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Issue Highlights page A25 Full Text | Full-Text PDF (28 KB)
Editorial
How Best To Dispose of Extra-Tumoral Dose: A Cautionary Note for Intensity-Modulated Radiation Therapy Michael Goitein pages 1-3 Full Text | Full-Text PDF (66 KB)
Controversy
Commissioning and Quality Assurance of RapidArc Radiotherapy Delivery System: In Regard to Ling et al. (Int J Radiat Oncol Biol Phys 2008;72;575–581): Absence of Data Does Not Constitute Proof; The Proof is in Tasting the Pudding Minesh Mehta, Peter Hoban, T. Rock Mackie pages 4-6 Full Text | Full-Text PDF (86 KB)
Dueling Technologies: In regard to Ling et al. (Int J Radiat Oncol Biol Phys 2008;72:575-581) Radhe Mohan pages 6-7 Full Text | Full-Text PDF (59 KB)
Scylla and Charybdis: Longer Beam-on Time or Lesser Conformality—the Dilemma of Tomotherapy C. Clifton Ling, Yves Archambault, Jiri Bocanek, C. Clifton Ling, Pengpeng Zhang, Thomas LoSasso, Grace Tang pages 8-9 Full Text | Full-Text PDF (60 KB)
Clinical Investigations
Prostate
Interval to Testosterone Recovery After Hormonal Therapy for Prostate Cancer and Risk of Death, 22 April 2009 Anthony V. D'Amico, Ming-Hui Chen, Andrew A. Renshaw, Marian Loffredo, Philip W. Kantoff pages 10-15 Abstract | Full Text | Full-Text PDF (216 KB)
Radiation Dose Predicts for Biochemical Control in Intermediate-Risk Prostate Cancer Patients Treated With Low-Dose-Rate Brachytherapy, 16 March 2009 Alice Y. Ho, Ryan J. Burri, Jamie A. Cesaretti, Nelson N. Stone, Richard G. Stock pages 16-22 Abstract | Full Text | Full-Text PDF (320 KB)
Genitourinary Toxicity After High-Dose-Rate (HDR) Brachytherapy Combined With Hypofractionated External Beam Radiotherapy for Localized Prostate Cancer: An Analysis to Determine the Correlation Between Dose–Volume Histogram Parameters in HDR Brachytherapy and Severity of Toxicity, 24 February 2009 Hiromichi Ishiyama, Masashi Kitano, Takefumi Satoh, Shouko Kotani, Mineko Uemae, Kazumasa Matsumoto, Hiroshi Okusa, Ken-ichi Tabata, Shiro Baba, Kazushige Hayakawa pages 23-28 Abstract | Full Text | Full-Text PDF (217 KB)
Dose–Volume Relationships for Acute Bowel Toxicity in Patients Treated With Pelvic Nodal Irradiation for Prostate Cancer, 20 May 2009 Claudio Fiorino, Filippo Alongi, Lucia Perna, Sara Broggi, Giovanni Mauro Cattaneo, Cesare Cozzarini, Nadia Di Muzio, Ferruccio Fazio, Riccardo Calandrino pages 29-35 Abstract | Full Text | Full-Text PDF (324 KB)
Maximum vs. Mono Androgen Blockade and the Risk of Recurrence in Men With Localized Prostate Cancer Undergoing Brachytherapy, 23 February 2009 Ronald C. Chen, Natalia Sadetsky, Ming-Hui Chen, Peter R. Carroll, Anthony V. D'Amico pages 36-39 Abstract | Full Text | Full-Text PDF (119 KB)
Dosimetric Changes Resulting From Patient Rotational Setup Errors in Proton Therapy Prostate Plans, 05 December 2008 Samir V. Sejpal, Richard A. Amos, Jaques B. Bluett, Lawrence B. Levy, Rajat J. Kudchadker, Jennifer Johnson, Seungtaek Choi, Andrew K. Lee pages 40-48 Abstract | Full Text | Full-Text PDF (707 KB)
Potential for Higher Treatment Failure in Obese Patients: Correlation of Elevated Body Mass Index and Increased Daily Prostate Deviations From the Radiation Beam Isocenters in an Analysis of 1,465 Computed Tomographic Images, 11 December 2008 James R. Wong, Zhanrong Gao, Scott Merrick, Paula Wilson, Minoru Uematsu, Kevin Woo, Chee-Wai Cheng pages 49-55 Abstract | Full Text | Full-Text PDF (467 KB)
Cervix
Dose–Volume Histogram Parameters and Local Tumor Control in Magnetic Resonance Image–Guided Cervical Cancer Brachytherapy, 16 March 2009 Johannes C.A. Dimopoulos, Stefan Lang, Christian Kirisits, Elena F. Fidarova, Daniel Berger, Petra Georg, Wolfgang Dörr, Richard Pötter pages 56-63 Abstract | Full Text | Full-Text PDF (228 KB)
Conformal Brachytherapy Planning for Cervical Cancer Using Transabdominal Ultrasound, 27 February 2009 Sylvia Van Dyk, Kailash Narayan, Richard Fisher, David Bernshaw pages 64-70 Abstract | Full Text | Full-Text PDF (220 KB)
Adrenal Gland
Stereotactic Body Radiotherapy for Treatment of Adrenal Metastases, 27 February 2009 Sheema Chawla, Yuhchyau Chen, Alan W. Katz, Ann G. Muhs, Abraham Philip, Paul Okunieff, Michael T. Milano pages 71-75 Abstract | Full Text | Full-Text PDF (146 KB)
Breast
Breast-Conserving Treatment in the Elderly: Long-Term Results of Adjuvant Hypofractionated and Normofractionated Radiotherapy, 27 January 2009 Youlia M. Kirova, Francois Campana, Alexia Savignoni, Fatima Laki, Marius Muresan, Remi Dendale, Marc A. Bollet, Remy J. Salmon, Alain Fourquet, Institut Curie Breast Cancer Study Group pages 76-81 Abstract | Full Text | Full-Text PDF (185 KB)
Does Three-Dimensional External Beam Partial Breast Irradiation Spare Lung Tissue Compared With Standard Whole Breast Irradiation?, 23 February 2009 Anudh K. Jain, Laura A. Vallow, Ashley A. Gale, Steven J. Buskirk pages 82-88 Abstract | Full Text | Full-Text PDF (310 KB)
Change in Seroma Volume During Whole-Breast Radiation Therapy, 13 April 2009 Rajiv Sharma, Marnee Spierer, Subhakar Mutyala, Nitika Thawani, Hillel W. Cohen, Linda Hong, Madhur K. Garg, Shalom Kalnicki pages 89-93 Abstract | Full Text | Full-Text PDF (1248 KB)
Individual Positioning: A Comparative Study of Adjuvant Breast Radiotherapy in the Prone Versus Supine Position, 23 March 2009 Zoltán Varga, Katalin Hideghéty, Tamás Mező, Alíz Nikolényi, László Thurzó, Zsuzsanna Kahán pages 94-100 Abstract | Full Text | Full-Text PDF (186 KB)
Head and Neck
Prospective Trial Incorporating Pre-/Mid-Treatment [18F]-Misonidazole Positron Emission Tomography for Head-and-Neck Cancer Patients Undergoing Concurrent Chemoradiotherapy, 09 February 2009 Nancy Lee, Sadek Nehmeh, Heiko Schöder, Matthew Fury, Kelvin Chan, C. Clifton Ling, John Humm pages 101-108 Abstract | Full Text | Full-Text PDF (901 KB)
Lung
Phase I Study of Oral S-1 Plus Cisplatin With Concurrent Radiotherapy for Locally Advanced Non–Small-Cell Lung Cancer, 16 October 2008 Kyoichi Kaira, Noriaki Sunaga, Noriko Yanagitani, Tadayoshi Kawata, Mitsuyoshi Utsugi, Kimihiro Shimizu, Takeshi Ebara, Hidemasa Kawamura, Tetsuo Nonaka, Hitoshi Ishikawa, Hideyuki Sakurai, Tatsuo Suga, Kenichiro Hara, Takeshi Hisada, Tamotsu Ishizuka, Takashi Nakano, Masatomo Mori pages 109-114 Abstract | Full Text | Full-Text PDF (112 KB)
Esophagus
Initial Stage Affects Survival Even After Complete Pathologic Remission is Achieved in Locally Advanced Esophageal Cancer: Analysis of 70 Patients With Pathologic Major Response After Preoperative Chemoradiotherapy, 02 March 2009 Min Kyoung Kim, Kyung-Ja Cho, Seung-Il Park, Yong Hee Kim, Jong Hoon Kim, Ho-Young Song, Ji Hoon Shin, Hwoon Yong Jung, Gin Hyug Lee, Kee Don Choi, Ho June Song, Jin-Sook Ryu, Sung-Bae Kim pages 115-121 Abstract | Full Text | Full-Text PDF (279 KB)
Late Toxicity After Definitive Concurrent Chemoradiotherapy for Thoracic Esophageal Carcinoma, 27 March 2009 Madoka Morota, Kotaro Gomi, Takuyo Kozuka, Keisho Chin, Masaaki Matsuura, Masahiko Oguchi, Hisao Ito, Takashi Yamashita pages 122-128 Abstract | Full Text | Full-Text PDF (268 KB)
Rectum
Neoadjuvant Treatment Does Not Influence Perioperative Outcome in Rectal Cancer Surgery, 23 March 2009 Alexis Ulrich, Jürgen Weitz, Matthias Slodczyk, Moritz Koch, Dirk Jaeger, Marc Münter, Markus W. Büchler pages 129-136 Abstract | Full Text | Full-Text PDF (121 KB)
Expression of FXYD-3 is an Independent Prognostic Factor in Rectal Cancer Patients With Preoperative Radiotherapy, 16 March 2009 Per Loftås, Sofia Önnesjö, Emma Widegren, Gunnar Adell, Hany Kayed, Jörg Kleeff, Hanswalter Zentgraf, Xiao-Feng Sun pages 137-142 Abstract | Full Text | Full-Text PDF (368 KB)
Anal Canal
Outcomes of Chemoradiotherapy With 5-Fluorouracil and Mitomycin C for Anal Cancer in Immunocompetent Versus Immunodeficient Patients, 09 February 2009 Yuji Seo, Michael T. Kinsella, Harry L. Reynolds, Gregory Chipman, Scot C. Remick, Timothy J. Kinsella pages 143-149 Abstract | Full Text | Full-Text PDF (225 KB)
Gallbladder
Adjuvant Therapy for Gallbladder Carcinoma: The Mayo Clinic Experience, 17 March 2009 Douglas G. Gold, Robert C. Miller, Michael G. Haddock, Leonard L. Gunderson, Fernando Quevedo, John H. Donohue, Sumita Bhatia, David M. Nagorney pages 150-155 Abstract | Full Text | Full-Text PDF (130 KB)
Brain
Safety and Efficacy of Bevacizumab With Hypofractionated Stereotactic Irradiation for Recurrent Malignant Gliomas, 23 January 2009 Philip H. Gutin, Fabio M. Iwamoto, Kathryn Beal, Nimish A. Mohile, Sasan Karimi, Bob L. Hou, Stella Lymberis, Yoshiya Yamada, Jenghwa Chang, Lauren E. Abrey pages 156-163 Abstract | Full Text | Full-Text PDF (854 KB)
Effects of Concurrent Topotecan and Radiation on 6-Month Progression-Free Survival in the Primary Treatment of Glioblastoma Multiforme Gerhard G. Grabenbauer, Klaus-Dieter Gerber, Oliver Ganslandt, Andrea Richter, Gunther Klautke, Josef Birkmann, Martin Meyer pages 164-169 Abstract | Full Text | Full-Text PDF (202 KB)
Eye
Dose De-Escalation With Gamma Knife Radiosurgery in the Treatment of Choroidal Melanoma, 16 March 2009 Clemens M. Schirmer, Michael Chan, John Mignano, Jay Duker, Christopher S. Melhus, Lloyd B. Williams, Julian K. Wu, Kevin C. Yao pages 170-176 Abstract | Full Text | Full-Text PDF (790 KB)
Sarcoma
Successful Treatment of High Risk and Recurrent Pediatric Desmoids Using Radiation as a Component of Multimodality Therapy, 01 May 2009 Siavash Jabbari, David Andolino, Vivian Weinberg, Brian T. Missett, Jason Law, William M. Wara, Richard J. O'Donnell, Katherine K. Matthay, Steven G. DuBois, Robert Goldsby, Daphne A. Haas-Kogan pages 177-182 Abstract | Full Text | Full-Text PDF (144 KB) | Add-Ons
External Beam Radiation Therapy Enhances Local Control in Pigmented Villonodular Synovitis, 11 February 2009 Melissa Horoschak, Phuoc T. Tran, Pavan Bachireddy, Robert B. West, David Mohler, Christopher F. Beaulieu, Daniel S. Kapp, Sarah S. Donaldson pages 183-187 Abstract | Full Text | Full-Text PDF (125 KB)
Lymphoma
Patterns and Timing of Initial Relapse in Patients Subsequently Undergoing Transplantation for Hodgkin's Lymphoma, 27 February 2009 Sughosh Dhakal, Tithi Biswas, Jane L. Liesveld, Jonathan W. Friedberg, Gordon L. Phillips, Louis S. Constine pages 188-192 Abstract | Full Text | Full-Text PDF (110 KB)
Palliation
Determining the Incidence of Pain Flare Following Palliative Radiotherapy for Symptomatic Bone Metastases: Results From Three Canadian Cancer Centers, 23 January 2009 Amanda Hird, Edward Chow, Liying Zhang, Rebecca Wong, Jackson Wu, Emily Sinclair, Cyril Danjoux, May Tsao, Elizabeth Barnes, Andrew Loblaw pages 193-197 Abstract | Full Text | Full-Text PDF (138 KB)
Biology Contributions
Combination of the Pro-Apoptotic TRAIL-Receptor Antibody Mapatumumab With Ionizing Radiation Strongly Increases Long-Term Tumor Control Under Ambient and Hypoxic Conditions Patrizia Marini, Wilfried Budach, Maximilian Niyazi, Dorothea Junginger, Stefan Stickl, Verena Jendrossek, Claus Belka pages 198-202 Abstract | Full Text | Full-Text PDF (179 KB)
The Prognostic Value of TRAIL and its Death Receptors in Cervical Cancer John H. Maduro, Maartje G. Noordhuis, Klaske A. ten Hoor, Elisabeth Pras, Henriette J.G. Arts, Jasper J.H. Eijsink, Harry Hollema, Constantijne H. Mom, Steven de Jong, Elisabeth G.E. de Vries, Geertruida H. de Bock, Ate G.J. van der Zee pages 203-211 Abstract | Full Text | Full-Text PDF (4800 KB)
Radiosensitizing Effects of Temozolomide Observed in vivo only in a Subset of O6-Methylguanine-DNA Methyltransferase Methylated Glioblastoma Multiforme Xenografts Brett L. Carlson, Patrick T. Grogan, Ann C. Mladek, Mark A. Schroeder, Gaspar J. Kitange, Paul A. Decker, Caterina Giannini, Wenting Wu, Karla A. Ballman, C. David James, Jann N. Sarkaria pages 212-219 Abstract | Full Text | Full-Text PDF (216 KB) | Add-Ons
Mobilization of Circulating Vascular Progenitors in Cancer Patients Receiving External Beam Radiation in Response to Tissue Injury David S. Allan, Scott C. Morgan, Paul E. Birch, Lin Yang, Michael J. Halpenny, Angelo Gunanayagam, Yuhua Li, Libni Eapen pages 220-224 Abstract | Full Text | Full-Text PDF (339 KB)
Modulation of Ionizing Radiation-Induced G2 Arrest by Cyclooxygenase-2 and its Inhibitor Celecoxib Hyun Jung Jun, Young Mee Kim, Soo Yeon Park, Ji Sun Park, Eun Jung Lee, Shin Ae Choi, Hongryull Pyo pages 225-234 Abstract | Full Text | Full-Text PDF (958 KB) | Add-Ons
ATM-Dependent Hyper-Radiosensitivity in Mammalian Cells Irradiated by Heavy Ions Lian Xue, Dong Yu, Yoshiya Furusawa, Jianping Cao, Ryuichi Okayasu, Saijun Fan pages 235-243 Abstract | Full Text | Full-Text PDF (782 KB)
Response Surface Methodology: An Extensive Potential to Optimize in vivo Photodynamic Therapy Conditions, 14 July 2009 Loraine Tirand, Thierry Bastogne, Denise Bechet, Michel Linder, Noémie Thomas, Céline Frochot, François Guillemin, Muriel Barberi-Heyob pages 244-252 Abstract | Full Text | Full-Text PDF (593 KB)
Physics Contributions
Whole-Brain Radiotherapy With Simultaneous Integrated Boost to Multiple Brain Metastases Using Volumetric Modulated Arc Therapy, 06 July 2009 Frank J. Lagerwaard, Elles A.P. van der Hoorn, Wilko F.A.R. Verbakel, Cornelis J.A. Haasbeek, Ben J. Slotman, Suresh Senan pages 253-259 Abstract | Full Text | Full-Text PDF (660 KB)
Inferences About Prostate Intrafraction Motion From Pre- and Posttreatment Volumetric Imaging, 09 June 2009 Justus Adamson, Qiuwen Wu pages 260-267 Abstract | Full Text | Full-Text PDF (1020 KB)
Do Tumors in the Lung Deform During Normal Respiration? An Image Registration Investigation, 09 June 2009 Jianzhou Wu, Peng Lei, Raj Shekhar, Huiling Li, Mohan Suntharalingam, Warren D. D'Souza pages 268-275 Abstract | Full Text | Full-Text PDF (316 KB)
Dynamic MRI of Grid-Tagged Hyperpolarized Helium-3 for the Assessment of Lung Motion During Breathing, 19 June 2009 Jing Cai, Ke Sheng, Stanley H. Benedict, Paul W. Read, James M. Larner, John P. Mugler, Eduard E. de Lange, Gordon D. Cates, G. Wilson Miller pages 276-284 Abstract | Full Text | Full-Text PDF (1898 KB)
MRI Guidance for Accelerated Partial Breast Irradiation in Prone Position: Imaging Protocol Design and Evaluation, 24 July 2009 Kang-Hyun Ahn, Brian A. Hargreaves, Marcus T. Alley, Kathleen C. Horst, Gary Luxton, Bruce L. Daniel, Dimitre Hristov pages 285-293 Abstract | Full Text | Full-Text PDF (776 KB)
Accelerated Partial Breast Irradiation: What is Dosimetric Effect of Advanced Technology Approaches?, 19 June 2009 Jean M. Moran, Merav A. Ben-David, Robin B. Marsh, James M. Balter, Kent A. Griffith, James A. Hayman, Lori J. Pierce pages 294-301 Abstract | Full Text | Full-Text PDF (1241 KB)
Inter- and Intrafraction Variability in Liver Position in Non–Breath-Hold Stereotactic Body Radiotherapy, 22 July 2009 Robert B. Case, Jan-Jakob Sonke, Douglas J. Moseley, John Kim, Kristy K. Brock, Laura A. Dawson pages 302-308 Abstract | Full Text | Full-Text PDF (431 KB)
Single Versus Customized Treatment Planning for Image-guided High-Dose-Rate Brachytherapy for Cervical Cancer: Dosimetric Comparison and Predicting Factor for Organs at Risk Overdose With Single Plan Approach, 19 June 2009 Alexander Chi, Mingcheng Gao, James Sinacore, Nam P. Nguyen, Faisal Vali, Kevin Albuquerque pages 309-314 Abstract | Full Text | Full-Text PDF (251 KB)
Letters to the Editor
Modeling the Contribution of Synchronous Chemotherapy to the Rate of Grade 3 and 4 Mucositis in Locally Advanced Squamous Cell Carcinoma of the Head and Neck Andrew Hartley, Paul Sanghera, John Glaholm, Jack F. Fowler page 315 Full Text | Full-Text PDF (65 KB)
In Reply to Dr. Hartley Irwin H. Lee, Avraham Eisbruch page 315 Full Text | Full-Text PDF (62 KB)
Predicting the Risk of Pelvic Node Involvement Among Men With Prostate Cancer in the Contemporary Era: Change you can Believe in, or Back to the Future? (In Regard to Nguyen PL, et al. (Int J Radiat Oncol Biol Phys 2009) Mack Roach page 316 Full Text | Full-Text PDF (61 KB)
In Reply to Dr. Roach et al. Paul L. Nguyen, Anthony V. D'Amico page 316 Full Text | Full-Text PDF (56 KB)
In Reply to Drs. Larson and Sahgal Paul D. Brown, Andrew Y. Kee, Jeffrey S. Eshleman, John B. Fiveash pages 316-317 Full Text | Full-Text PDF (71 KB)
Tomotherapy Versus Conventional Planning for Left-Sided Breast Cancer With Lymph Nodes—Dosimetric Comparison: In Regard to Goddu et al. (Int J Radiat Oncol Biol Phys 2009;73:1243–1251) Dimitris N. Mihailidis, Michael Harmon page 317 Full Text | Full-Text PDF (53 KB)
In Reply to Drs. Mihailidis and Harmon S. Murty Goddu, Olga L. Pechenaya, Daniel A. Low pages 317-318 Full Text | Full-Text PDF (67 KB)
In Reply to Dr. Xiao et al. Cohen W. Hurkmans, Johan P. Cuijpers, Frank J. Lagerwaard, Joachim Widder, Uulke A. van der Heide, Danny Schuring, Suresh Senan page 318 Full Text | Full-Text PDF (48 KB)
In Reply to Dr. Hurkmans et al. Ying Xiao, Lech S. Papiez, James M. Galvin page 318 Full Text | Full-Text PDF (48 KB)
Elective Nodal Irradiation Gilbert A. Lawrence, Clark M. Brown pages 318-319 Full Text | Full-Text PDF (55 KB)
Meetings page 320 Full Text | Full-Text PDF (54 KB)
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