International Journal of Radiation Oncology * Biology * Physics
Volume 74, Issue 4 , Pages 981-984 , 15 July 2009

Accelerated Partial Breast Irradiation: Caution and Concern From an ASTRO Task Force

  • Leonard R. Prosnitz, M.D., F.A.S.T.R.O., F.A.C.R.

      Affiliations

    • Department of Radiation Oncology, Duke University Medical Center, Durham, NC
    • Corresponding Author InformationReprint requests to: Leonard R. Prosnitz, M.D., Department of Radiation Oncology, Duke University Medical Center, Durham, NC, 27710. Tel: (919) 668-5637; Fax: (919) 668-7345
    • ,
  • Janet Horton, M.D.

      Affiliations

    • Department of Radiation Oncology, Duke University Medical Center, Durham, NC
    • ,
  • Paul E. Wallner, D.O., F.A.S.T.R.O., F.A.C.R., F.A.O.C.R., F.A.C.R.O.

      Affiliations

    • 21st Century Oncology, Moorestown, NJ

Received 31 March 2009 ,Accepted 31 March 2009.

References 

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  2. Arthur DW, Vicini FA. Accelerated partial breast irradiation as a part of breast conservation therapy. J Clin Oncol. 2005;23:1726–1735
  3. Houssami N, Ciatto S, Macaskill P, et al. Accuracy and surgical impact of magnetic resonance imaging in breast cancer staging: Systematic review and meta-analysis in detection of multifocal and multicentric cancer. J Clin Oncol. 2008;26:3248–3258
  4. Al-Hallaq HA, Mell LK, Bradley JA, et al. Magnetic resonance imaging identifies multifocal and multicentric disease in breast cancer patients who are eligible for partial breast irradiation. Cancer. 2008;113:2408–2414
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  7. Whelan TJ, Pignol J, Julian J, et al. Long-term results of a randomized trial of accelerated hypofractionated whole breast irradiation following breast conserving surgery in women with node-negative breast cancer. Int J Radiat Oncol Biol Phys. 2008;72:S28
  8. Bentzen SM, Agrawal RK, Aird EG, et al. The UK Standardisation of Breast Radiotherapy (START) Trial A of radiotherapy hypofractionation for treatment of early breast cancer: A randomised trial. Lancet Oncol. 2008;9:331–341
  9. Bentzen SM, Agrawal RK, Aird EG, et al. The UK Standardisation of Breast Radiotherapy (START) Trial B of radiotherapy hypofractionation for treatment of early breast cancer: A randomised trial. Lancet. 2008;371:1098–1107
  10. Yarnold J, Ashton A, Bliss J, et al. Fractionation sensitivity and dose response of late adverse effects in the breast after radiotherapy for early breast cancer: Long-term results of a randomised trial. Radiother Oncol. 2005;75:9–17
  11. Favourable and unfavourable effects on long-term survival of radiotherapy for early breast cancer: An overview of the randomised trials. Early Breast Cancer Trialists' Collaborative Group. Lancet. 2000;355:1757–1770
  12. Holli K, Hietanen P, Saaristo R, et al. Radiotherapy after segmental resection of breast cancer with favorable prognostic features: 12-year follow-up results of a randomized trial. J Clin Oncol. 2009;27:927–932
  13. Hughes KS, Schnaper LA, Berry D, et al. Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer. N Engl J Med. 2004;351:971–977
  14. Veronesi U, Marubini E, Mariani L, et al. Radiotherapy after breast-conserving surgery in small breast carcinoma: Long-term results of a randomized trial. Ann Oncol. 2001;12:997–1003

 Conflict of interest: none.

PII: S0360-3016(09)00508-2

doi: 10.1016/j.ijrobp.2009.03.046

International Journal of Radiation Oncology * Biology * Physics
Volume 74, Issue 4 , Pages 981-984 , 15 July 2009

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