International Journal of Radiation Oncology * Biology * Physics
Volume 74, Issue 4 , Pages 1006-1011 , 15 July 2009

A Phase II Study of Preradiotherapy Chemotherapy Followed by Hyperfractionated Radiotherapy for Newly Diagnosed High-Risk Medulloblastoma/Primitive Neuroectodermal Tumor: A Report From the Children's Oncology Group (CCG 9931)

  • Jeffrey Allen, M.D.

      Affiliations

    • Departments of Pediatrics and Pathology, New York University Medical Center, New York, NY
    • Corresponding Author InformationReprint requests to: Jeffrey Allen, M.D., New York University Medical Center, 160 East 32nd Street, Hassenfeld Clinic, New York, NY 10016. Tel: (212) 263-9907; Fax (212) 263-8410
    • ,
  • Bernadine Donahue, M.D.

      Affiliations

    • Department of Radiation Oncology, Maimonides Medical Center, Brooklyn, NY
    • ,
  • Minesh Mehta, M.D.

      Affiliations

    • Department of Radiation Oncology, Children's Hospital, Madison, WI
    • ,
  • Douglas C. Miller, M.D., Ph.D.

      Affiliations

    • Departments of Pediatrics and Pathology, New York University Medical Center, New York, NY
    • ,
  • Lucy B. Rorke, M.D.

      Affiliations

    • Department of Pathology, Children's Hospital of Philadelphia, Philadelphia, PA
    • ,
  • Regina Jakacki, M.D.

      Affiliations

    • Department of Pediatric Oncology, Children's Hospital, Pittsburgh, PA
    • ,
  • Patricia Robertson, M.D.

      Affiliations

    • Department of Neurology, C.S. Mott Children's Hospital, Ann Arbor, MI
    • ,
  • Richard Sposto, Ph.D.

      Affiliations

    • Departments of Preventive Medicine and Pediatrics (Children's Hospital Los Angeles), Keck School of Medicine at the University of Southern California, Los Angeles, CA
    • ,
  • Emi Holmes, M.S.

      Affiliations

    • Children's Oncology Group Operations Office, Arcadia, CA
    • ,
  • Gilbert Vezina, M.D.

      Affiliations

    • Department of Radiology, National Children's Medical Center, Washington, DC
    • ,
  • Karin Muraszko, M.D.

      Affiliations

    • Department of Neurosurgery, University of Michigan, Ann Arbor, MI
    • ,
  • Diane Puccetti, M.D.

      Affiliations

    • University of Wisconsin Children's Hospital, Madison, WI
    • ,
  • Michael Prados, M.D.

      Affiliations

    • Department of Neurosurgery, University of California, San Francisco, CA
    • ,
  • Ka-Wah Chan, M.D.

      Affiliations

    • Methodist Children's Hospital of South Texas, San Antonio, TX

Received 1 April 2008 ,Revised 15 September 2008 ,Accepted 28 September 2008.

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 Supported by Children's Oncology Group (COG) grant CA 98543. A complete listing of grant support for research conducted by the Children's Cancer Group and the Pediatric Oncology Group before initiation of the COG grant in 2003 is available online at http://www.childrensoncologygroup.org/admin/grantinfo.htm

 Presented in part at the International Society of Pediatric Neurology (Allen J, Prados M, Donahue B, et al. A phase I/II study for newly diagnosed high risk PNET consisting of neoadjuvant chemotherapy followed by hyperfractionated radiotherapy: Preliminary results of CCG 9931. Neurooncology 2000;2:245).

 Conflict of interest: none.

PII: S0360-3016(08)03472-X

doi: 10.1016/j.ijrobp.2008.09.019

International Journal of Radiation Oncology * Biology * Physics
Volume 74, Issue 4 , Pages 1006-1011 , 15 July 2009

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