International Journal of Radiation Oncology * Biology * Physics
Volume 72, Issue 4 , Pages 1188-1197, 15 November 2008

Replication-Dependent Radiosensitization of Human Glioma Cells by Inhibition of Poly(ADP-Ribose) Polymerase: Mechanisms and Therapeutic Potential

  • Fiona A. Dungey, B.Sc.

      Affiliations

    • Genome Damage and Stability Centre, University of Sussex, Brighton, United Kingdom
  • ,
  • Dana A. Löser, M.Sc.

      Affiliations

    • Genome Damage and Stability Centre, University of Sussex, Brighton, United Kingdom
  • ,
  • Anthony J. Chalmers, F.R.C.R., Ph.D.

      Affiliations

    • Genome Damage and Stability Centre, University of Sussex, Brighton, United Kingdom
    • Brighton and Sussex Medical School, University of Sussex, Brighton, United Kingdom
    • Corresponding Author InformationReprint requests to: Anthony J. Chalmers, F.R.C.R., Ph.D., Brighton and Sussex Medical School, Genome Damage and Stability Centre, University of Sussex, Brighton BN1 9PX United Kingdom. Tel: (+44) 127-387-6637; Fax: (+44) 127-367-8121

Received 10 June 2008; received in revised form 23 July 2008; accepted 24 July 2008.

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 Funded by the Medical Research Council.

 Conflict of interest: none.

PII: S0360-3016(08)03170-2

doi:10.1016/j.ijrobp.2008.07.031

International Journal of Radiation Oncology * Biology * Physics
Volume 72, Issue 4 , Pages 1188-1197, 15 November 2008