International Journal of Radiation Oncology * Biology * Physics
Volume 78, Issue 3 , Pages 849-854 , 1 November 2010

Whole Neuraxis Irradiation to Address Central Nervous System Relapse in High-Risk Neuroblastoma

These data were presented as an abstract and poster at the American Society of Clinical Oncology 2008 Annual Meeting in Chicago, IL, June 2008.

  • Victoria J. Croog, M.D.

      Affiliations

    • Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY
    • Corresponding Author InformationReprint requests to: Victoria J. Croog, M.D., Sibley Memorial Hospital, Department of Radiation Oncology, 5255 Loughboro Road NW, Washington, D.C. 20016. Tel: (202) 537-4787
    • ,
  • Kim Kramer, M.D.

      Affiliations

    • Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY
    • ,
  • Nai-Kong V. Cheung, M.D., Ph.D.

      Affiliations

    • Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY
    • ,
  • Brian H. Kushner, M.D.

      Affiliations

    • Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY
    • ,
  • Shakeel Modak, M.D.

      Affiliations

    • Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY
    • ,
  • Mark M. Souweidane, M.D.

      Affiliations

    • Department of Neurosurgery, Memorial Sloan-Kettering Cancer Center, New York, NY
    • ,
  • Suzanne L. Wolden, M.D.

      Affiliations

    • Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY

Received 27 August 2008 ,Revised 31 August 2009 ,Accepted 2 September 2009.

References 

  1. Kramer K, Kushner B, Heller G, et al. Neuroblastoma metastatic to the central nervous system. Cancer. 2001;91:1510–1519
  2. Kellie SJ, Hayes FA, Bowman L, et al. Primary extracranial neuroblastoma with central nervous system metastases characterization by clinicopathologic findings and neuroimaging. Cancer. 1991;68:1999–2006
  3. Matthay K, Brisse H, Couanet D, et al. Central nervous system metastases in neuroblastoma. Cancer. 2003;98:155–165
  4. Palasis S, Morris J, Egelhoff JC. Central nervous system relapse after bone marrow transplantation in Stage IV neuroblastoma. Pediatr Hematol Oncol. 1999;16:443–452
  5. Paulino AC, Nguyen TX, Barker JL. Brain metastasis in children with sarcoma, neuroblastoma, and Wilms' tumor. Int J Radiat Oncol Biol Phys. 2003;57:177–183
  6. Astigarraga I, Lejarreta R, Navajas A, et al. Secondary central nervous system metastases in children with neuroblastoma. Med Pediatr Oncol. 1996;27:529–533
  7. Blatt J, Fitz C, Mirro J. Recognition of central nervous system metastases in children with metastatic primary extracranial neuroblastoma. Pediatr Hematol Oncol. 1997;14:233–241
  8. Shaw PJ, Eden T. Neuroblastoma with intracranial involvement: An ENSG Study. Med Pediatr Oncol. 1992;20:149–155
  9. Porto L, Kieslich M, Yan B, et al. Isolated CNS relapse in neuroblastoma. Neuropediatrics. 2005;36:112–116
  10. Kramer K, Humm JL, Souweidane MM, et al. Phase I study of targeted radioimmunotherapy for leptomeningeal cancers using intra-Ommaya 131-I-3F8. J Clin Oncol. 2007;25:5465–5470
  11. Modak S, Cheung N-KV. Disialoganglioside directed immunotherapy of neuroblastoma. Cancer Invest. 2007;25:67–77
  12. Bouffet E, Doumi N, Thiesse P, et al. Brain metastases in children with solid tumors. Cancer. 1997;79:403–410
  13. Cheung NK, Kushner BH, Cheung IY, et al. Anti-G(D2) antibody treatment of minimal residual Stage 4 neuroblastoma diagnosed at more than 1 year of age. J Clin Oncol. 1998;16:3053–3060
  14. Kushner BH, Kramer K, Cheung NK. Phase II trial of the anti-G(D2) monoclonal antibody 3F8 and granulocyte-macrophage colony-stimulating factor for neuroblastoma. J Clin Oncol. 2001;19:4189–4194
  15. Modak S, Kramer K, Gultekin SH, et al. Monoclonal antibody 8H9 targets a novel cell surface antigen expressed by a wide spectrum of human solid tumors. Cancer Res. 2001;61:4048–4054
  16. Onda M, Wang Q-c, Guo H-f, et al. In vitro and in vivo cytotoxic activities of recombinant immunotoxin 8H9(Fv)-PE38 against breast cancer, osteosarcoma, and neuroblastoma. Cancer Res. 2004;64:1419–1424
  17. de la Monte SM, Moore GW, Hutchins GM. Nonrandom distribution of metastases in neuroblastic tumors. Cancer. 1983;52:915–925
  18. Frappaz D, Bouffet E, Thiesse P, et al. Isolated intraspinal relapse of neuroblastoma after autologous bone marrow transplantation. Pediatr Hematol Oncol. 1994;11:439–443
  19. Koizumi JH, Dal Canto MC. Retroperitoneal neuroblastoma metastatic to brain. Report of a case and review of the literature. Child Brain. 1980;7:267–279
  20. Sawada T, Matsumura T, Esumi N, et al. Intraspinal metastasis of neuroblastoma—report of a case detected at autopsy. Jpn J Clin Oncol. 1983;13:719–726
  21. Xaidara A, Andrioti M, Mikraki V, et al. Neuroblastoma metastatic to brain. Med Pediatr Oncol. 1996;26:208–214
  22. DuBois SG, Kalika Y, Lukens JN, et al. Metastatic sites in Stage IV and IVS neuroblastoma correlate with age, tumor biology, and survival. J Pediatr Hematol Oncol. 1999;21:181–189

 Conflict of interest: none.

PII: S0360-3016(09)03107-1

doi: 10.1016/j.ijrobp.2009.09.005

International Journal of Radiation Oncology * Biology * Physics
Volume 78, Issue 3 , Pages 849-854 , 1 November 2010

Article Tools