International Journal of Radiation Oncology * Biology * Physics
Volume 78, Issue 5 , Pages 1494-1502 , 1 December 2010

Melanin-Covered Nanoparticles for Protection of Bone Marrow During Radiation Therapy of Cancer

  • Andrew D. Schweitzer, M.D.

      Affiliations

    • Department of Nuclear Medicine, Albert Einstein College of Medicine, Bronx, NY
    • Howard Hughes Medical Institute–Medical Fellows Program, Chevy Chase, MD
    • The Mount Sinai School of Medicine, New York, NY
  • ,
  • Ekaterina Revskaya, Ph.D.

      Affiliations

    • Department of Nuclear Medicine, Albert Einstein College of Medicine, Bronx, NY
  • ,
  • Peter Chu, B.Sc.

      Affiliations

    • Department of Nuclear Medicine, Albert Einstein College of Medicine, Bronx, NY
  • ,
  • Valeria Pazo, M.D.

      Affiliations

    • Jacobi Medical Center, Bronx, NY
  • ,
  • Matthew Friedman

      Affiliations

    • Department of Nuclear Medicine, Albert Einstein College of Medicine, Bronx, NY
  • ,
  • Joshua D. Nosanchuk, M.D.

      Affiliations

    • Department of Medicine, Albert Einstein College of Medicine, Bronx, NY
    • Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY
  • ,
  • Sean Cahill, Ph.D.

      Affiliations

    • Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY
  • ,
  • Susana Frases, Ph.D.

      Affiliations

    • Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY
  • ,
  • Arturo Casadevall, M.D., Ph.D.

      Affiliations

    • Department of Medicine, Albert Einstein College of Medicine, Bronx, NY
    • Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY
  • ,
  • Ekaterina Dadachova, Ph.D.

      Affiliations

    • Department of Nuclear Medicine, Albert Einstein College of Medicine, Bronx, NY
    • Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY
    • Corresponding Author InformationReprint requests to: Ekaterina Dadachova, Ph.D., Department of Nuclear Medicine, Albert Einstein College of Medicine, 1695A Eastchester Rd., Bronx, NY 10461. Tel: (718) 405-8485; Fax: (718) 405-8457

Received 28 September 2009 ,Revised 15 December 2009 ,Accepted 12 February 2010.

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 A. D. Schweitzer, E. Revskaya, and P. Chu contributed equally to this study.

 A. D. Schweitzer was a Howard Hughes Medical Institute Medical Research Training Fellow. A. Casadevall and J. D. Nosanchuk were supported by National Institutes of Health award AI052733. The instrumentation in the Albert Einstein College of Medicine Structural NMR (Nuclear Magnetic Resonance) Resource is supported by the Albert Einstein College of Medicine and in part by grants from the National Science Foundation (DBI9601607 and DBI0331934), the National Institutes of Health (RR017998), and the Howard Hughes Medical Institute Research Resources for Biomedical Sciences.

 Conflict of interest: none.

PII: S0360-3016(10)00254-3

doi: 10.1016/j.ijrobp.2010.02.020

International Journal of Radiation Oncology * Biology * Physics
Volume 78, Issue 5 , Pages 1494-1502 , 1 December 2010