International Journal of Radiation Oncology * Biology * Physics
Volume 75, Issue 1 , Pages 212-219 , 1 September 2009

Radiosensitizing Effects of Temozolomide Observed in vivo only in a Subset of O6-Methylguanine-DNA Methyltransferase Methylated Glioblastoma Multiforme Xenografts

  • Brett L. Carlson, B.S.

      Affiliations

    • Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Patrick T. Grogan, B.S.

      Affiliations

    • Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Ann C. Mladek, B.S.

      Affiliations

    • Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Mark A. Schroeder

      Affiliations

    • Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Gaspar J. Kitange, M.D., Ph.D.

      Affiliations

    • Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Paul A. Decker, M.S.

      Affiliations

    • Department of Biostatistics, Mayo Clinic, Rochester, Minnesota
    • ,
  • Caterina Giannini, M.D.

      Affiliations

    • Department of Pathology, Mayo Clinic, Rochester, Minnesota
    • ,
  • Wenting Wu, Ph.D.

      Affiliations

    • Department of Biostatistics, Mayo Clinic, Rochester, Minnesota
    • ,
  • Karla A. Ballman, Ph.D.

      Affiliations

    • Department of Biostatistics, Mayo Clinic, Rochester, Minnesota
    • ,
  • C. David James, Ph.D.

      Affiliations

    • Department of Neurological Surgery and Brain Tumor Research Center, University of California San Francisco, San Francisco, California
    • ,
  • Jann N. Sarkaria, M.D.

      Affiliations

    • Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota
    • Corresponding Author InformationReprint requests to: Jann Sarkaria, M.D., Mayo Clinic, 200 First St. SW, Rochester, MN 55905. Tel.: (507) 266-3877; Fax: (507) 284-0079

Received 16 March 2009 ,Revised 20 April 2009 ,Accepted 22 April 2009.

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 This work was supported by the Mayo Foundation, the National Cancer Institute (CA108961 and CA127716), and the Brain Tumor Funders Consortium.

 Conflict of interest: none.

PII: S0360-3016(09)00603-8

doi: 10.1016/j.ijrobp.2009.04.026

International Journal of Radiation Oncology * Biology * Physics
Volume 75, Issue 1 , Pages 212-219 , 1 September 2009

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