International Journal of Radiation Oncology * Biology * Physics
Volume 74, Issue 1 , Pages 21-28 , 1 May 2009

A Broadly Adaptive Array of Dose-Constraint Templates for Planning of Intensity-Modulated Radiation Therapy for Advanced T-Stage Nasopharyngeal Carcinoma

  • Ricky Ming-Chun Chau, Ph.D.

      Affiliations

    • Department of Clinical Oncology, Prince of Wales Hospital, Hong Kong, SAR, China
    • Corresponding Author InformationReprint requests to: Ming-Chun Chau, Ph.D., Clinical Oncology Department, Prince of Wales Hospital, Ngan Shing Street, Shatin, Hong Kong, SAR, China. Tel: (852) 2632-1303; Fax: (852) 2632-4558.
    • ,
  • Sing-Fai Leung, M.D.

      Affiliations

    • State Key Laboratories of Southern China, Sir YK Pao Cancer Center, Department of Clinical Oncology, The Chinese University of Hong Kong, Hong Kong SAR, China
    • ,
  • Michael Koon-Ming Kam, F.R.C.R.

      Affiliations

    • Department of Clinical Oncology, Prince of Wales Hospital, Hong Kong, SAR, China
    • ,
  • Kin-Yin Cheung, Ph.D.

      Affiliations

    • Department of Clinical Oncology, Prince of Wales Hospital, Hong Kong, SAR, China
    • ,
  • Wing-Hon Kwan, F.R.C.R.

      Affiliations

    • Department of Clinical Oncology, Prince of Wales Hospital, Hong Kong, SAR, China
    • ,
  • Kwok-Hung Yu, F.R.C.R.

      Affiliations

    • Department of Clinical Oncology, Prince of Wales Hospital, Hong Kong, SAR, China
    • ,
  • Kwok-Wing Chiu, F.R.C.R.

      Affiliations

    • Department of Clinical Oncology, Prince of Wales Hospital, Hong Kong, SAR, China
    • ,
  • Michael Lok-Man Cheung, M.S.

      Affiliations

    • Department of Clinical Oncology, Prince of Wales Hospital, Hong Kong, SAR, China
    • ,
  • Anthony Tak-Cheung Chan, M.D.

      Affiliations

    • State Key Laboratories of Southern China, Sir YK Pao Cancer Center, Department of Clinical Oncology, The Chinese University of Hong Kong, Hong Kong SAR, China

Received 31 May 2007 ,Revised 22 July 2008 ,Accepted 22 July 2008.

References 

  1. Chao KS, Low DA, Perez CA, et al. Intensity-modulated radiation therapy in head and neck cancers: The Mallinckrodt experience. Int J Cancer. 2000;90:92–103
  2. Xia P, Fu KK, Wong GW, et al. Comparison of treatment plans involving intensity-modulated radiotherapy for nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 2000;48:329–337
  3. Sultanem K, Shu HK, Xia P, et al. Three-dimensional intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: The University of California-San Francisco experience. Int J Radiat Oncol Biol Phys. 2000;48:711–722
  4. Hunt MA, Zelefsky MJ, Wolden S, et al. Treatment planning and delivery of intensity-modulated radiation therapy for primary nasopharynx cancer. Int J Radiat Oncol Biol Phys. 2001;49:623–632
  5. Eisbruch A. Clinical ASPECTS of IMRT for head-and-neck cancer. Med Dosim. 2002;27:99–104
  6. Lee N, Xia P, Quivey JM, et al. Intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: An update of the UCSF experience. Int J Radiat Oncol Biol Phys. 2002;53:12–22
  7. Members of the staff of Memorial Sloan-Kettering Cancer Center. A practical guide to intensity-modulated radiation therapy. Madison, WI: Medical Physics; 2003;
  8. Kam MK, Teo PM, Chau RM, et al. Treatment of nasopharyngeal carcinoma with intensity-modulated radiotherapy: The Hong Kong experience. Int J Radiat Oncol Biol Phys. 2004;60:1440–1450
  9. Garden AS, Morrison WH, Rosenthal DI, et al. Target coverage for head and neck cancers treated with IMRT: Review of clinical experiences. Semin Radiat Oncol. 2004;14:103–109
  10. Porceddu S, Hope G, Wills J, et al. Intensity-modulated radiotherapy: Examples of its utility in head and neck cancer. Australas Radiol. 2004;48:51–57
  11. Kwong DL, Pow EH, Sham JS, et al. Intensity-modulated radiotherapy for early-stage nasopharyngeal carcinoma: A prospective study on disease control and preservation of salivary function. Cancer. 2004;101:1584–1593
  12. Yao M, Dornfeld KJ, Buatti JM, et al. Intensity-modulated radiation treatment for head-and-neck squamous cell carcinoma—The University of Iowa experience. Int J Radiat Oncol Biol Phys. 2005;63:410–421
  13. Wolden SL, Chen WC, Pfister DG, et al. Intensity-modulated radiation therapy (IMRT) for nasopharynx cancer: Update of the Memorial Sloan-Kettering experience. Int J Radiat Oncol Biol Phys. 2006;64:57–62
  14. Xia P, Lee N, Liu YM, et al. A study of planning dose constraints for treatment of nasopharyngeal carcinoma using a commercial inverse treatment planning system. Int J Radiat Oncol Biol Phys. 2004;59:886–896
  15. Chau RMC, Leung SF, Kam MKM, et al. A split-organ delineation approach for dose optimisation for intensity-modulated radiotherapy for advanced T-stage nasopharyngeal carcinoma. Clin Oncol. 2008;20:134–141
  16. Webb S, Nahum AE. A model for calculating tumour control probability in radiotherapy including the effects of inhomogeneous distributions of dose and clonogenic cell density. Phys Med Biol. 1993;38:653–666
  17. Lyman JT, Wolbarst AB. Optimization of radiation therapy, III: A method of assessing complication probability from dose-volume histograms. In press Int J Radiat Oncol Biol Phys. 1987;13:103–109
  18. Chau RMC, Teo PML, Kam MKM, et al. Dosimetric comparison between 2-dimensional radiation therapy and intensity-modulated radiation therapy in treatment of advanced T-stage nasopharyngeal carcinoma: To treat less or more in the planning organ at risk volume of the brainstem and spinal cord. Med Dosim. 2007;32:263–270
  19. Baltas D, Kolotas C, Geramani K, et al. A conformal index (COIN) to evaluate implant quality and dose specification in brachytherapy. Int J Radiat Oncol Biol Phys. 1998;40:515–524
  20. Sanchez-Nieto B, Nahum AE. Bioplan: Software for the biological evaluation of radiotherapy treatment plans. Med Dosim. 2000;25:71–76

 Abstract submitted to the meeting of ASTRO 49th Annual Meeting, October 28–November 1, 2007, Los Angeles, CA.

 Conflict of interest: none.

PII: S0360-3016(08)03181-7

doi: 10.1016/j.ijrobp.2008.07.041

International Journal of Radiation Oncology * Biology * Physics
Volume 74, Issue 1 , Pages 21-28 , 1 May 2009

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