International Journal of Radiation Oncology * Biology * Physics
Volume 73, Issue 3 , Pages 897-903 , 1 March 2009

The Vascular Endothelial Growth Factor Receptor-2 Tyrosine Kinase Inhibitor Cediranib (Recentin; AZD2171) Inhibits Endothelial Cell Function and Growth of Human Renal Tumor Xenografts

  • Dietmar W. Siemann, Ph.D.

      Affiliations

    • Department of Radiation Oncology, University of Florida, Gainesville, FL
    • Corresponding Author InformationReprint requests to: Dietmar W. Siemann, Ph.D., Department of Radiation Oncology, University of Florida, 2000 S.W. Archer Road, Gainesville, FL 32610. Tel: (352) 265-0287; Fax: (352) 265-0759
    • ,
  • W.D. Brazelle, Ph.D.

      Affiliations

    • Department of Radiation Oncology, University of Florida, Gainesville, FL
    • ,
  • Juliane M. Jürgensmeier, Ph.D.

      Affiliations

    • Cancer Bioscience, AstraZeneca, Alderley Park, Macclesfield, Cheshire, United Kingdom

Received 30 June 2008 ,Revised 3 September 2008 ,Accepted 20 October 2008.

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 Supported in part by a grant from AstraZeneca and US Public Health Service Grant CA089655 from the U.S. National Cancer Institute.

 Conflict of interest: These studies were supported in part by a research grant to Dr. Siemann from AstraZeneca. Dr. Juliane Jürgensmeier is an employee of AstraZeneca.

PII: S0360-3016(08)03673-0

doi: 10.1016/j.ijrobp.2008.10.031

International Journal of Radiation Oncology * Biology * Physics
Volume 73, Issue 3 , Pages 897-903 , 1 March 2009

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