International Journal of Radiation Oncology * Biology * Physics
Volume 76, Issue 5 , Pages 1333-1338 , April 2010

Multi-Institutional Trial of Accelerated Hypofractionated Intensity-Modulated Radiation Therapy for Early-Stage Oropharyngeal Cancer (RTOG 00-22)

  • Avraham Eisbruch, M.D.

      Affiliations

    • University of Michigan, Ann Arbor, MI
    • Corresponding Author InformationReprint requests to: Avraham Eisbruch, M.D., Department of Radiation Oncology, University of Michigan Hospital, 1500 E. Medical Center Drive, Ann Arbor, MI 48109. Tel: (734) 936-9337; Fax: (734) 936-4300
    • ,
  • Jonathan Harris, M.S.

      Affiliations

    • Department of Statistics, American College of Radiology
    • ,
  • Adam S. Garden, M.D.

      Affiliations

    • M.D. Anderson Cancer Center, Houston, TX
    • ,
  • Clifford K.S. Chao, M.D.

      Affiliations

    • M.D. Anderson Cancer Center, Houston, TX
    • ,
  • William Straube, Ph.D.

      Affiliations

    • Image-Guided Therapy Center at Washington University, St. Louis, MO
    • ,
  • Paul M. Harari, M.D.

      Affiliations

    • University of Wisconsin, Madison, WI
    • ,
  • Giuseppe Sanguineti, M.D.

      Affiliations

    • University of Texas Medical Branch, Galveston, TX
    • ,
  • Christopher U. Jones, M.D.

      Affiliations

    • Radiation Oncology Center, Sacramento, CA
    • ,
  • Walter R. Bosch, D.Sc.

      Affiliations

    • Image-Guided Therapy Center at Washington University, St. Louis, MO
    • ,
  • K. Kian Ang, M.D., Ph.D.

      Affiliations

    • M.D. Anderson Cancer Center, Houston, TX

Received 18 February 2009 ,Revised 3 April 2009 ,Accepted 7 April 2009.

References 

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  3. Eisbruch A, Marsh LH, Dawson LA, et al. Recurrences near base of skull after IMRT for head-and-neck cancer: Implications for target delineation in high neck and for parotid gland sparing. Int J Radiat Oncol Biol Phys. 2004;59:28–42
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  18. Lauve A, Morris M, Schmidt-Ullrich R, et al. Simultaneous integrated boost IMRT for head-and-neck carcinomas: II—clinical results. Int J Radiat Oncol Biol Phys. 2004;60:374–387
  19. Eisbruch A, Gregoire V. Balancing risk and reward in target delineation for highly conformal radiotherapy in head and neck cancer. Semin Radiat Oncol. 2009;19:43–52
  20. Amosson CM, The BS, Garg AK, et al. Accelerated fractionation for head and neck cancer using SMART boost. Int J Radiat Oncol Biol Phys. 2003;57:S306;[abstract 1076]
  21. Ben David MA, Diamante M, Radawski JD, et al. Lack of osteoradionecrosis of the mandible after IMRT for head and neck cancer. Int J Radiat Oncol Biol Phys. 2007;68:396–402
  22. Eisbruch A, Kim HM, Terrell JE, et al. Xerostomia and its predictors following parotid-sparing irradiation of head and neck cancer. Int J Radiat Oncol Biol Phys. 2001;50:695–704
  23. Kam MMK, Leung SF, Zee B, et al. Impact of IMRT on salivary function in nasopharyngeal carcinoma. J Clin Oncol. 2007;25:4873–4879

 Supported by NCI grants ATC U24 CA81647, RTOG U10 CA21661, CCOP U10 CA37422.

 Conflict of interest: none.

PII: S0360-3016(09)00558-6

doi: 10.1016/j.ijrobp.2009.04.011

International Journal of Radiation Oncology * Biology * Physics
Volume 76, Issue 5 , Pages 1333-1338 , April 2010

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