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Volume 74, Issue 1 , Pages 73-80 , 1 May 2009

Potential Effect of Robust and Simple IMRT Approach for Left-Sided Breast Cancer on Cardiac Mortality

Frank Lohr, M.D.
- Department of Radiation Oncology, Mannheim University Medical Center, University of Heidelberg, Mannheim, Germany
- Reprint requests to: Frank Lohr, M.D., Klinik für Strahlentherapie und Radioonkologie, Universitätsklinikum Mannheim, Universität Heidelberg, Theodor-Kutzer Ufer 1-3, Mannheim 68167 Germany. Tel: (0621) 383-3530; Fax: (0621) 383-3493
Mostafa El-Haddad, M.D., F.R.C.R.
- Department of Radiation Oncology, Mannheim University Medical Center, University of Heidelberg, Mannheim, Germany
- Department of Oncology, Kasr-El-Einy Hospital, Cairo University, Cairo, Egypt
Barbara Dobler, Ph.D.
- Department of Radiation Oncology, Mannheim University Medical Center, University of Heidelberg, Mannheim, Germany
- Department of Radiotherapy, Regensburg University Medical Center, Regensburg, Germany
Roland Grau, M.D.
- Department of Radiation Oncology, Mannheim University Medical Center, University of Heidelberg, Mannheim, Germany
Hans-Joerg Wertz, M.Sc.
- Department of Radiation Oncology, Mannheim University Medical Center, University of Heidelberg, Mannheim, Germany
Uta Kraus-Tiefenbacher, M.D.
- Department of Radiation Oncology, Mannheim University Medical Center, University of Heidelberg, Mannheim, Germany
Volker Steil, M.Sc.
- Department of Radiation Oncology, Mannheim University Medical Center, University of Heidelberg, Mannheim, Germany
Yasser Abo Madyan, M.D.
- Department of Radiation Oncology, Mannheim University Medical Center, University of Heidelberg, Mannheim, Germany
- Department of Oncology, Kasr-El-Einy Hospital, Cairo University, Cairo, Egypt
Frederik Wenz, M.D.
- Department of Radiation Oncology, Mannheim University Medical Center, University of Heidelberg, Mannheim, Germany

Received 21 April 2008 ,Revised 17 July 2008 ,Accepted 20 July 2008.

Dose distributions in transversal, coronal, and sagittal plane for (a) intensity-modulated radiotherapy and (b) conformal three-dimensional plans.

Dose distributions in transversal, coronal, and sagittal plane for (a) intensity-modulated radiotherapy and (b) conformal three-dimensional plans.
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Heart dose–volume histograms of all 14 patient plans for (a) intensity-modulated radiotherapy and (b) three-dimensional conformal radiotherapy. Although heart volume treated to doses >30 Gy was minima

Heart dose–volume histograms of all 14 patient plans for (a) intensity-modulated radiotherapy and (b) three-dimensional conformal radiotherapy. Although heart volume treated to doses >30 Gy was minimal for intensity-modulated radiotherapy plans, mean and median heart dose were increased compared with three-dimensional conformal radiotherapy plans.
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Dose–volume histograms for original plan with dose–volume histograms after 1-cm movement of isocenter anteriorly, posteriorly, and caudally superimposed, without major effects on dose distribution.

Dose–volume histograms for original plan with dose–volume histograms after 1-cm movement of isocenter anteriorly, posteriorly, and caudally superimposed, without major effects on dose distribution.
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