International Journal of Radiation Oncology * Biology * Physics
Volume 82, Issue 3 , Pages 1065-1074 , 1 March 2012

Standardized Total Average Toxicity Score: A Scale- and Grade-Independent Measure of Late Radiotherapy Toxicity to Facilitate Pooling of Data From Different Studies

  • Gillian C. Barnett, B.M., B.Ch.

      Affiliations

    • University of Cambridge Department of Oncology, Oncology Centre, Cambridge, UK
    • Cancer Research-UK Centre for Genetic Epidemiology & Department of Oncology, Strangeways Research Laboratories, Cambridge, UK
    • Corresponding Author InformationReprint requests to: Dr Gillian C. Barnett, B.M., B.Ch., Department of Oncology, Strangeways Research Laboratories, Wort’s Causeway, Cambridge, CB1 8RN, UK. Tel: (0)1223 741168; Fax: (0)1223 740147
    • ,
  • Catharine M.L. West, Ph.D.

      Affiliations

    • School of Cancer & Enabling Sciences, Manchester Academic Health Science Centre, University of Manchester, Christie Hospital, Manchester, UK
    • ,
  • Charlotte E. Coles, Ph.D.

      Affiliations

    • University of Cambridge Department of Oncology, Oncology Centre, Cambridge, UK
    • ,
  • Paul D.P. Pharoah, Ph.D.

      Affiliations

    • Cancer Research-UK Centre for Genetic Epidemiology & Department of Oncology, Strangeways Research Laboratories, Cambridge, UK
    • ,
  • Christopher J. Talbot, Ph.D.

      Affiliations

    • Department of Genetics, University of Leicester, Leicester, UK
    • ,
  • Rebecca M. Elliott, M.Res.

      Affiliations

    • School of Cancer & Enabling Sciences, Manchester Academic Health Science Centre, University of Manchester, Christie Hospital, Manchester, UK
    • ,
  • George A. Tanteles, M.D.

      Affiliations

    • Department of Clinical Genetics, University Hospitals of Leicester, Leicester, UK
    • ,
  • R. Paul Symonds, M.D.

      Affiliations

    • Department of Cancer Studies and Molecular Medicine, University Hospitals of Leicester, Leicester, UK
    • ,
  • Jennifer S. Wilkinson, B.Sc.

      Affiliations

    • University of Cambridge Department of Oncology, Oncology Centre, Cambridge, UK
    • ,
  • Alison M. Dunning, Ph.D.

      Affiliations

    • Cancer Research-UK Centre for Genetic Epidemiology & Department of Oncology, Strangeways Research Laboratories, Cambridge, UK
    • ,
  • Neil G. Burnet, M.D.

      Affiliations

    • University of Cambridge Department of Oncology, Oncology Centre, Cambridge, UK
    • ,
  • Søren M. Bentzen, Ph.D.

      Affiliations

    • University of Wisconsin, School of Medicine and Public Health, Department of Human Oncology, Madison, WI

Received 18 November 2010 ,Revised 15 March 2011 ,Accepted 18 March 2011.

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 Supported by the Royal College of Radiologists, Cancer Research UK, Addenbrooke’s Charitable Trust, Breast Cancer Campaign, Cambridge National Institute of Health Research Biomedical Research Centre, Experimental Cancer Medicine Centre, the National Cancer Institute, and East Midlands Innovation.

 Conflict of interest: none.

PII: S0360-3016(11)00473-1

doi: 10.1016/j.ijrobp.2011.03.015

International Journal of Radiation Oncology * Biology * Physics
Volume 82, Issue 3 , Pages 1065-1074 , 1 March 2012

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