International Journal of Radiation Oncology * Biology * Physics
Volume 79, Issue 5 , Pages 1358-1363 , 1 April 2011

Acupuncture for the Alleviation of Hot Flashes in Men Treated With Androgen Ablation Therapy

Presented in part at the American Society of Clinical Oncologists meeting Chicago, IL 2008.

  • Hani Ashamalla, M.D., F.C.C.P.

      Affiliations

    • Radiation Oncology Department, Weill Medical College of Cornell University, Brooklyn, NY
    • Corresponding Author InformationReprint requests to: Hani Ashamalla, M.D., F.C.C.P., New York Methodist Hospital, Department of Radiation Oncology 506 Sixth Street, Brooklyn, NY 11215. Tel: (718) 780-3677; Fax: (718) 780-3688
    • ,
  • Ming L. Jiang, M.D.

      Affiliations

    • Acupuncture Section of New York Methodist Hospital, Weill Medical College of Cornell University, Brooklyn, NY
    • ,
  • Adel Guirguis, M.B.B.C.H., M.S.

      Affiliations

    • Radiation Oncology Department, Weill Medical College of Cornell University, Brooklyn, NY
    • ,
  • Francesco Peluso, B.A.

      Affiliations

    • Radiation Oncology Department, Weill Medical College of Cornell University, Brooklyn, NY
    • ,
  • Mark Ashamalla, B.A.

      Affiliations

    • Radiation Oncology Department, Weill Medical College of Cornell University, Brooklyn, NY

Received 10 November 2009 ,Revised 15 December 2009 ,Accepted 6 January 2010.

References 

  1. Casper RF, Yen SSC. Neuroendocrinology of menopausal flushes: An hypothesis of flush mechanism. Clin Endocrinol. 1985;22:293–312
  2. Kronenberg F. Menopausal hot flashes: Randomness or rhythmicity. Chaos. 1991;1:271–278
  3. Spetz AC, Zetterlund EL, Varenhorst E, et al. Incidence and management of hot flashes in prostate cancer. J Support Oncol. 2003;1:263–266
  4. Loprinzi CL, Sloan J, Stearns V, et al. Newer antidepressants and gabapentin for hot flashes: An individual patient pooled analysis. J Clin Oncol. 2009;16:883–887
  5. Quella SK, Loprinzi CL, Sloan JA, et al. Pilot evaluation of venlafaxine for the treatment of hot flashes in men undergoing androgen ablation therapy for prostate cancer. J Clin Oncol. 1998;16:2377–2381
  6. Loprinzi C, Dueck AC, Khoyratty BS, et al. A Phase III randomized, double-blind, placebo-controlled trial of gabapentin in the management of hot flashes in men. Ann Oncol. 2009;20:542–549
  7. Nelson H, Vesco K, Haney E, et al. Nonhormonal therapies for menopausal hot flashes: Systematic review and meta-analysis. JAMA. 2006;295:2057–2071
  8. Lin JG, Chen WL. Acupuncture analgesia: A review of its mechanisms of actions. Am J Chin Med. 2008;36:635–645
  9. Han SJ. Acupuncture and endorphins. Neurosci Lett. 2004;361:258
  10. Shanafelt T, Barton D, Adjei A, et al. Pathophysiology and treatment of hot flashes. Mayo Clinic Proc. 2002;77:1207–1218
  11. Berendsen H. The role of serotonin in hot flushes. Maturitas. 2000;36:155–164
  12. Frisk J, Spetz AC, Hjertberg H, et al. Two modes of acupuncture as a treatment for hot flushes in men with prostate cancer—a prospective multicenter study with long term follow-up. Eur Urol. 2009;55:156–163
  13. Hammar M, Frisk J, Grimas O, et al. Acupuncture treatment of vasomotor symptoms in men with prostatic carcinoma: A pilot study. J Urol. 1999;161:853–856
  14. Hayes M, Katovic NM, Donovan D, et al. Acupuncture for hot flashes in prostate cancer patients. [Abstract] J Clin Oncol. 2005;23(Suppl. 16):8160
  15. Oken MM, Creech RH, Tormey DC, et al. Toxicity and response criteria of the eastern cooperative oncology group. Am J Clin Oncol. 1982;5:649–655
  16. STATA Corp. Stata Statistical Software. Release 10. College Station, TX: StataCorp; 2007;
  17. Sloan JA, Loprinzi CL, Novotny PJ, et al. Methodologic lessons learned from hot flash studies. J Clin Oncol. 2001;19:4280–4290
  18. Higano CS. Side effects of androgen deprivation therapy: Monitoring and minimizing toxicity. Urology. 2003;61(Suppl. 2A):32
  19. Loprinzi CL, Barton DL, Sloan JA, et al. Mayo Clinic and North Central Cancer Treatment Group hot flash studies: A 20-year experience. Menopause. 2008;15:655–660
  20. Loprinzi CL, Barton DL, Carpenter LA, et al. Pilot evaluation of paroxetine for treating hot flashes in men. Mayo Clinic. 2004;79:1247–1251

 Conflict of interest: none.

PII: S0360-3016(10)00124-0

doi: 10.1016/j.ijrobp.2010.01.025

International Journal of Radiation Oncology * Biology * Physics
Volume 79, Issue 5 , Pages 1358-1363 , 1 April 2011

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