International Journal of Radiation Oncology * Biology * Physics
Volume 76, Issue 2 , Pages 361-368 , 1 February 2010

Development of RTOG Consensus Guidelines for the Definition of the Clinical Target Volume for Postoperative Conformal Radiation Therapy for Prostate Cancer

  • Jeff M. Michalski, M.D.

      Affiliations

    • Washington University School of Medicine, St. Louis, MO
    • Corresponding Author InformationReprint requests to: Jeff Michalski, M.D., Professor and Head, Department of Radiation Oncology, Washington University School of Medicine, 4921 Parkview Place, Campus box 8224, St. Louis, Missouri 63110. Tel: (314) 362-2856; Fax: (314) 747-9557
    • ,
  • Colleen Lawton, M.D.

      Affiliations

    • Medical College of Wisconsin, Milwaukee, WI
    • ,
  • Issam El Naqa, Ph.D.

      Affiliations

    • Washington University School of Medicine, St. Louis, MO
    • ,
  • Mark Ritter, M.D.

      Affiliations

    • University of Wisconsin Comprehensive Cancer Center, Madison, WI
    • ,
  • Elizabeth O'Meara, C.M.D.

      Affiliations

    • Radiation Therapy Oncology Group, Philadelphia, PA
    • ,
  • Michael J. Seider, M.D.

      Affiliations

    • Akron City Hospital, Akron, OH
    • ,
  • W. Robert Lee, M.D.

      Affiliations

    • Duke University Medical Center, Durham, NC
    • ,
  • Seth A. Rosenthal, M.D.

      Affiliations

    • Radiation Oncology Centers, Radiological Associates of Sacramento, Sacramento, CA
    • ,
  • Thomas Pisansky, M.D.

      Affiliations

    • Mayo Clinic, Rochester, MN
    • ,
  • Charles Catton, M.D.

      Affiliations

    • Princess Margaret Hospital, Toronto, Ontario, Canada
    • ,
  • Richard K. Valicenti, M.D.

      Affiliations

    • Bodine Center for Cancer Treatment, Philadelphia, PA
    • ,
  • Anthony L. Zietman, M.D.

      Affiliations

    • Massachusetts General Hospital, Boston, MA
    • ,
  • Walter R. Bosch, Ph.D.

      Affiliations

    • Washington University School of Medicine, St. Louis, MO
    • ,
  • Howard Sandler, M.D.

      Affiliations

    • University of Michigan, Ann Arbor, MI
    • ,
  • Mark K. Buyyounouski, M.D.

      Affiliations

    • Fox Chase Cancer Center, Philadelphia, PA
    • ,
  • Cynthia Ménard, M.D.

      Affiliations

    • Princess Margaret Hospital, Toronto, Ontario, Canada

Received 7 August 2008 ,Revised 29 January 2009 ,Accepted 3 February 2009.

References 

  1. Bolla M, van Poppel H, Collette L, et al. Postoperative radiotherapy after radical prostatectomy: a randomised controlled trial (EORTC trial 22911). Lancet. 2005;366:572–578
  2. Thompson IM, Tangen CM, Paradelo J, et al. Adjuvant radiotherapy for pathologically advanced prostate cancer: A randomized clinical trial. JAMA. 2006;296:2329–2335
  3. Wiegel T, Bottke D, Willich N. Phase III results of adjuvant radiotherapy (RT0 versus “wait and see” (WS) in patients with pT3 prostate cancer following radical prostatectomy (RP). ASCO. Orlando, FL; 2005.
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  13. Connolly JA, Shinohara K, Presti JC, et al. Local recurrence after radical prostatectomy: Characteristics in size, location, and relationship to prostate-specific antigen and surgical margins. Urology. 1996;47:225–231
  14. Silverman JM, Krebs TL. MR imaging evaluation with a transrectal surface coil of local recurrence of prostatic cancer in men who have undergone radical prostatectomy. AJR Am J Roentgenol. 1997;168:379–385
  15. Sella T, Schwartz LH, Swindle PW, et al. Suspected local recurrence after radical prostatectomy: endorectal coil MR imaging. Radiology. 2004;231:379–385
  16. Leventis AK, Shariat SF, Slawin KM. Local recurrence after radical prostatectomy: Correlation of US features with prostatic fossa biopsy findings. Radiology. 2001;219:432–439
  17. Miralbell R, Vees H, Lozano J, et al. Endorectal MRI assessment of local relapse after surgery for prostate cancer: A model to define treatment field guidelines for adjuvant radiotherapy in patients at high risk for local failure. Int J Radiat Oncol Biol Phys. 2007;67:356–361
  18. Poortmans P, Bossi A, Vandeputte K, et al. Guidelines for target volume definition in post-operative radiotherapy for prostate cancer, on behalf of the EORTC Radiation Oncology Group. Radiother Oncol. 2007;84:121–127
  19. Wiltshire KL, Brock KK, Haider MA, et al. Anatomic boundaries of the clinical target volume (prostate bed) after radical prostatectomy. Int J Radiat Oncol Biol Phys. 2007;69:1090–1099

 Supported by grants from the National Cancer Institute, CA21661, CA32115, and CA37422

 Conflict of interest: none.

PII: S0360-3016(09)00224-7

doi: 10.1016/j.ijrobp.2009.02.006

International Journal of Radiation Oncology * Biology * Physics
Volume 76, Issue 2 , Pages 361-368 , 1 February 2010

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