International Journal of Radiation Oncology * Biology * Physics
Volume 73, Issue 5 , Pages 1397-1403 , 1 April 2009

Designing Targets for Elective Nodal Irradiation in Lung Cancer Radiotherapy: A Planning Study

  • Lucyna Kepka, M.D.

      Affiliations

    • Department of Radiation Oncology, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland
  • ,
  • Daniel Tatro

      Affiliations

    • Department of Radiation Oncology, University of Michigan, Ann Arbor, MI
  • ,
  • Jean M. Moran, Ph.D.

      Affiliations

    • Department of Radiation Oncology, University of Michigan, Ann Arbor, MI
  • ,
  • Leslie E. Quint, M.D.

      Affiliations

    • Department of Radiology, University of Michigan, Ann Arbor, MI
  • ,
  • James A. Hayman, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Michigan, Ann Arbor, MI
  • ,
  • Randall K. Ten Haken, Ph.D.

      Affiliations

    • Department of Radiation Oncology, University of Michigan, Ann Arbor, MI
  • ,
  • Feng-Ming Kong, M.D., Ph.D.

      Affiliations

    • Department of Radiation Oncology, University of Michigan, Ann Arbor, MI
    • Corresponding Author InformationReprint requests to: Feng-Ming Kong, M.D., Ph.D., Department of Radiation Oncology, University of Michigan, UH-B2C490, Box 0010, 1500 East Medical Center Drive, Ann Arbor, MI 48109; Fax: (734) 763-7370

Received 29 April 2008 ,Revised 14 July 2008 ,Accepted 19 July 2008.

References 

  1. Chapet O, Kong F-M, Quint LE, et al. CT-based definition of thoracic lymph node stations: An atlas from the University of Michigan. Int J Radiat Oncol Biol Phys. 2005;63:170–178
  2. Senan S, Le Pechoux C, Spoelstra F, et al. A need to standardize post-operative radiotherapy (PORT) fields used for non-small cell lung cancer (NSCLC): Analysis of an international dummy-run study. J Thoracic Oncol. 2007;8:S308
  3. Radiation Therapy Oncology Group. RTOG 94-10: A Three-Arm Phase III Study of Concomitant versus Sequential Chemotherapy and Thoracic Radiotherapy for Patients with Locally Advanced Inoperable Non-Small Cell Lung Cancer. Available at http://www.rtog.org/members/protocols/94-10/94-10.pdf.
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  8. Madu CN, Quint DJ, Normolle DP, et al. Definition of the supraclavicular and infraclavicular nodes: Implications for three-dimensional CT-based conformal radiation therapy. Radiology. 2001;221:333–339
  9. Dijkema IM, Hofman P, Raaijmakers CPJ, et al. Loco-regional conformal radiotherapy of the breast: Delineation of the regional lymph node clinical target volumes in treatment position. Radiother Oncol. 2004;71:287–295
  10. Yuan S, Meng X, Yu J, et al. Determining optimal clinical target volume margins on the basis of microscopic extracapsular extension of metastatic nodes in patients with non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2002;67:727–734
  11. Hurkmans CW, Remeijer P, Lebesque JV, Mijnheer BJ. Set-up verification using portal imaging; review of current clinical practice. Radiother Oncol. 2001;58:105–120
  12. Bowden P, Fisher R, Mac Manus M, et al. Measurement of lung tumor volumes using three-dimensional computer planning software. Int J Radiat Oncol Biol Phys. 2002;53:566–573
  13. Kepka L, Bujko K, Garmol D, et al. Delineation variation of lymph node stations for treatment planning in lung cancer radiotherapy. Radiother Oncol. 2007;85:450–455

 This work was supported by a UICC International Cancer Technology Transfer (ICR/07/043/2007) fellowship.

 Conflict of interest: none.

PII: S0360-3016(08)03176-3

doi: 10.1016/j.ijrobp.2008.07.036

International Journal of Radiation Oncology * Biology * Physics
Volume 73, Issue 5 , Pages 1397-1403 , 1 April 2009