International Journal of Radiation Oncology * Biology * Physics
Volume 74, Issue 5 , Pages 1592-1599, 1 August 2009

B1 Sequence–Based Real-Time Quantitative PCR: A Sensitive Method for Direct Measurement of Mouse Plasma DNA Levels After Gamma Irradiation

Department of Radiation Oncology, University of Rochester School of Medicine and Dentistry, Rochester, NY

Received 12 March 2008; received in revised form 12 January 2009; accepted 8 March 2009.

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 This research was supported by the Centers for Medical Countermeasures against Radiation program, U19-AI067733, National Institute of Allergy and Infectious Diseases (NIAID).

 Conflict of interest: The authors acknowledge that a conflict of interest exists; Dr. Lurong Zhang and Dr. Paul Okunieff are co-owners of the technology development company DiaCarta, which owns intellectual property related to the measurement of radiation exposure using circulating DNA.

PII: S0360-3016(09)00427-1

doi:10.1016/j.ijrobp.2009.03.009

International Journal of Radiation Oncology * Biology * Physics
Volume 74, Issue 5 , Pages 1592-1599, 1 August 2009