International Journal of Radiation Oncology * Biology * Physics
Volume 76, Issue 2 , Pages 460-466 , 1 February 2010

Proton Beam Therapy for Large Hepatocellular Carcinoma

  • Shinji Sugahara, M.D.

      Affiliations

    • Department of Radiation Oncology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
    • Proton Medical Research Center, University of Tsukuba, Ibaraki, Japan
    • Corresponding Author InformationReprint requests to: Shinji Sugahara, M.D., Department of Radiation Oncology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan. Tel: (+81) 298-53-3205; Fax: (+81) 298-53-3205
    • ,
  • Yoshiko Oshiro, M.D.

      Affiliations

    • Department of Radiation Oncology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
    • Proton Medical Research Center, University of Tsukuba, Ibaraki, Japan
    • ,
  • Hidetsugu Nakayama, M.D.

      Affiliations

    • Department of Radiation Oncology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
    • Proton Medical Research Center, University of Tsukuba, Ibaraki, Japan
    • ,
  • Kuniaki Fukuda, M.D.

      Affiliations

    • Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
    • ,
  • Masashi Mizumoto, M.D.

      Affiliations

    • Department of Radiation Oncology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
    • Proton Medical Research Center, University of Tsukuba, Ibaraki, Japan
    • ,
  • Masato Abei, M.D.

      Affiliations

    • Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
    • ,
  • Junichi Shoda, M.D.

      Affiliations

    • Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
    • ,
  • Yasushi Matsuzaki, M.D.

      Affiliations

    • Department of Gastroenterology, Tokyo Medical University Kasumigaura Hospital, Ibaraki, Japan
    • ,
  • Eriko Thono, M.D.

      Affiliations

    • Department of Radiology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
    • ,
  • Mari Tokita, B.A.

      Affiliations

    • Alpert Medical School of Brown University, Providence, RI
    • ,
  • Koji Tsuboi, M.D.

      Affiliations

    • Department of Radiation Oncology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
    • Proton Medical Research Center, University of Tsukuba, Ibaraki, Japan
    • ,
  • Koichi Tokuuye, M.D.

      Affiliations

    • Department of Radiation Oncology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
    • Proton Medical Research Center, University of Tsukuba, Ibaraki, Japan

Received 29 August 2008 ,Revised 6 February 2009 ,Accepted 7 February 2009.

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 S. Sugahara and Y. Oshiro contributed equally to this work.

 This study was supported in part by Grants-in-Aid for Cancer Research 15-9 and H15-006 from the Ministry of Health, Labor and Welfare of the Japanese Government.

 Conflict of interest: none.

PII: S0360-3016(09)00312-5

doi: 10.1016/j.ijrobp.2009.02.030

International Journal of Radiation Oncology * Biology * Physics
Volume 76, Issue 2 , Pages 460-466 , 1 February 2010

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