International Journal of Radiation Oncology * Biology * Physics
Volume 74, Issue 3 , Pages 928-933, 1 July 2009

Radiation Response in Two HPV-Infected Head-and-Neck Cancer Cell Lines in Comparison to a Non–HPV-Infected Cell Line and Relationship to Signaling Through AKT

  • Anjali K. Gupta, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA
    • Corresponding Author InformationReprint requests to: Anjali K. Gupta, M.D., Department of Radiation Oncology, University of Iowa, Hospitals and Clinics, 200 Hawkins Drive, 1625 PFP LLWA, Iowa City, IA 52242. Tel: (319) 384-6135; Fax: (319) 356-1530
  • ,
  • John H. Lee, M.D.

      Affiliations

    • Sanford ENT-H&N Surgery, Sanford Cancer Research, Sioux Falls, SD
  • ,
  • Werner W. Wilke, M.D., Ph.D.

      Affiliations

    • Department of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA
  • ,
  • Harry Quon, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA
  • ,
  • Gareth Smith, B.A.

      Affiliations

    • Department of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA
  • ,
  • Amit Maity, M.D., Ph.D.

      Affiliations

    • Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA
  • ,
  • John M. Buatti, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA
  • ,
  • Douglas R. Spitz, Ph.D.

      Affiliations

    • Department of Radiation Oncology, University of Iowa Hospitals and Clinics, Iowa City, IA

Received 18 November 2008; received in revised form 10 February 2009; accepted 2 March 2009.

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 Supported by NIH grant R21 CA121580-01A1 (A.K.G.).

 Presented at 50th Annual Meeting of the American Society for Therapeutic Radiology and Oncology, Boston, MA, September 21–25, 2008.

 Anjali K. Gupta has a use patent pending on Nelfinavir as a radiation sensitizer. No other conflicts of interest to report.

PII: S0360-3016(09)00363-0

doi:10.1016/j.ijrobp.2009.03.004

International Journal of Radiation Oncology * Biology * Physics
Volume 74, Issue 3 , Pages 928-933, 1 July 2009