International Journal of Radiation Oncology * Biology * Physics
Volume 78, Issue 4 , Pages 1005-1010 , 15 November 2010

Intensity-Modulated Radiotherapy for Cervical Node Squamous Cell Carcinoma Metastases From Unknown Head-and-Neck Primary Site: M. D. Anderson Cancer Center Outcomes and Patterns of Failure

  • Steven J. Frank, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX
    • Corresponding Author InformationReprint requests to: Steven J. Frank, M.D., Division of Radiation Oncology, Unit 97, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030. Tel: (713) 563-8489; Fax: (713) 563-2366
    • ,
  • David I. Rosenthal, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX
    • ,
  • Janjira Petsuksiri, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX
    • ,
  • K. Kian Ang, M.D., Ph.D.

      Affiliations

    • Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX
    • ,
  • William H. Morrison, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX
    • ,
  • Randal S. Weber, M.D.

      Affiliations

    • Department of Head and Neck Surgery, University of Texas M. D. Anderson Cancer Center, Houston, TX
    • ,
  • Bonnie S. Glisson, M.D.

      Affiliations

    • Department of Thoracic /Head and Neck Medical Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX
    • ,
  • K.S. Clifford Chao, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX
    • ,
  • David L. Schwartz, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX
    • ,
  • Gregory M. Chronowski, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX
    • ,
  • Adel K. El-Naggar, M.D., Ph.D.

      Affiliations

    • Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston, TX
    • ,
  • Adam S. Garden, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, TX

Received 24 June 2009 ,Revised 14 August 2009 ,Accepted 9 September 2009.

References 

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  17. Kam MKM, Leung SF, Zee B, et al. Prospective randomized study of intensity-modulated radiotherapy on salivary gland function in early-stage nasopharyngeal carcinoma patients. J Clin Oncol. 2007;31:4873–4879
  18. Frank SJ, Chao KS, Schwartz DL, et al. Technology insight: PET and PET/CT in head and neck tumor staging and radiation therapy planning. Nat Clin Pract Oncol. 2005;2:526–533
  19. Bernier J, Cooper JS, Pajak TF, et al. Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (#9501). Head Neck. 2005;27:843–850
  20. Lindel K, Beer KT, Laissue J, et al. Human papillomavirus positive squamous cell carcinoma of the oropharynx: A radiosensitive subgroup of head and neck carcinomas. Cancer. 2001;92:805–813
  21. Hafkamp HC, Manni JJ, Haesevoets A, et al. Marked differences in survival rate between smokers and nonsmokers with HPV 16-associated tonsillar carcinomas. Int J Cancer. 2008;122:2656–2664
  22. Mendenhall WM, Mancuso AA, Amdur RJ, et al. Squamous cell carcinoma metastatic to the neck from an unknown head and neck primary site. Am J Otolaryngol. 2001;22:261–267
  23. Amdur RJ, Li JG, Liu C, et al. Unnecessary laryngeal irradiation in the IMRT era. Head Neck. 2004;26:257–263

 Conflict of interest: none.

PII: S0360-3016(09)03108-3

doi: 10.1016/j.ijrobp.2009.09.006

International Journal of Radiation Oncology * Biology * Physics
Volume 78, Issue 4 , Pages 1005-1010 , 15 November 2010

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