5315–5320
- Expression of different survivin variants in gastric carcinomas: First clues to a role of survivin-2B in tumour progression. Br J Cancer. 2002;86:737–743
Supported by Radiation Therapy Oncology Group Grant U10CA21661, Community Clinical Oncology Program Grant U10CA37422, and Grants Stat U10CA32115 from the National Cancer Institute to the Radiation Therapy Oncology Group and the Pennsylvania Department of Health and R01 CA101984-01 (both to A. Pollack).
Conflict of interest: none.
PII: S0360-3016(08)02473-5
doi: 10.1016/j.ijrobp.2008.06.1489
© 2009 Elsevier Inc. All rights reserved.
« Previous
Next »
International Journal of Radiation Oncology * Biology * Physics
Volume 73, Issue 4
, Pages 1033-1042
, 15 March 2009
