International Journal of Radiation Oncology * Biology * Physics
Volume 74, Issue 3 , Pages 920-927 , 1 July 2009

Evaluation of Linear Accelerator Gating With Real-Time Electromagnetic Tracking

  • Ryan L. Smith, B.S.

      Affiliations

    • Washington University School of Medicine, St. Louis, MO
  • ,
  • Kristen Lechleiter, M.S.

      Affiliations

    • Washington University School of Medicine, St. Louis, MO
  • ,
  • Kathleen Malinowski, M.S.

      Affiliations

    • Washington University School of Medicine, St. Louis, MO
  • ,
  • D.M. Shepard, Ph.D.

      Affiliations

    • Swedish Cancer Institute, Seattle, WA
  • ,
  • D.J. Housley, B.S.

      Affiliations

    • Swedish Cancer Institute, Seattle, WA
  • ,
  • M. Afghan, Ph.D.

      Affiliations

    • Swedish Cancer Institute, Seattle, WA
  • ,
  • Jeff Newell, M.S.

      Affiliations

    • Calypso Medical Technologies, Seattle, WA
  • ,
  • Jay Petersen, B.S.

      Affiliations

    • Calypso Medical Technologies, Seattle, WA
  • ,
  • Brian Sargent, B.S.

      Affiliations

    • Calypso Medical Technologies, Seattle, WA
  • ,
  • Parag Parikh, M.D.

      Affiliations

    • Washington University School of Medicine, St. Louis, MO
    • Corresponding Author InformationReprint requests to: Parag J. Parikh, M.D., Department of Radiation Oncology, Washington University School of Medicine, 4921 Parkview Pl., Lower Level, St. Louis, MO 63110. Tel: (314) 362-8525; Fax: (314) 362-8521

Received 25 April 2008 ,Revised 20 January 2009 ,Accepted 23 January 2009.

References 

  1. Langen KM, Jones DT. Organ motion and its management. Int J Radiat Oncol Biol Phys. 2001;50:265–278
  2. Ramsey CR, Cordrey IL, Oliver AL. A comparison of beam characteristics for gated and nongated clinical x-ray beams. Med Phys. 1999;26:2086–2091
  3. Pan T, Lee TY, Rietzel E, et al. 4D-CT imaging of a volume influenced by respiratory motion on multi-slice CT. Med Phys. 2004;31:333–340
  4. Shirato H, Shimizu S, Kunieda T, et al. Physical aspects of a real-time tumor-tracking system for gated radiotherapy. Int J Radiat Oncol Biol Phys. 2000;48:1187–1195
  5. Margeras G, Yorke E, Rosenzweig K. Initial clinical evaluation of a respiratory gating radiotherapy system. Proceedings of the 22nd annual EMBS International Conference, July 23–28, 2000, Chicago, IL.
  6. Kini VR, Vedam SS, Keall PJ, et al. Patient training in respiratory-gated radiotherapy. Med Dosim. 2003;28:7–11
  7. Kubo HD, Len PM , Minohara S, et al. Breathing-synchronized radiotherapy program at the University of California Davis Cancer Center. Med Phys. 2000;27:346–353
  8. Berson AM, Emery R, Rodriguez L, et al. Clinical experience using respiratory gated radiation therapy: Comparison of free-breathing and breath-hold techniques. Int J Radiat Oncol Biol Phys. 2004;60:419–426
  9. Kubo HD, Hill BC. Respiration gated radiotherapy treatment: A technical study. Phys Med Biol. 1996;41:83–91
  10. Gierga DP, Brewer J, Sharp GC, et al. The correlation between internal and external markers for abdominal tumors: Implications for respiratory gating. Int J Radiat Oncol Biol Phys. 2005;62:1551–1558
  11. Margeras GS, Yorke E. Deep inspiration breath hold and respiratory gating strategies for reducing organ motion in radiation treatment. Semin Radiat Oncol. 2004;14:65–75
  12. Koch N, Liu HH, Starkschall G, et al. Evaluation of internal lung motion for respiratory-gated radiotherapy using MRI: Part I—Correlating internal lung motion with skin fiducial motion. Int J Radiat Oncol Biol Phys. 2004;60:1459–1472
  13. Berbeco RI, Nishioka S, Shirato H, et al. Residual motion of lung tumours in gated radiotherapy with external respiratory surrogates. Phys Med Biol. 2005;50:3655–3667
  14. Ozhasoglu C, Murphy MJ. Issues in respiratory motion compensation during external-beam radiotherapy. Int J Radiat Oncol Biol Phys. 2002;52:1389–1399
  15. Shimizu S, Shirato H, Ogura S, et al. Detection of lung tumor movement in real-time tumor-tracking radiotherapy. Int J Radiat Oncol Biol Phys. 2001;51:304–310
  16. Shirato H, Oita M, Fujita K, et al. Feasibility of synchronization of real-time tumor-tracking radiotherapy and intensity-modulated radiotherapy from viewpoint of excessive dose from fluoroscopy. Int J Radiat Oncol Biol Phys. 2004;60:335–341
  17. Seppenwoolde Y, Berbeco RI, Nishioka S, et al. Accuracy of tumor motion compensation algorithm from a robotic respiratory tracking system: A simulation study. Med Phys. 2007;34:2774–2784
  18. Murphy MJ, Balter J, Balter S, et al. The management of imaging dose during image-guided radiotherapy: Report of the AAPM Task Group 75. Med Phys. 2007;34:4041–4063
  19. Berbeco RI, Jiang SB, Sharp GC, et al. Integrated radiotherapy imaging system (IRIS): Design considerations of tumour tracking with linac gantry-mounted diagnostic x-ray systems with flat-panel detectors. Phys Med Biol. 2004;49:243–255
  20. Luo W, Yoo S, Wu J, et al. Effect of MV scatter on kV image quality during simultaneous kV-MV imaging. Int J Radiat Oncol Biol Phys. 2007;69:S671
  21. Balter JM, Wright JN, Newell LJ, et al. Accuracy of a wireless localization system for radiotherapy. Int J Radiat Oncol Biol Phys. 2005;61:933–937
  22. Santanam L, Malinowski K, Hubenshmidt J, et al. Fiducial-based translational localization accuracy of electromagnetic tracking system and on-board kilovoltage imaging system. Int J Radiat Oncol Biol Phys. 2008;70:892–899
  23. Willoughby TR, Kupelian PA, Pouliot J, et al. Target localization and real-time tracking using the Calypso 4D localization system in patients with localized prostate cancer. Int J Radiat Oncol Biol Phys. 2006;65:528–534
  24. Parikh P, Hubenschmidt J, Dimmer S, et al. 4D verification of real-time accuracy of the Calypso system with lung cancer patient trajectory data. Int J Radiat Oncol Biol Phys. 2005;63:S26–S27
  25. Malinowski K, Lechleiter K, Hubenschmidt J, et al. Use of the 4D phantom to test real-time targeted radiation therapy device accuracy. Med Phys. 2007;34:2611
  26. Low DA, Parikh PJ, Lu W, et al. Novel breathing motion model for radiotherapy. Int J Radiat Oncol Biol Phys. 2005;63:921–929
  27. Hanna G, Wang Z, Yin F. Time-delay measurement of a Varian real-time position management system. Med Phys. 2006;33:2145
  28. Jin J, Yin F. Time delay measurement for linac based treatment delivery in synchronized respiratory gating radiotherapy. Med Phys. 2005;32:1293–1296
  29. Sharp GC, Jiang SB, Shimizu S, et al. Prediction of respiratory tumour motion for real-time image-guided radiotherapy. Phys Med Biol. 2004;49:425–440
  30. Imura M, Yamazaki K, Shirato H, et al. Insertion and fixation of fiducial markers for setup and tracking of lung tumors in radiotherapy. Int J Radiat Oncol Biol Phys. 2005;63:1442–1447
  31. Whyte RI, Crownover R, Murphy MJ, et al. Stereotactic radiosurgery for lung tumors: Preliminary report of a phase I trial. Ann Thorac Surg. 2003;75:1097–1101
  32. Mayse ML, Smith RL, Park M. Development of a non-migrating electromagnetic transponder system for lung tumor tracking. Int J Radiat Oncol Biol Phys. 2008;72(Suppl.):S430

 Supported in part by Calypso Medical.

 Conflict of interest: J. Newell, B. Sargent, and J. Petersen are employees of Calypso Medical Technologies, and P. Parikh receives research funding from Calypso Medical Technologies.

PII: S0360-3016(09)00130-8

doi: 10.1016/j.ijrobp.2009.01.034

International Journal of Radiation Oncology * Biology * Physics
Volume 74, Issue 3 , Pages 920-927 , 1 July 2009