International Journal of Radiation Oncology * Biology * Physics
Volume 73, Issue 1 , Pages 6-8 , 1 January 2009

Timing of Lethality From Gastrointestinal Syndrome in Mice Revisited

  • Jimmy A. Rotolo, Ph.D.

      Affiliations

    • Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, NY
    • ,
  • Richard Kolesnick, M.D.

      Affiliations

    • Laboratory of Signal Transduction, Memorial Sloan-Kettering Cancer Center, New York, NY
    • ,
  • Zvi Fuks, M.D.

      Affiliations

    • Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY
    • Corresponding Author InformationReprint requests to: Zvi Fuks, M.D., Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, 1275 York Ave., New York, NY 10021. Tel: (646) 888-2094; Fax: (212) 794-3188

Received 9 June 2008 ,Revised 2 September 2008 ,Accepted 5 September 2008.

References 

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  12. Okunieff P, Mester M, Wang J, et al. In vivo radioprotective effects of angiogenic growth factors on the small bowel of C3H mice. Radiat Res. 1998;150:204–211
  13. Paris F, Fuks Z, Kang A, et al. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science. 2001;293:293–297
  14. Rotolo JA, Maj JG, Feldman R, et al. Bax and Bak do not exhibit functional redundancy in mediating radiation-induced endothelial apoptosis in the intestinal mucosa. Int J Radiat Oncol Biol Phys. 2008;70:804–815
  15. Mason KA, Withers HR, McBride WH, et al. Comparison of the gastrointestinal syndrome after total-body or total-abdominal irradiation. Radiat Res. 1989;117:480–488
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 Conflict of interest: none.

PII: S0360-3016(08)03428-7

doi: 10.1016/j.ijrobp.2008.09.009

International Journal of Radiation Oncology * Biology * Physics
Volume 73, Issue 1 , Pages 6-8 , 1 January 2009

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