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International Journal of Radiation Oncology * Biology * Physics
Volume 77, Issue 3
, Pages 699-706
, 1 July 2010
PET CT Thresholds for Radiotherapy Target Definition in Non–Small-Cell Lung Cancer: How Close Are We to the Pathologic Findings?
References
- Gross tumor volume, critical prognostic factor in patients treated with three-dimensional conformal radiation therapy for non–small-cell lung carcinoma. Int J Radiat Oncol Biol Phys. 2002;52:49–57
- Dose, volume, and tumor control prediction in primary radiotherapy of non–small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2002;52:382–389
- Improved local control with higher doses of radiation in large-volume stage III non–small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2004;60:741–747
- High-dose radiation improved local tumor control and overall survival in patients with inoperable/unresectable non–small-cell lung cancer: long-term results of a radiation dose escalation study. Int J Radiat Oncol Biol Phys. 2005;63:324–333
- (18)F-FDG PET provides high-impact and powerful prognostic stratification in staging newly diagnosed non-small cell lung cancer. J Nucl Med. 2001;42:1596–1604
- A tabulated summary of the FDG PET literature. J Nucl Med. 2001;42:1S–93S
- The usefulness of FDG positron emission tomography for the detection of mediastinal lymph node metastases in patients with non-small cell lung cancer: A comparative study with X-ray computed tomography. Eur J Nucl Med. 1996;23:741–747
- The influence of plasma glucose levels on fluorine-18-fluorodeoxyglucose uptake in bronchial carcinomas. J Nucl Med. 1993;34:355–359
- Defining a radiotherapy target with positron emission tomography. Int J Radiat Oncol Biol Phys. 2004;60:1272–1282
- Radiotherapy treatment planning for patients with non-small cell lung cancer using positron emission tomography (PET). Radiother Oncol. 2002;62:51–60
- The contribution of integrated PET/CT to the evolving definition of treatment volumes in radiation treatment planning in lung cancer. Int J Radiat Oncol Biol Phys. 2005;63:1016–1023
- The impact of (18)FDG-PET on target and critical organs in CT-based treatment planning of patients with poorly defined non–small-cell lung carcinoma: A prospective study. Int J Radiat Oncol Biol Phys. 2002;52:339–350
- Radiation treatment planning with an integrated positron emission and computer tomography (PET/CT): A feasibility study. Int J Radiat Oncol Biol Phys. 2003;57:853–863
- Increased therapeutic ratio by 18FDG-PET CT planning in patients with clinical CT stage N2-N3M0 non–small-cell lung cancer: A modeling study. Int J Radiat Oncol Biol Phys. 2005;61:649–655
- Clinical impact of (18)F fluorodeoxyglucose positron emission tomography in patients with non–small-cell lung cancer: A prospective study. J Clin Oncol. 2001;19:111–118
- Evaluation of microscopic tumor extension in non–small-cell lung cancer for three-dimensional conformal radiotherapy planning. Int J Radiat Oncol Biol Phys. 2000;48:1015–1024
- Computed tomographic-pathologic correlation of gross tumor volume and clinical target volume in non-small cell lung cancer: A pilot experience. Arch Pathol Lab Med. 2001;125:1469–1472
- Feasibility of pathology-correlated lung imaging for accurate target definition of lung tumors. Int J Radiat Oncol Biol Phys. 2007;69:267–275
- Non–small-cell lung cancer dimensions: CT-pathological correlation and interobserver variation. Br J Radiol. 2009;82:421–425
- Lung tumor growth correlates with glucose metabolism measured by fluoride-18 fluorodeoxyglucose positron emission tomography. Ann Thorac Surg. 1995;60:1348–1352
- . Probability of malignancy in solitary pulmonary nodules using fluorine-18-FDG and PET. J Nucl Med. 1996;37:943–948
- FDG SPECT in patients with lung masses. Chest. 1999;115:1012–1017
- FDG positron emission tomography in the diagnosis of peripheral pulmonary focal lesions. Thorac Cardiovasc Surg. 2000;48:97–101
- 18Fluorodeoxyglucose positron emission tomography in the diagnosis and staging of lung cancer: A systematic review. J Natl Cancer Inst. 2007;99:1753–1767
- . Molecular imaging to improve radiotherapy. Radiother Oncol. 2006;78:233–235
- Impact of FDG-PET on radiation therapy volume delineation in non–small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2004;59:78–86
- The contribution of 18F-fluoro-2-deoxy-glucose positron emission tomographic imaging to radiotherapy planning in lung cancer. Lung Cancer. 1998;19:167–177
- Observer variation in contouring gross tumor volume in patients with poorly defined non–small-cell lung tumors on CT: The impact of 18FDG-hybrid PET fusion. Int J Radiat Oncol Biol Phys. 2001;51:923–931
- Segmentation of lung lesion volume by adaptive positron emission tomography image thresholding. Cancer. 1997;80:2505–2509
- Comparison of different methods for delineation of 18F-FDG PET-positive tissue for target volume definition in radiotherapy of patients with non-small cell lung cancer. J Nucl Med. 2005;46:1342–1348
- . Practical integration of [18F]-FDG-PET and PET-CT in the planning of radiotherapy for non-small cell lung cancer (NSCLC): The technical basis, ICRU-target volumes, problems, perspectives. Radiother Oncol. 2006;81:209–225
- . 18F-FDG PET in planning radiation treatment of non-small cell lung cancer: Where exactly is the tumor?. J Nucl Med. 2007;48:1402
- Whole-specimen histopathology: A method to produce whole-mount breast serial sections for 3-D digital histopathology imaging. Histopathology. 2007;50:232–342
- Developing a methodology for three-dimensional correlation of PET-CT images and whole-mount histopathology in non–small-cell lung cancer. Current Oncology. 2008;15:62–69
- Inter-observer variability in the delineation of pharyngo-laryngeal tumor, parotid glands and cervical spinal cord: Comparison between CT-scan and MRI. Radiother Oncol. 2005;77:25–31
- PET-CT-based auto-contouring in non–small-cell lung cancer correlates with pathology and reduces interobserver variability in the delineation of the primary tumor and involved nodal volumes. Int J Radiat Oncol Biol Phys. 2007;68:771–778
- Observer variation in target volume delineation of lung cancer related to radiation oncologist-computer interaction: A “big brother” evaluation. Radiother Oncol. 2005;77:182–190
- Can PET provide the 3D extent of tumor motion for individualized internal target volumes? A phantom study of the limitations of CT and the promise of PET. Int J Radiat Oncol Biol Phys. 2003;55:1381–1393
- Distribution of stage I lung cancer growth rates determined with serial volumetric CT measurements. Radiology. 2006;241:554–563
Supported by the Ontario Cancer Research Network (OCRN) and Ontario Clinical Oncology Group (OCOG).
Conflict of interest: none.
PII: S0360-3016(09)00791-3
doi: 10.1016/j.ijrobp.2009.05.028
© 2010 Elsevier Inc. All rights reserved.
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International Journal of Radiation Oncology * Biology * Physics
Volume 77, Issue 3
, Pages 699-706
, 1 July 2010
