International Journal of Radiation Oncology * Biology * Physics
Volume 74, Issue 4 , Pages 987-1001 , 15 July 2009

Accelerated Partial Breast Irradiation Consensus Statement From the American Society for Radiation Oncology (ASTRO)

  • Benjamin D. Smith, M.D.

      Affiliations

    • Radiation Oncology Flight, Wilford Hall Medical Center, Lackland AFB, TX
    • Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX
    • Corresponding Author InformationReprint requests to: Benjamin D. Smith, M.D., 2200 Bergquist Drive, Suite 1, Lackland AFB, TX 78236. Tel: (210) 292-5589; Fax: (210) 292-3773
  • ,
  • Douglas W. Arthur, M.D.

      Affiliations

    • Department of Radiation Oncology, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA
  • ,
  • Thomas A. Buchholz, M.D.

      Affiliations

    • Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX
  • ,
  • Bruce G. Haffty, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Medicine and Dentistry of New Jersey – Robert Wood Johnson Medical School, New Brunswick, NJ
  • ,
  • Carol A. Hahn, M.D.

      Affiliations

    • Department of Radiation Oncology, Duke University Medical School, Durham, NC
  • ,
  • Patricia H. Hardenbergh, M.D.

      Affiliations

    • Shaw Regional Cancer Center, Veil, CO
  • ,
  • Thomas B. Julian, M.D.

      Affiliations

    • Department of Human Oncology, Allegheny General Hospital, Pittsburgh, PA
  • ,
  • Lawrence B. Marks, M.D.

      Affiliations

    • Department of Radiation Oncology, University of North Carolina Medical School, Chapel Hill, NC
  • ,
  • Dorin A. Todor, Ph.D.

      Affiliations

    • Department of Radiation Oncology, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA
  • ,
  • Frank A. Vicini, M.D.

      Affiliations

    • Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI
  • ,
  • Timothy J. Whelan, M.D.

      Affiliations

    • Department of Radiation Oncology, Juravinski Cancer Center, Hamilton, ON, Canada
  • ,
  • Julia White, M.D.

      Affiliations

    • Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI
  • ,
  • Jennifer Y. Wo, M.D.

      Affiliations

    • Harvard Radiation Oncology Residency Program, Boston, MA
  • ,
  • Jay R. Harris, M.D.

      Affiliations

    • Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital, Boston, MA

Received 4 February 2009 ,Accepted 25 February 2009.

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(A–E) Graphic comparison of ipsilateral breast tumor recurrence vs. follow-up time. Size of the circle for an individual data point is proportionate to the sample size of a given study. Thus, a larger circle indicates a larger sample size. APBI = accelerated partial-breast irradiation

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Please note that add-on components may require plug-in applications.

 Supplementary material for this article can be found at www.redjournal.org.

 This document was prepared by the Accelerated Partial Breast Irradiation Consensus Statement Task Force of the Health Services Research Committee of the American Society for Radiation Oncology (ASTRO).

 Before initiation of this Consensus Statement, all members of the Task Group writing the Statement were required to complete conflict of interest statements. These statements are maintained at ASTRO Headquarters in Fairfax, VA, and pertinent conflict information is published with the report. Individuals with disqualifying conflicts have been recused from participation in this Consensus Statement.

 ASTRO Consensus Statements present scientific, health, and safety information and may to some extent reflect scientific or medical opinion. They are made available to ASTRO members and to the public for educational and informational purposes only. Any commercial use of any content in this Statement without the prior written consent of ASTRO is strictly prohibited.

 Adherence to the guidelines set forth in this Consensus Statement will not ensure successful treatment in every situation. Furthermore, these guidelines should not be deemed inclusive of all proper methods of care or exclusive of other methods of care reasonably directed to obtaining the same results. The ultimate judgment regarding the propriety of any specific therapy must be made by the physician and the patient in light of all the circumstances presented by the individual patient. ASTRO assumes no liability for the information, conclusions, and findings contained in its consensus statements. In addition, these guidelines cannot be assumed to apply to the use of these interventions performed in the context of clinical trials, given that clinical studies are designed to evaluate or validate innovative approaches in a disease for which improved staging and treatment are needed or are being explored.

 This Consensus Statement was prepared on the basis of information available at the time the Task Group was conducting its research and discussions on the topic. There may be new developments that are not reflected in this Statement, and that may, over time, be a basis for ASTRO to consider revisiting and updating the Statement.

 Conflict of interest: D. W. Arthur, T. B. Julian, D. A. Todor, and F. A. Vicini have served as consultants to SenoRx, Irvine, CA.

PII: S0360-3016(09)00313-7

doi: 10.1016/j.ijrobp.2009.02.031

International Journal of Radiation Oncology * Biology * Physics
Volume 74, Issue 4 , Pages 987-1001 , 15 July 2009