International Journal of Radiation Oncology * Biology * Physics
Volume 74, Issue 1 , Pages 9-14 , 1 May 2009

Clinical Significance of Postradiotherapy [18F]-Fluorodeoxyglucose Positron Emission Tomography Imaging in Management of Head-and-Neck Cancer—A Long-Term Outcome Report

  • Min Yao, M.D., Ph.D.

      Affiliations

    • Department of Radiation Oncology, University Hospitals Case Medical Center, Cleveland, OH
    • Corresponding Author InformationReprint requests to: Min Yao, M.D., Ph.D., Department of Radiation Oncology, University Hospitals, Case Medical Center, 11100 Euclid Ave., Cleveland, OH 44106. Tel: (216) 844-2537; Fax: (216) 844-2005
    • ,
  • Russell B. Smith, M.D.

      Affiliations

    • Department of Otolaryngology-Head and Neck Surgery, University of Nebraska Medical Center, Omaha, NE
    • ,
  • Henry T. Hoffman, M.D.

      Affiliations

    • Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, IA
    • ,
  • Gerry F. Funk, M.D.

      Affiliations

    • Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, IA
    • ,
  • Minggen Lu, Ph.D.

      Affiliations

    • University of Nevada at Reno School of Public Health, Reno, NV
    • ,
  • Yusuf Menda, M.D.

      Affiliations

    • Department of Radiology, University of Iowa, Iowa City, IA
    • ,
  • Michael M. Graham, M.D., Ph.D.

      Affiliations

    • Department of Radiology, University of Iowa, Iowa City, IA
    • ,
  • John M. Buatti, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Iowa, Iowa City, IA

Received 16 June 2008 ,Revised 16 July 2008 ,Accepted 20 July 2008.

References 

  1. Jemal A, Murray T, Samuels A, et al. Cancer statistics, 2003. CA Cancer J Clin. 2003;53:5–26
  2. Menda Y, Graham MM. Update on 18F-fluorodeoxyglucose/positron emission tomography and positron emission tomography/computed tomography imaging of squamous head and neck cancers. Semin Nucl Med. 2005;35:214–219
  3. Fleming AJ, Johansen ME. The clinician's expectations from the use of positron emission tomography/computed tomography scanning in untreated and treated head and neck cancer patients. Curr Opin Otolaryngol Head Neck Surg. 2008;16:127–134
  4. Agarwal V, Branstetter BF, Johnson JT. Indications for PET/CT in the head and neck. Otolaryngol Clin North Am. 2008;41:23–49
  5. Yao M, Graham MM, Smith RB, et al. Value of FDG PET in assessment of treatment response and surveillance in head-and-neck cancer patients after intensity modulated radiation treatment: A preliminary report. Int J Radiat Oncol Biol Phys. 2004;60:1410–1418
  6. Yao M, Graham MM, Hoffman HT, et al. The role of post-radiation therapy FDG PET in prediction of necessity for post-radiation therapy neck dissection in locally advanced head-and-neck squamous cell carcinoma. Int J Radiat Oncol Biol Phys. 2004;59:1001–1010
  7. Yao M, Luo P, Hoffman HT, et al. Pathology and FDG PET correlation of residual lymph nodes in head and neck cancer after radiation treatment. Am J Clin Oncol. 2007;30:264–270
  8. Yao M, Smith RB, Graham MM, et al. The role of FDG PET in management of neck metastasis from head-and-neck cancer after definitive radiation treatment. Int J Radiat Oncol Biol Phys. 2005;63:991–999
  9. Yao M, Hoffman HT, Chang K, et al. Is planned neck dissection necessary for head and neck cancer after intensity-modulated radiotherapy?. Int J Radiat Oncol Biol Phys. 2007;68:707–713
  10. Dornfeld K, Hopkins S, Simmons J, et al. Posttreatment FDG-PET uptake in the supraglottic and glottic larynx correlates with decreased quality of life after chemoradiotherapy. Int J Radiat Oncol Biol Phys. 2008;71:386–392
  11. Yao M, Dornfeld KJ, Buatti JM, et al. Intensity-modulated radiation treatment for head-and-neck squamous cell carcinoma—The University of Iowa experience. Int J Radiat Oncol Biol Phys. 2005;63:410–421
  12. Mendenhall WM, Villaret DB, Amdur RJ, et al. Planned neck dissection after definitive radiotherapy for squamous cell carcinoma of the head and neck. Head Neck. 2002;24:1012–1018
  13. Pellitteri PK, Ferlito A, Rinaldo A, et al. Planned neck dissection following chemoradiotherapy for advanced head and neck cancer: Is it necessary for all?. Head Neck. 2006;28:166–175
  14. Porceddu SV, Jarmolowski E, Hicks RJ, et al. Utility of positron emission tomography for the detection of disease in residual neck nodes after (chemo)radiotherapy in head and neck cancer. Head Neck. 2005;27:175–181
  15. Nayak JV, Daamen N, Ferris RL, et al. Deferring planned neck dissection after chemoradiation therapy in stage IV head and neck cancer: The utility of PET/CT. [Abstract] Arch Otolaryngol Head Neck Surg. 2006;132:843;Abstract S023
  16. Ware RE, Matthews JP, Hicks RJ, et al. Usefulness of fluosine-18 fluorodeoxyglucose positron emission tomography in patients with a residual structural abnormality after definitive treatment for squamous cell carcinoma of the head and neck. Head Neck. 2004;26:1008–1017
  17. National Comprehensive Cancer Network. NCCN clinical practice guideline in oncology: Head and neck cancers. Version 1. 2007. Available from: http://www.nccn.org/professionals/physician_gls/PDF/head-and-neck.pdf. Accessed June 10, 2008.
  18. Ritoe SC, Krabbe PFM, Kaanders JHAM, et al. Value of routine follow-up for patients cured of laryngeal carcinoma. Cancer. 2004;101:1382–1389
  19. Schwartz DL, Barker J, Chansky K, et al. Postradiotherapy surveillance practice for head and neck squamous cell carcinoma—Too much for too little?. Head Neck. 2003;25:990–999
  20. Cooney TR, Poulsen MG. Is routine follow-up useful after combined-modality therapy for advanced head and neck cancer?. Arch Otolaryngol Head Neck Surg. 1999;125:379–382
  21. Greven KM, Williams DW, McGuirt WF, et al. Serial positron emission tomography scans following radiation therapy of patients with head and neck cancer. Head Neck. 2001;23:942–946
  22. Ryan WR, Fee WE, Le QT. Positron-emission tomography for surveillance of head and neck cancer. Laryngoscope. 2005;115:645–650

 Presented, in part, at the 49th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, Los Angeles, CA, October 28 to November 1, 2007.

 Conflict of interest: none.

PII: S0360-3016(08)03039-3

doi: 10.1016/j.ijrobp.2008.07.019

International Journal of Radiation Oncology * Biology * Physics
Volume 74, Issue 1 , Pages 9-14 , 1 May 2009

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