International Journal of Radiation Oncology * Biology * Physics
Volume 73, Issue 4 , Pages 976-979 , 15 March 2009

Major Vault Protein May Affect Nonhomologous End-Joining Repair and Apoptosis Through Ku70/80 and BAX Downregulation in Cervical Carcinoma Tumors

  • Marta Lloret, M.D., Ph.D.

      Affiliations

    • Radiation Oncology Department, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria, Spain
    • Instituto Canario de Investigación del Cáncer, Canary Islands, Spain
    • Corresponding Author InformationReprint requests to: Marta Lloret, M.D., Ph.D., Radiation Oncology, Hospital Universitario Dr. Negrin, Barranco de la Ballena s/n, 35010, Las Palmas de Gran Canaria, Spain. Tel: (00) 34-92-845-0284; Fax: (00) 34-92-844-9127
    • ,
  • Pedro Carlos Lara, M.D., Ph.D.

      Affiliations

    • Radiation Oncology Department, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria, Spain
    • Instituto Canario de Investigación del Cáncer, Canary Islands, Spain
    • ,
  • Elisa Bordón, Ph.D.

      Affiliations

    • Radiation Oncology Department, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria, Spain
    • Instituto Canario de Investigación del Cáncer, Canary Islands, Spain
    • ,
  • Fausto Fontes, B. Pharm.

      Affiliations

    • Instituto Canario de Investigación del Cáncer, Canary Islands, Spain
    • ,
  • Agustin Rey, M.D., Ph.D.

      Affiliations

    • Pathology Department, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria, Spain
    • Instituto Canario de Investigación del Cáncer, Canary Islands, Spain
    • ,
  • Beatriz Pinar, M.D., Ph.D.

      Affiliations

    • Radiation Oncology Department, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria, Spain
    • Instituto Canario de Investigación del Cáncer, Canary Islands, Spain
    • ,
  • Orlando Falcón, M.D., Ph.D.

      Affiliations

    • Instituto Canario de Investigación del Cáncer, Canary Islands, Spain
    • Gynecological Oncology Department, Hospital Universitario Materno-Infantil, Las Palmas de Gran Canaria, Spain

Received 16 November 2008 ,Accepted 18 November 2008.

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 This work was subsidized by Fondo de Investigaciones Sanitarias Grants 1035/98 and 0855/01. E. Bordón and F. Fontes were supported by an educational grant from the Instituto Canario de Investigación del Cáncer.

 Conflict of interest: none.

PII: S0360-3016(08)03791-7

doi: 10.1016/j.ijrobp.2008.11.013

International Journal of Radiation Oncology * Biology * Physics
Volume 73, Issue 4 , Pages 976-979 , 15 March 2009

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